ICD-10-CM (2010)/CHAPTER 2

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Neoplasms (C00-D48)[edit]

This chapter contains the following broad groups of neoplasms:
C00-C75 Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
C15-C26 Malignant neoplasms of digestive organs
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
C40-C41 Malignant neoplasms of bone and articular cartilage

C43-C44 Malignant neoplasms of skin
C45-C49 Malignant neoplasms of mesothelial and soft tissue
C50 Malignant neoplasms of breast
C51-C58 Malignant neoplasms of female genital organs
C60-C63 Malignant neoplasms of male genital organs
C64-C68 Malignant neoplasms of urinary tract
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
C7a Malignant neuroendocrine tumors
C7b Secondary neuroendocrine tumors
C76-C80 Malignant neoplasms of ill-defined, other secondary and unspecified sites
C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue
D00-D09 In situ neoplasms
D10-D36 Benign neoplasms, except benign neuroendocrine tumors
D3a Benign neuroendocrine tumors
D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
D49 Neoplasms of unspecified behavior


Notes: Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.


Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes. To identify the morphology for the majority of Chapter 2 codes that do not include the histologic type, comprehensive separate morphology codes are provided. These morphology codes are derived from the International Classification of Diseases for Oncology (ICD-O).


Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ("overlapping lesion"), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.


Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Malignant neoplasms (C00-C96)

Use additional morphology codes with behavior code /3
Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue (C00-C75)

Malignant neoplasm of lip, oral cavity and pharynx (C00-C14)[edit]

C00 Malignant neoplasm of lip[edit]

Excludes1: malignant neoplasm of skin of lip (C43.0, C44.0)
Merkel cell carcinoma of lip (C4a.0)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C00.0 Malignant neoplasm of external upper lip
Malignant neoplasm of lipstick area of upper lip
Malignant neoplasm of upper lip NOS
Malignant neoplasm of vermilion border of upper lip
C00.1 Malignant neoplasm of external lower lip
Malignant neoplasm of lower lip NOS
Malignant neoplasm of lipstick area of lower lip
Malignant neoplasm of vermilion border of lower lip
C00.2 Malignant neoplasm of external lip, unspecified
Malignant neoplasm of vermilion border of lip NOS
C00.3 Malignant neoplasm of upper lip, inner aspect
Malignant neoplasm of buccal aspect of upper lip
Malignant neoplasm of frenulum of upper lip
Malignant neoplasm of mucosa of upper lip
Malignant neoplasm of oral aspect of upper lip
C00.4 Malignant neoplasm of lower lip, inner aspect
Malignant neoplasm of buccal aspect of lower lip
Malignant neoplasm of frenulum of lower lip
Malignant neoplasm of mucosa of lower lip
Malignant neoplasm of oral aspect of lower lip
C00.5 Malignant neoplasm of lip, unspecified, inner aspect
Malignant neoplasm of buccal aspect of lip, unspecified
Malignant neoplasm of frenulum of lip, unspecified
Malignant neoplasm of mucosa of lip, unspecified
Malignant neoplasm of oral aspect of lip, unspecified
C00.6 Malignant neoplasm of commissure of lip, unspecified
C00.8 Malignant neoplasm of overlapping sites of lip
C00.9 Malignant neoplasm of lip, unspecified

C01 Malignant neoplasm of base of tongue[edit]

Includes: malignant neoplasm of dorsal surface of base of tongue
malignant neoplasm of fixed part of tongue NOS
malignant neoplasm of posterior third of tongue
Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)

C02 Malignant neoplasm of other and unspecified parts of tongue[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C02.0 Malignant neoplasm of dorsal surface of tongue
Malignant neoplasm of anterior two-thirds of tongue, dorsal surface
Excludes2: malignant neoplasm of dorsal surface of base of tongue (C01)
C02.1 Malignant neoplasm of border of tongue
Malignant neoplasm of tip of tongue
C02.2 Malignant neoplasm of ventral surface of tongue
Malignant neoplasm of anterior two-thirds of tongue, ventral surface
Malignant neoplasm of frenulum linguae
C02.3 Malignant neoplasm of anterior two-thirds of tongue, part unspecified
Malignant neoplasm of middle third of tongue NOS
Malignant neoplasm of mobile part of tongue NOS
C02.4 Malignant neoplasm of lingual tonsil
Excludes2: malignant neoplasm of tonsil NOS (C09.9)
C02.8 Malignant neoplasm of overlapping sites of tongue
Malignant neoplasm of two or more contiguous sites of tongue
C02.9 Malignant neoplasm of tongue, unspecified

C03 Malignant neoplasm of gum[edit]

Includes: malignant neoplasm of alveolar (ridge) mucosa
malignant neoplasm of gingiva
Excludes2: malignant odontogenic neoplasms (C41.0-C41.1)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C03.0 Malignant neoplasm of upper gum
C03.1 Malignant neoplasm of lower gum
C03.9 Malignant neoplasm of gum, unspecified

C04 Malignant neoplasm of floor of mouth[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C04.0 Malignant neoplasm of anterior floor of mouth
Malignant neoplasm of anterior to the premolar-canine junction
C04.1 Malignant neoplasm of lateral floor of mouth
C04.8 Malignant neoplasm of overlapping sites of floor of mouth
C04.9 Malignant neoplasm of floor of mouth, unspecified

C05 Malignant neoplasm of palate[edit]

Excludes1: Kaposi's sarcoma of palate (C46.2)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C05.0 Malignant neoplasm of hard palate
C05.1 Malignant neoplasm of soft palate
Excludes2: malignant neoplasm of nasopharyngeal surface of soft palate (C11.3)
C05.2 Malignant neoplasm of uvula
C05.8 Malignant neoplasm of overlapping sites of palate
C05.9 Malignant neoplasm of palate, unspecified
Malignant neoplasm of roof of mouth

C06 Malignant neoplasm of other and unspecified parts of mouth[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C06.0 Malignant neoplasm of cheek mucosa
Malignant neoplasm of buccal mucosa NOS
Malignant neoplasm of internal cheek
C06.1 Malignant neoplasm of vestibule of mouth
Malignant neoplasm of buccal sulcus (upper) (lower)
Malignant neoplasm of labial sulcus (upper) (lower)
C06.2 Malignant neoplasm of retromolar area
C06.8 Malignant neoplasm of overlapping sites of other and unspecified parts of mouth
C06.80 Malignant neoplasm of overlapping sites of unspecified parts of mouth
C06.89 Malignant neoplasm of overlapping sites of other parts of mouth
"book leaf" neoplasm [ventral surface of tongue and floor of mouth]
C06.9 Malignant neoplasm of mouth, unspecified
Malignant neoplasm of minor salivary gland, unspecified side
Malignant neoplasm of oral cavity NOS

C07 Malignant neoplasm of parotid gland[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)

C08 Malignant neoplasm of other and unspecified major salivary glands[edit]

Includes: malignant neoplasm of salivary ducts
Excludes1: malignant neoplasms of specified minor salivary glands which are classified according to their anatomical location
Excludes2: malignant neoplasms of minor salivary glands NOS (C06.9)
malignant neoplasm of parotid gland (C07)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C08.0 Malignant neoplasm of submandibular gland
Malignant neoplasm of submaxillary gland
C08.1 Malignant neoplasm of sublingual gland
C08.9 Malignant neoplasm of major salivary gland, unspecified
Malignant neoplasm of salivary gland (major) NOS

C09 Malignant neoplasm of tonsil[edit]

Excludes2: malignant neoplasm of lingual tonsil (C02.4)
malignant neoplasm of pharyngeal tonsil (C11.1)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C09.0 Malignant neoplasm of tonsillar fossa
C09.1 Malignant neoplasm of tonsillar pillar (anterior) (posterior)
C09.8 Malignant neoplasm of overlapping sites of tonsil
C09.9 Malignant neoplasm of tonsil, unspecified
Malignant neoplasm of tonsil NOS
Malignant neoplasm of faucial tonsils
Malignant neoplasm of palatine tonsils

C10 Malignant neoplasm of oropharynx[edit]

Excludes2: malignant neoplasm of tonsil (C09.-)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C10.0 Malignant neoplasm of vallecula
C10.1 Malignant neoplasm of anterior surface of epiglottis
Malignant neoplasm of epiglottis, free border [margin]
Malignant neoplasm of glossoepiglottic fold(s)
Excludes2: malignant neoplasm of epiglottis (suprahyoid portion) NOS (C32.1)
C10.2 Malignant neoplasm of lateral wall of oropharynx
C10.3 Malignant neoplasm of posterior wall of oropharynx
C10.4 Malignant neoplasm of branchial cleft
Malignant neoplasm of branchial cyst [site of neoplasm]
C10.8 Malignant neoplasm of overlapping sites of oropharynx
Malignant neoplasm of junctional region of oropharynx
C10.9 Malignant neoplasm of oropharynx, unspecified

C11 Malignant neoplasm of nasopharynx[edit]

Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C11.0 Malignant neoplasm of superior wall of nasopharynx
Malignant neoplasm of roof of nasopharynx
C11.1 Malignant neoplasm of posterior wall of nasopharynx
Malignant neoplasm of adenoid
Malignant neoplasm of pharyngeal tonsil
C11.2 Malignant neoplasm of lateral wall of nasopharynx
Malignant neoplasm of fossa of Rosenm?ller
Malignant neoplasm of opening of auditory tube
Malignant neoplasm of pharyngeal recess
C11.3 Malignant neoplasm of anterior wall of nasopharynx
Malignant neoplasm of floor of nasopharynx
Malignant neoplasm of nasopharyngeal (anterior) (posterior) surface of soft palate
Malignant neoplasm of posterior margin of nasal choana
Malignant neoplasm of posterior margin of nasal septum
C11.8 Malignant neoplasm of overlapping sites of nasopharynx
C11.9 Malignant neoplasm of nasopharynx, unspecified
Malignant neoplasm of nasopharyngeal wall NOS

C12 Malignant neoplasm of pyriform sinus[edit]

Includes: malignant neoplasm of pyriform fossa
Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)

C13 Malignant neoplasm of hypopharynx[edit]

Excludes2: malignant neoplasm of pyriform sinus (C12)
Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C13.0 Malignant neoplasm of postcricoid region
C13.1 Malignant neoplasm of aryepiglottic fold, hypopharyngeal aspect
Malignant neoplasm of aryepiglottic fold NOS
Malignant neoplasm of interarytenoid fold NOS
Malignant neoplasm of aryepiglottic fold marginal zone
Malignant neoplasm of interarytenoid fold marginal zone
Excludes2: malignant neoplasm of aryepiglottic fold or interarytenoid fold, laryngeal aspect (C32.1)
C13.2 Malignant neoplasm of posterior wall of hypopharynx
C13.8 Malignant neoplasm of overlapping sites of hypopharynx
C13.9 Malignant neoplasm of hypopharynx, unspecified
Malignant neoplasm of hypopharyngeal wall NOS

C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx[edit]

Excludes1: malignant neoplasm of oral cavity NOS (C06.9)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C14.0 Malignant neoplasm of pharynx, unspecified
C14.2 Malignant neoplasm of Waldeyer's ring
C14.8 Malignant neoplasm of overlapping sites of lip, oral cavity and pharynx
Primary malignant neoplasm of two or more contiguous sites of lip, oral cavity and pharynx
Excludes1: "book leaf" neoplasm [ventral surface of tongue and floor of mouth] (C06.89)

Malignant neoplasm of digestive organs (C15-C26)[edit]

Excludes1: Kaposi's sarcoma of gastrointestinal sites (C46.4)

C15 Malignant neoplasm of esophagus[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
C15.3 Malignant neoplasm of upper third of esophagus
C15.4 Malignant neoplasm of middle third of esophagus
C15.5 Malignant neoplasm of lower third of esophagus
Excludes1: malignant neoplasm of cardio-esophageal junction (C16.0)
C15.8 Malignant neoplasm of overlapping sites of esophagus
C15.9 Malignant neoplasm of esophagus, unspecified

C16 Malignant neoplasm of stomach[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
Excludes2: malignant carcinoid tumor of the stomach (C7a.092)
C16.0 Malignant neoplasm of cardia
Malignant neoplasm of cardiac orifice
Malignant neoplasm of cardio-esophageal junction
Malignant neoplasm of esophagus and stomach
Malignant neoplasm of gastro-esophageal junction
C16.1 Malignant neoplasm of fundus of stomach
C16.2 Malignant neoplasm of body of stomach
C16.3 Malignant neoplasm of pyloric antrum
Malignant neoplasm of gastric antrum
C16.4 Malignant neoplasm of pylorus
Malignant neoplasm of prepylorus
Malignant neoplasm of pyloric canal
C16.5 Malignant neoplasm of lesser curvature of stomach, unspecified
Malignant neoplasm of lesser curvature of stomach, not classifiable to C16.1-C16.4
C16.6 Malignant neoplasm of greater curvature of stomach, unspecified
Malignant neoplasm of greater curvature of stomach, not classifiable to C16.0-C16.4
C16.8 Malignant neoplasm of overlapping sites of stomach
C16.9 Malignant neoplasm of stomach, unspecified
Gastric cancer NOS

C17 Malignant neoplasm of small intestine[edit]

Excludes1: malignant carcinoid tumors of the small intestine (C7a.01)
C17.0 Malignant neoplasm of duodenum
C17.1 Malignant neoplasm of jejunum
C17.2 Malignant neoplasm of ileum
Excludes1: malignant neoplasm of ileocecal valve (C18.0)
C17.3 Meckel's diverticulum
C17.8 Malignant neoplasm of overlapping sites of small intestine
C17.9 Malignant neoplasm of small intestine, unspecified

C18 Malignant neoplasm of colon[edit]

Excludes1: malignant carcinoid tumors of the colon (C7a.02-)
C18.0 Malignant neoplasm of cecum
Malignant neoplasm of ileocecal valve
C18.1 Malignant neoplasm of appendix
C18.2 Malignant neoplasm of ascending colon
C18.3 Malignant neoplasm of hepatic flexure
C18.4 Malignant neoplasm of transverse colon
C18.5 Malignant neoplasm of splenic flexure
C18.6 Malignant neoplasm of descending colon
C18.7 Malignant neoplasm of sigmoid colon
Malignant neoplasm of sigmoid (flexure)
Excludes1: malignant neoplasm of rectosigmoid junction (C19)
C18.8 Malignant neoplasm of overlapping sites of colon
C18. 9 Malignant neoplasm of colon, unspecified
Malignant neoplasm of large intestine NOS

C19 Malignant neoplasm of rectosigmoid junction[edit]

Includes: malignant neoplasm of colon with rectum
malignant neoplasm of rectosigmoid (colon)
Excludes1: malignant carcinoid tumors of the colon (C7a.02-)

C20 Malignant neoplasm of rectum[edit]

Includes: malignant neoplasm of rectal ampulla
Excludes1: malignant carcinoid tumor of the rectum (C7a.026)

C21 Malignant neoplasm of anus and anal canal[edit]

Excludes2: malignant carcinoid tumors of the colon (C7a.02-)
malignant melanoma of anal margin (C43.51)
malignant melanoma of anal skin (C43.51)
malignant melanoma of perianal skin (C43.51)
malignant neoplasm of anal margin (C44.51)
malignant neoplasm of anal skin (C44.51)
malignant neoplasm of perianal skin (C44.51)
C21.0 Malignant neoplasm of anus, unspecified
C21.1 Malignant neoplasm of anal canal
Malignant neoplasm of anal sphincter
C21.2 Malignant neoplasm of cloacogenic zone
C21.8 Malignant neoplasm of overlapping sites of rectum, anus and anal canal
Malignant neoplasm of anorectal junction
Malignant neoplasm of anorectum
Primary malignant neoplasm of two or more contiguous sites of rectum, anus and anal canal

C22 Malignant neoplasm of liver and intrahepatic bile ducts[edit]

Excludes1: malignant neoplasm of biliary tract NOS (C24.9)
secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
Use additional code to identify:
alcohol abuse and dependence (F10.-)
hepatitis B (B16.-, B18.0-B18.1)
hepatitis C (B17.1-, B18.2)
C22.0 Liver cell carcinoma
Hepatocellular carcinoma
Hepatoma
C22.1 Intrahepatic bile duct carcinoma
Cholangiocarcinoma
Excludes1: malignant neoplasm of hepatic duct (C24.0)
C22.2 Hepatoblastoma
C22.3 Angiosarcoma of liver
Kupffer cell sarcoma
C22.4 Other sarcomas of liver
C22.7 Other specified carcinomas of liver
C22.8 Malignant neoplasm of liver, primary, unspecified as to type
C22.9 Malignant neoplasm of liver, not specified as primary or secondary

C23 Malignant neoplasm of gallbladder[edit]

C24 Malignant neoplasm of other and unspecified parts of biliary tract[edit]

Excludes1: malignant neoplasm of intrahepatic bile duct (C22.1)
C24.0 Malignant neoplasm of extrahepatic bile duct
Malignant neoplasm of biliary duct or passage NOS
Malignant neoplasm of common bile duct
Malignant neoplasm of cystic duct
Malignant neoplasm of hepatic duct
C24.1 Malignant neoplasm of ampulla of Vater
C24.8 Malignant neoplasm of overlapping sites of biliary tract
Malignant neoplasm involving both intrahepatic and extrahepatic bile ducts
Primary malignant neoplasm of two or more contiguous sites of biliary tract
C24.9 Malignant neoplasm of biliary tract, unspecified

C25 Malignant neoplasm of pancreas[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
C25.0 Malignant neoplasm of head of pancreas
C25.1 Malignant neoplasm of body of pancreas
C25.2 Malignant neoplasm of tail of pancreas
C25.3 Malignant neoplasm of pancreatic duct
C25.4 Malignant neoplasm of endocrine pancreas
Malignant neoplasm of islets of Langerhans
Use additional code to identify any functional activity.
C25.7 Malignant neoplasm of other parts of pancreas
Malignant neoplasm of neck of pancreas
C25.8 Malignant neoplasm of overlapping sites of pancreas
C25.9 Malignant neoplasm of pancreas, unspecified

C26 Malignant neoplasm of other and ill-defined digestive organs[edit]

Excludes1: malignant neoplasm of peritoneum and retroperitoneum (C48.-)
C26.0 Malignant neoplasm of intestinal tract, part unspecified
Malignant neoplasm of intestine NOS
C26.1 Malignant neoplasm of spleen
Excludes1: Hodgkin lymphoma (C81.-)
nonHodgkin lymphoma (C82-C85)
C26.9 Malignant neoplasm of ill-defined sites within the digestive system
Malignant neoplasm of alimentary canal or tract NOS
Malignant neoplasm of gastrointestinal tract NOS
Excludes1: malignant neoplasm of abdominal NOS (C76.2)
malignant neoplasm of intra-abdominal NOS (C76.2)

Malignant neoplasm of respiratory and intrathoracic organs (C30-C39)[edit]

Includes: malignant neoplasm of middle ear
Excludes1: mesothelioma (C45.-)

C30 Malignant neoplasm of nasal cavity and middle ear[edit]

C30.0 Malignant neoplasm of nasal cavity
Malignant neoplasm of cartilage of nose
Malignant neoplasm of nasal concha
Malignant neoplasm of internal nose
Malignant neoplasm of septum of nose
Malignant neoplasm of vestibule of nose
Excludes1: malignant neoplasm of nasal bone (C41.0)
malignant neoplasm of nose NOS (C76.0)
malignant neoplasm of olfactory bulb (C72.2-)
malignant neoplasm of posterior margin of nasal septum and choana (C11.3)
malignant neoplasm of skin of nose (C43.31, C44.31)
malignant neoplasm of turbinates (C41.0)
C30.1 Malignant neoplasm of middle ear
Malignant neoplasm of antrum tympanicum
Malignant neoplasm of auditory tube
Malignant neoplasm of eustachian tube
Malignant neoplasm of inner ear
Malignant neoplasm of mastoid air cells
Malignant neoplasm of tympanic cavity
Excludes1: malignant neoplasm of auricular canal (external) (C43.2-,C44.2-)
malignant neoplasm of bone of ear (meatus) (C41.0)
malignant neoplasm of cartilage of ear (C49.0)
malignant neoplasm of skin of (external) ear (C43.2-, C44.2-)

C31 Malignant neoplasm of accessory sinuses[edit]

C31.0 Malignant neoplasm of maxillary sinus
Malignant neoplasm of antrum (Highmore) (maxillary)
C31.1 Malignant neoplasm of ethmoidal sinus
C31.2 Malignant neoplasm of frontal sinus
C31. 3 Malignant neoplasm of sphenoid sinus
C31.8 Malignant neoplasm of overlapping sites of accessory sinuses
C31.9 Malignant neoplasm of accessory sinus, unspecified

C32 Malignant neoplasm of larynx[edit]

Use additional code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C32.0 Malignant neoplasm of glottis
Malignant neoplasm of intrinsic larynx
Malignant neoplasm of laryngeal commissure (anterior)(posterior)
Malignant neoplasm of vocal cord (true) NOS
C32.1 Malignant neoplasm of supraglottis
Malignant neoplasm of aryepiglottic fold or interarytenoid fold, laryngeal aspect
Malignant neoplasm of epiglottis (suprahyoid portion) NOS
Malignant neoplasm of extrinsic larynx
Malignant neoplasm of false vocal cord
Malignant neoplasm of posterior (laryngeal) surface of epiglottis
Malignant neoplasm of ventricular bands
Excludes2: malignant neoplasm of anterior surface of epiglottis (C10.1)
malignant neoplasm of aryepiglottic fold or interarytenoid fold:
NOS (C13.1)
hypopharyngeal aspect (C13.1)
marginal zone (C13.1)
C32.2 Malignant neoplasm of subglottis
C32.3 Malignant neoplasm of laryngeal cartilage
C32.8 Malignant neoplasm of overlapping sites of larynx
C32.9 Malignant neoplasm of larynx, unspecified

C33 Malignant neoplasm of trachea[edit]

Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)

C34 Malignant neoplasm of bronchus and lung[edit]

Excludes1: Kaposi's sarcoma of lung (C46.5-)
malignant carcinoid tumor of the bronchus and lung (C7a.090)
Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C34.0 Malignant neoplasm of main bronchus
Malignant neoplasm of carina
Malignant neoplasm of hilus (of lung)
C34.00 Malignant neoplasm of main bronchus, unspecified side
C34.01 Malignant neoplasm of right main bronchus
C34.02 Malignant neoplasm of left main bronchus
C34.1 Malignant neoplasm of upper lobe, bronchus or lung
C34.10 Malignant neoplasm of upper lobe, bronchus or lung, unspecified side
C34.11 Malignant neoplasm of upper lobe, right bronchus or lung
C34.12 Malignant neoplasm of upper lobe, left bronchus or lung
C34.2 Malignant neoplasm of middle lobe, right bronchus or lung
C34.3 Malignant neoplasm of lower lobe, bronchus or lung
C34.30 Malignant neoplasm of lower lobe, bronchus or lung, unspecified side
C34.31 Malignant neoplasm of lower lobe, right bronchus or lung
C34.32 Malignant neoplasm of lower lobe, left bronchus or lung
C34.8 Malignant neoplasm of overlapping sites of bronchus and lung
C34.80 Malignant neoplasm of overlapping sites of bronchus and lung, unspecified side
C34.81 Malignant neoplasm of overlapping sites of right bronchus and lung
C34.82 Malignant neoplasm of overlapping sites of left bronchus and lung
C34.9 Malignant neoplasm of bronchus or lung, unspecified
C34.90 Malignant neoplasm of bronchus or lung, unspecified, unspecified side
C34.91 Malignant neoplasm of right bronchus or lung, unspecified
C34.92 Malignant neoplasm of left bronchus or lung, unspecified

C37 Malignant neoplasm of thymus[edit]

Excludes1: malignant carcinoid tumor of the thymus (C7a.091)

C38 Malignant neoplasm of heart, mediastinum and pleura[edit]

Excludes1: mesothelioma (C45.-)
C38.0 Malignant neoplasm of heart
Malignant neoplasm of pericardium
Excludes1: malignant neoplasm of great vessels (C49.3)
C38.1 Malignant neoplasm of anterior mediastinum
C38.2 Malignant neoplasm of posterior mediastinum
C38.3 Malignant neoplasm of mediastinum, part unspecified
C38.4 Malignant neoplasm of pleura
C38.8 Malignant neoplasm of overlapping sites of heart, mediastinum and pleura

C39 Malignant neoplasm of other and ill-defined sites in the respiratory system[edit]

Excludes1: intrathoracic malignant neoplasm NOS (C76.1)
thoracic malignant neoplasm NOS (C76.1)
Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
C39.0 Malignant neoplasm of upper respiratory tract, part unspecified
C39.9 Malignant neoplasm of lower respiratory tract, part unspecified
Malignant neoplasm of respiratory tract NOS

Malignant neoplasm of bone and articular cartilage (C40-C41)[edit]

Includes: malignant neoplasm of cartilage (articular) (joint)
malignant neoplasm of periosteum
Excludes1: malignant neoplasm of bone marrow NOS (C96.8)
malignant neoplasm of synovia (C49.-)

C40 Malignant neoplasm of bone and articular cartilage of limbs[edit]

Use additional code to identify major osseous defect, if applicable (M89.7-)
C40.0 Malignant neoplasm of scapula and long bones of upper limb
C40.00 Malignant neoplasm of scapula and long bones of upper limb, unspecified side
C40.01 Malignant neoplasm of scapula and long bones of right upper limb
C40. 02 Malignant neoplasm of scapula and long bones of left upper limb
C40.1 Malignant neoplasm of short bones of upper limb
C40.10 Malignant neoplasm of short bones of upper limb, unspecified side
C40.11 Malignant neoplasm of short bones of right upper limb
C40.12 Malignant neoplasm of short bones of left upper limb
C40.2 Malignant neoplasm of long bones of lower limb
C40.20 Malignant neoplasm of long bones of lower limb, unspecified side
C40.21 Malignant neoplasm of long bones of right lower limb
C40.22 Malignant neoplasm of long bones of left lower limb
C40.3 Malignant neoplasm of short bones of lower limb
C40.30 Malignant neoplasm of short bones of lower limb, unspecified side
C40.31 Malignant neoplasm of short bones of right lower limb
C40.32 Malignant neoplasm of short bones of left lower limb
C40.8 Malignant neoplasm of overlapping sites of bone and articular cartilage of limb
C40.80 Malignant neoplasm of overlapping sites of bone and articular cartilage of limb, unspecified side
C40.81 Malignant neoplasm of overlapping sites of bone and articular cartilage of right limb
C40.82 Malignant neoplasm of overlapping sites of bone and articular cartilage of left limb
C40.9 Malignant neoplasm of bones and articular cartilage of limb, unspecified
C40.90 Malignant neoplasm of bones and articular cartilage of limb, unspecified, unspecified side
C40.91 Malignant neoplasm of bones and articular cartilage of right limb, unspecified
C40.92 Malignant neoplasm of bones and articular cartilage of left limb, unspecified

C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites[edit]

Excludes1: malignant neoplasm of bones of limbs (C40.-)
malignant neoplasm of cartilage of:
ear (C49.0)
eyelid (C49.0)
larynx (C32.3)
limbs (C40.-)
nose (C30.0)
C41.0 Malignant neoplasm of bones of skull and face
Malignant neoplasm of maxilla (superior)
Malignant neoplasm of orbital bone
Excludes2: carcinoma, any type except intraosseous or odontogenic of:
maxillary sinus (C31.0)
upper jaw (C03.0)
malignant neoplasm of jaw bone (lower) (C41.1)
C41.1 Malignant neoplasm of mandible
Malignant neoplasm of inferior maxilla
Malignant neoplasm of lower jaw bone
Excludes2: carcinoma, any type except intraosseous or odontogenic of:
jaw NOS (C03.9)
lower (C03.1)
malignant neoplasm of upper jaw bone (C41.0)
C41.2 Malignant neoplasm of vertebral column
Excludes1: malignant neoplasm of sacrum and coccyx (C41.4)
C41.3 Malignant neoplasm of ribs, sternum and clavicle
C41.4 Malignant neoplasm of pelvic bones, sacrum and coccyx
C41.9 Malignant neoplasm of bone and articular cartilage, unspecified

Melanoma and other malignant neoplasms of skin (C43-C44)[edit]

C43 Malignant melanoma of skin[edit]

Excludes1: melanoma in situ (D03.-)
Excludes2: malignant melanoma of skin of genital organs (C51-C52, C60.-, C63.-)
Merkel cell carcinoma (C4a.-)
sites other than skin-code to malignant neoplasm of the site
C43.0 Malignant melanoma of lip
Excludes1: malignant neoplasm of vermilion border of lip (C00.0-C00.2)
C43.1 Malignant melanoma of eyelid, including canthus
C43.10 Malignant melanoma of eyelid, including canthus, unspecified side
C43.11 Malignant melanoma of right eyelid, including canthus
C43.12 Malignant melanoma of left eyelid, including canthus
C43.2 Malignant melanoma of ear and external auricular canal
C43.20 Malignant melanoma of ear and external auricular canal, unspecified side
C43.21 Malignant melanoma of right ear and external auricular canal
C43.22 Malignant melanoma of left ear and external auricular canal
C43.3 Malignant melanoma of other and unspecified parts of face
C43.30 Malignant melanoma of unspecified part of face
C43.31 Malignant melanoma of nose
C43.39 Malignant melanoma of other parts of face
C43.4 Malignant melanoma of scalp and neck
C43. 5 Malignant melanoma of trunk
Excludes2: malignant neoplasm of anus NOS (C21.0)
malignant neoplasm of scrotum (C63.2)
C43.51 Malignant melanoma of anal skin
Malignant melanoma of anal margin
Malignant melanoma of perianal skin
C43.52 Malignant melanoma of skin of breast
C43.59 Malignant melanoma of other part of trunk
C43.6 Malignant melanoma of upper limb, including shoulder
C43.60 Malignant melanoma of upper limb, including shoulder, unspecified side
C43.61 Malignant melanoma of right upper limb, including shoulder
C43.62 Malignant melanoma of left upper limb, including shoulder
C43.7 Malignant melanoma of lower limb, including hip
C43.70 Malignant melanoma of lower limb, including hip, unspecified side
C43.71 Malignant melanoma of right lower limb, including hip
C43.72 Malignant melanoma of left lower limb, including hip
C43.8 Overlapping malignant melanoma of skin
C43.9 Malignant melanoma of skin, unspecified
Melanoma (malignant) NOS

C4a Merkel cell carcinoma[edit]

C4a.0 Merkel cell carcinoma of lip
Excludes1: malignant neoplasm of vermilion border of lip (C00.0-C00.2)
C4a.1 Merkel cell carcinoma of eyelid, including canthus
C4a.10 Merkel cell carcinoma of eyelid, including canthus, unspecified side
C4a.11 Merkel cell carcinoma of right eyelid, including canthus
C4a.12 Merkel cell carcinoma of left eyelid, including canthus
C4a.2 Merkel cell carcinoma of ear and external auricular canal
C4a.20 Merkel cell carcinoma of ear and external auricular canal, unspecified side
C4a.21 Merkel cell carcinoma of right ear and external auricular canal
C4a.22 Merkel cell carcinoma of left ear and external auricular canal
C4a.3 Merkel cell carcinoma of other and unspecified parts of face
C4a.30 Merkel cell carcinoma of unspecified part of face
C4a.31 Merkel cell carcinoma of nose
C4a.39 Merkel cell carcinoma of other parts of face
C4a.4 Merkel cell carcinoma of scalp and neck
C4a.5 Merkel cell carcinoma of trunk
Excludes2: malignant neoplasm of anus NOS (C21.0)
malignant neoplasm of scrotum (C63.2)
C4a.51 Merkel cell carcinoma of anal skin
Merkel cell carcinoma of anal margin
Merkel cell carcinoma of perianal skin
C4a.52 Merkel cell carcinoma of skin of breast
C4a.59 Merkel cell carcinoma of other part of trunk
C4a.6 Merkel cell carcinoma of upper limb, including shoulder
C4a.60 Merkel cell carcinoma of upper limb, including shoulder, unspecified side
C4a.61 Merkel cell carcinoma of right upper limb, including shoulder
C4a.62 Merkel cell carcinoma of left upper limb, including shoulder
C4a.7 Merkel cell carcinoma of lower limb, including hip
C4a.70 Merkel cell carcinoma of lower limb, including hip, unspecified side
C4a.71 Merkel cell carcinoma of right lower limb, including hip
C4a.72 Merkel cell carcinoma of left lower limb, including hip
C4a.8 Merkel cell carcinoma of overlapping sites
C4a.9 Merkel cell carcinoma, unspecified
Merkel cell carcinoma NOS

C44 Other malignant neoplasm of skin[edit]

Includes: malignant neoplasm of sebaceous glands
malignant neoplasm of sweat glands
Excludes1: Kaposi's sarcoma of skin (C46.0)
malignant melanoma of skin (C43.-)
malignant neoplasm of skin of genital organs (C51-C52, C60.-, C63.2)
Merkel cell carcinoma (C4a.-)
C44.0 Malignant neoplasm of skin of lip
Malignant neoplasm of basal cell carcinoma of lip
Excludes1: malignant neoplasm of lip (C00.-)
C44.1 Malignant neoplasm of skin of eyelid, including canthus
Excludes1: connective tissue of eyelid (C49.0)
C44.10 Malignant neoplasm of skin of eyelid, including canthus, unspecified side
C44.11 Malignant neoplasm of skin of right eyelid, including canthus
C44.12 Malignant neoplasm of skin of left eyelid, including canthus
C44.2 Malignant neoplasm of skin of ear and external auricular canal
Excludes1: connective tissue of ear (C49.0)
C44.20 Malignant neoplasm of skin of ear and external auricular canal, unspecified side
C44.21 Malignant neoplasm of skin of right ear and external auricular canal
C44. 22 Malignant neoplasm of skin of left ear and external auricular canal
C44.3 Malignant neoplasm of skin of other and unspecified parts of face
C44.30 Malignant neoplasm of skin of unspecified part of face
C44.31 Malignant neoplasm of skin of nose
C44.39 Malignant neoplasm of skin of other parts of face
C44.4 Malignant neoplasm of skin of scalp and neck
C44.5 Malignant neoplasm of skin of trunk
Excludes1: anus NOS (C21.0)
scrotum (C63.2)
C44.51 Malignant neoplasm of anal skin
Malignant neoplasm of anal margin
Malignant neoplasm of perianal skin
C44.52 Malignant neoplasm of skin of breast
C44.59 Malignant neoplasm of other part of trunk
C44.6 Malignant neoplasm of skin of upper limb, including shoulder
C44.60 Malignant neoplasm of skin of upper limb, including shoulder, unspecified side
C44.61 Malignant neoplasm of skin of right upper limb, including shoulder
C44.62 Malignant neoplasm of skin of left upper limb, including shoulder
C44.7 Malignant neoplasm of skin of lower limb, including hip
C44.70 Malignant neoplasm of skin of lower limb, including hip, unspecified side
C44.71 Malignant neoplasm of skin of right lower limb, including hip
C44.72 Malignant neoplasm of skin of left lower limb, including hip
C44.8 Malignant neoplasm of overlapping sites of skin
C44.9 Malignant neoplasm of skin, unspecified

Malignant neoplasms of mesothelial and soft tissue (C45-C49)[edit]

C45 Mesothelioma[edit]

C45.0 Mesothelioma of pleura
Excludes1: other malignant neoplasm of pleura (C38.4)
C45.1 Mesothelioma of peritoneum
Mesothelioma of cul-de-sac
Mesothelioma of mesentery
Mesothelioma of mesocolon
Mesothelioma of omentum
Mesothelioma of peritoneum (parietal) (pelvic)
Excludes1: other malignant neoplasm of soft tissue of peritoneum (C48.-)
C45.2 Mesothelioma of pericardium
Excludes1: other malignant neoplasm of pericardium (C38.0)
C45.7 Mesothelioma of other sites
C45.9 Mesothelioma, unspecified

C46 Kaposi's sarcoma[edit]

Code first any human immunodeficiency virus [HIV] disease (B20)
C46.0 Kaposi's sarcoma of skin
C46.1 Kaposi's sarcoma of soft tissue
Kaposi's sarcoma of blood vessel
Kaposi's sarcoma of connective tissue
Kaposi's sarcoma of fascia
Kaposi's sarcoma of ligament
Kaposi's sarcoma of lymphatic(s) NEC
Kaposi's sarcoma of muscle
Excludes2: Kaposi's sarcoma of lymph glands and nodes (C46.3)
C46.2 Kaposi's sarcoma of palate
C46.3 Kaposi's sarcoma of lymph nodes
C46.4 Kaposi's sarcoma of gastrointestinal sites
C46.5 Kaposi's sarcoma of lung
C46.50 Kaposi's sarcoma of lung, unspecified side
C46.51 Kaposi's sarcoma of right lung
C46.52 Kaposi's sarcoma of left lung
C46.7 Kaposi's sarcoma of other sites
C46.9 Kaposi's sarcoma, unspecified

C47 Malignant neoplasm of peripheral nerves and autonomic nervous system[edit]

Includes: malignant neoplasm of sympathetic and parasympathetic nerves and ganglia
Excludes1: Kaposi's sarcoma of soft tissue (C46.1)
C47.0 Malignant neoplasm of peripheral nerves of head, face and neck
Excludes1: malignant neoplasm of peripheral nerves of orbit (C69.6-)
C47.1 Malignant neoplasm of peripheral nerves of upper limb, including shoulder
C47.10 Malignant neoplasm of peripheral nerves of upper limb, including shoulder, unspecified side
C47.11 Malignant neoplasm of peripheral nerves of right upper limb, including shoulder
C47.12 Malignant neoplasm of peripheral nerves of left upper limb, including shoulder
C47.2 Malignant neoplasm of peripheral nerves of lower limb, including hip
C47.20 Malignant neoplasm of peripheral nerves of lower limb, including hip, unspecified side
C47. 21 Malignant neoplasm of peripheral nerves of right lower limb, including hip
C47.22 Malignant neoplasm of peripheral nerves of left lower limb, including hip
C47.3 Malignant neoplasm of peripheral nerves of thorax
C47.4 Malignant neoplasm of peripheral nerves of abdomen
C47.5 Malignant neoplasm of peripheral nerves of pelvis
C47.6 Malignant neoplasm of peripheral nerves of trunk, unspecified
C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system
C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified

C48 Malignant neoplasm of retroperitoneum and peritoneum[edit]

Excludes1: Kaposi's sarcoma of connective tissue (C46.1)
mesothelioma (C45.-)
C48.0 Malignant neoplasm of retroperitoneum
C48.1 Malignant neoplasm of specified parts of peritoneum
Malignant neoplasm of cul-de-sac
Malignant neoplasm of mesentery
Malignant neoplasm of mesocolon
Malignant neoplasm of omentum
Malignant neoplasm of parietal peritoneum
Malignant neoplasm of pelvic peritoneum
C48.2 Malignant neoplasm of peritoneum, unspecified
C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum

C49 Malignant neoplasm of other connective and soft tissue[edit]

Includes: malignant neoplasm of blood vessel
malignant neoplasm of bursa
malignant neoplasm of cartilage
malignant neoplasm of fascia
malignant neoplasm of fat
malignant neoplasm of ligament, except uterine
malignant neoplasm of lymphatic vessel
malignant neoplasm of muscle
malignant neoplasm of synovia
malignant neoplasm of tendon (sheath)
Excludes1: malignant neoplasm of cartilage (of):
articular (C40-C41)
larynx (C32.3)
nose (C30.0)
malignant neoplasm of connective tissue of internal organs -code to malignant neoplasm of the site
malignant stromal tumors-code to malignant neoplasm of the site
Excludes2: Kaposi's sarcoma of soft tissue (C46.1)
malignant neoplasm of heart (C38.0)
malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
malignant neoplasm of peritoneum (C48.2)
malignant neoplasm of retroperitoneum (C48.0)
malignant neoplasm of uterine ligament (C57.3)
mesothelioma (C45.-)
C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck
Malignant neoplasm of connective tissue of ear
Malignant neoplasm of connective tissue of eyelid
Excludes1: connective tissue of orbit (C69.6-)
C49.1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder
C49.10 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder, unspecified side
C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder
C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip
C49.20 Malignant neoplasm of connective and soft tissue of lower limb, including hip, unspecified side
C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip
C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip
C49.3 Malignant neoplasm of connective and soft tissue of thorax
Malignant neoplasm of axilla
Malignant neoplasm of diaphragm
Malignant neoplasm of great vessels
Excludes1: malignant neoplasm of breast (C50.-)
malignant neoplasm of heart (C38.0)
malignant neoplasm of mediastinum (C38.1-C38.3)
malignant neoplasm of thymus (C37)
C49.4 Malignant neoplasm of connective and soft tissue of abdomen
Malignant neoplasm of abdominal wall
Malignant neoplasm of hypochondrium
C49.5 Malignant neoplasm of connective and soft tissue of pelvis
Malignant neoplasm of buttock
Malignant neoplasm of groin
Malignant neoplasm of perineum
C49.6 Malignant neoplasm of connective and soft tissue of trunk, unspecified
Malignant neoplasm of back NOS
C49. 8 Malignant neoplasm of overlapping sites of connective and soft tissue
Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue
C49.9 Malignant neoplasm of connective and soft tissue, unspecified

Malignant neoplasm of breast (C50)[edit]

C50 Malignant neoplasm of breast[edit]

Includes: connective tissue of breast
Paget's disease of breast
Paget's disease of nipple
Use additional code to identify estrogen receptor status (Z17.0, Z17.1)
Excludes1: skin of breast (C43.5, C44.5)
C50.0 Malignant neoplasm of nipple and areola
C50.01 Malignant neoplasm of nipple and areola, female
C50.011 Malignant neoplasm of nipple and areola, right female breast
C50.012 Malignant neoplasm of nipple and areola, left female breast
C50.019 Malignant neoplasm of nipple and areola, unspecified female breast
C50.02 Malignant neoplasm of nipple and areola, male
C50.021 Malignant neoplasm of nipple and areola, right male breast
C50.022 Malignant neoplasm of nipple and areola, left male breast
C50.029 Malignant neoplasm of nipple and areola, unspecified male breast
C50.1 Malignant neoplasm of central portion of breast
C50.11 Malignant neoplasm of central portion of breast, female
C50.111 Malignant neoplasm of central portion of right female breast
C50.112 Malignant neoplasm of central portion of left female breast
C50.119 Malignant neoplasm of central portion of unspecified female breast
C50.12 Malignant neoplasm of central portion of breast, male
C50.121 Malignant neoplasm of central portion of right male breast
C50.122 Malignant neoplasm of central portion of left male breast
C50.129 Malignant neoplasm of central portion of unspecified male breast
C50. 2 Malignant neoplasm of upper-inner quadrant of breast
C50.21 Malignant neoplasm of upper-inner quadrant of breast, female
C50.211 Malignant neoplasm of upper-inner quadrant of right female breast
C50.212 Malignant neoplasm of upper-inner quadrant of left female breast
C50.219 Malignant neoplasm of upper-inner quadrant of unspecified female breast
C50.22 Malignant neoplasm of upper-inner quadrant of breast, male
C50.221 Malignant neoplasm of upper-inner quadrant of right male breast
C50.222 Malignant neoplasm of upper-inner quadrant of left male breast
C50.229 Malignant neoplasm of upper-inner quadrant of unspecified male breast
C50.3 Malignant neoplasm of lower-inner quadrant of breast
C50.31 Malignant neoplasm of lower-inner quadrant of breast, female
C50.311 Malignant neoplasm of lower-inner quadrant of right female breast
C50.312 Malignant neoplasm of lower-inner quadrant of left female breast
C50.319 Malignant neoplasm of lower-inner quadrant of unspecified female breast
C50.32 Malignant neoplasm of lower-inner quadrant of breast, male
C50.321 Malignant neoplasm of lower-inner quadrant of right male breast
C50.322 Malignant neoplasm of lower-inner quadrant of left male breast
C50.329 Malignant neoplasm of lower-inner quadrant of unspecified male breast
C50.4 Malignant neoplasm of upper-outer quadrant of breast
C50.41 Malignant neoplasm of upper-outer quadrant of breast, female
C50.411 Malignant neoplasm of upper-outer quadrant of right female breast
C50.412 Malignant neoplasm of upper-outer quadrant of left female breast
C50.419 Malignant neoplasm of upper-outer quadrant of unspecified female breast
C50.42 Malignant neoplasm of upper-outer quadrant of breast, male
C50. 421 Malignant neoplasm of upper-outer quadrant of right male breast
C50.422 Malignant neoplasm of upper-outer quadrant of left male breast
C50.429 Malignant neoplasm of upper-outer quadrant of unspecified male breast
C50.5 Malignant neoplasm of lower-outer quadrant of breast
C50.51 Malignant neoplasm of lower-outer quadrant of breast, female
C50.511 Malignant neoplasm of lower-outer quadrant of right female breast
C50.512 Malignant neoplasm of lower-outer quadrant of left female breast
C50.519 Malignant neoplasm of lower-outer quadrant of unspecified female breast
C50.52 Malignant neoplasm of lower-outer quadrant of breast, male
C50.521 Malignant neoplasm of lower-outer quadrant of right male breast
C50.522 Malignant neoplasm of lower-outer quadrant of left male breast
C50.529 Malignant neoplasm of lower-outer quadrant of unspecified male breast
C50.6 Malignant neoplasm of axillary tail of breast
C50.61 Malignant neoplasm of axillary tail of breast, female
C50.611 Malignant neoplasm of axillary tail of right female breast
C50.612 Malignant neoplasm of axillary tail of left female breast
C50.619 Malignant neoplasm of axillary tail of unspecified female breast
C50.62 Malignant neoplasm of axillary tail of breast, male
C50.621 Malignant neoplasm of axillary tail of right male breast
C50.622 Malignant neoplasm of axillary tail of left male breast
C50.629 Malignant neoplasm of axillary tail of unspecified male breast
C50.8 Malignant neoplasm of overlapping sites of breast
C50.81 Malignant neoplasm of overlapping sites of breast, female
C50.811 Malignant neoplasm of overlapping sites of right female breast
C50.812 Malignant neoplasm of overlapping sites of left female breast
C50. 819 Malignant neoplasm of overlapping sites of unspecified female breast
C50.82 Malignant neoplasm of overlapping sites of breast, male
C50.821 Malignant neoplasm of overlapping sites of right male breast
C50.822 Malignant neoplasm of overlapping sites of left male breast
C50.829 Malignant neoplasm of overlapping sites of unspecified male breast
C50.9 Malignant neoplasm of breast of unspecified site
C50.91 Malignant neoplasm of breast of unspecified site, female
C50.911 Malignant neoplasm of unspecified site of right female breast
C50.912 Malignant neoplasm of unspecified site of left female breast
C50.919 Malignant neoplasm of unspecified site of unspecified female breast
C50.92 Malignant neoplasm of breast of unspecified site, male
C50.921 Malignant neoplasm of unspecified site of right male breast
C50.922 Malignant neoplasm of unspecified site of left male breast
C50.929 Malignant neoplasm of unspecified site of unspecified male breast

Malignant neoplasm of female genital organs (C51-C58)[edit]

Includes: malignant neoplasm of skin of female genital organs

C51 Malignant neoplasm of vulva[edit]

Excludes1: carcinoma in situ of vulva (D07.1)
C51.0 Malignant neoplasm of labium majus
Malignant neoplasm of Bartholin's [greater vestibular] gland
C51.1 Malignant neoplasm of labium minus
C51.2 Malignant neoplasm of clitoris
C51.8 Malignant neoplasm of overlapping sites of vulva
C51.9 Malignant neoplasm of vulva, unspecified
Malignant neoplasm of external female genitalia NOS
Malignant neoplasm of pudendum

C52 Malignant neoplasm of vagina[edit]

Excludes1: carcinoma in situ of vagina (D07.2)

C53 Malignant neoplasm of cervix uteri[edit]

Excludes1: carcinoma in situ of cervix uteri (D06.-)
C53. 0 Malignant neoplasm of endocervix
C53.1 Malignant neoplasm of exocervix
C53.8 Malignant neoplasm of overlapping sites of cervix uteri
C53.9 Malignant neoplasm of cervix uteri, unspecified

C54 Malignant neoplasm of corpus uteri[edit]

C54.0 Malignant neoplasm of isthmus uteri
Malignant neoplasm of lower uterine segment
C54.1 Malignant neoplasm of endometrium
C54.2 Malignant neoplasm of myometrium
C54.3 Malignant neoplasm of fundus uteri
C54.8 Malignant neoplasm of overlapping sites of corpus uteri
C54.9 Malignant neoplasm of corpus uteri, unspecified

C55 Malignant neoplasm of uterus, part unspecified[edit]

C56 Malignant neoplasm of ovary[edit]

Use additional code to identify any functional activity
C56.0 Malignant neoplasm of right ovary
C56.1 Malignant neoplasm of left ovary
C56.9 Malignant neoplasm of ovary, unspecified side

C57 Malignant neoplasm of other and unspecified female genital organs[edit]

C57.0 Malignant neoplasm of fallopian tube
Malignant neoplasm of oviduct
Malignant neoplasm of uterine tube
C57.00 Malignant neoplasm of fallopian tube, unspecified side
C57.01 Malignant neoplasm of right fallopian tube
C57.02 Malignant neoplasm of left fallopian tube
C57.1 Malignant neoplasm of broad ligament
C57.10 Malignant neoplasm of broad ligament, unspecified side
C57.11 Malignant neoplasm of right broad ligament
C57.12 Malignant neoplasm of left broad ligament
C57.2 Malignant neoplasm of round ligament
C57.20 Malignant neoplasm of round ligament, unspecified side
C57.21 Malignant neoplasm of right round ligament
C57.22 Malignant neoplasm of left round ligament
C57.3 Malignant neoplasm of parametrium
Malignant neoplasm of uterine ligament NOS
C57.4 Malignant neoplasm of uterine adnexa, unspecified
C57.7 Malignant neoplasm of other specified female genital organs
Malignant neoplasm of wolffian body or duct
C57.8 Malignant neoplasm of overlapping sites of female genital organs
Primary malignant neoplams of two or more contiguous sites of the female genital organs whose point of origin cannot be determined
Primary tubo-ovarian malignant neoplasm whose point of origin cannot be determined
Primary utero-ovarian malignant neoplasm whose point of origin cannot be determined
C57.9 Malignant neoplasm of female genital organ, unspecified
Malignant neoplasm of female genitourinary tract NOS

C58 Malignant neoplasm of placenta[edit]

Includes: choriocarcinoma NOS
chorionepithelioma NOS
Excludes1: chorioadenoma (destruens) (D39.2)
hydatidiform mole NOS (O01.9)
invasive hydatidiform mole (D39.2)
male choriocarcinoma NOS (C62.9-)
malignant hydatidiform mole (D39.2)

Malignant neoplasms of male genital organs (C60-C63)[edit]

Includes: malignant neoplasm of skin of male genital organs

C60 Malignant neoplasm of penis[edit]

C60.0 Malignant neoplasm of prepuce
Malignant neoplasm of foreskin
C60.1 Malignant neoplasm of glans penis
C60.2 Malignant neoplasm of body of penis
Malignant neoplasm of corpus cavernosum
C60.8 Malignant neoplasm of overlapping sites of penis
C60.9 Malignant neoplasm of penis, unspecified
Malignant neoplasm of skin of penis NOS

C61 Malignant neoplasm of prostate[edit]

Excludes1: malignant neoplasm of seminal vesicle (C63.7)

C62 Malignant neoplasm of testis[edit]

Use additional code to identify any functional activity.
C62.0 Malignant neoplasm of undescended testis
Malignant neoplasm of ectopic testis
Malignant neoplasm of retained testis
C62.00 Malignant neoplasm of undescended testis, unspecified side
C62.01 Malignant neoplasm of undescended right testis
C62.02 Malignant neoplasm of undescended left testis
C62.1 Malignant neoplasm of descended testis
Malignant neoplasm of scrotal testis
C62. 10 Malignant neoplasm of descended testis, unspecified side
C62.11 Malignant neoplasm of descended right testis
C62.12 Malignant neoplasm of descended left testis
C62.9 Malignant neoplasm of testis, unspecified
C62.90 Malignant neoplasm of testis, unspecified, unspecified side
C62.91 Malignant neoplasm of right testis, unspecified
C62.92 Malignant neoplasm of left testis, unspecified

C63 Malignant neoplasm of other and unspecified male genital organs[edit]

C63.0 Malignant neoplasm of epididymis
C63.00 Malignant neoplasm of epididymis, unspecified side
C63.01 Malignant neoplasm of right epididymis
C63.02 Malignant neoplasm of left epididymis
C63.1 Malignant neoplasm of spermatic cord
C63.10 Malignant neoplasm of spermatic cord, unspecified side
C63.11 Malignant neoplasm of right spermatic cord
C63.12 Malignant neoplasm of left spermatic cord
C63.2 Malignant neoplasm of scrotum
Malignant neoplasm of skin of scrotum
C63.7 Malignant neoplasm of other specified male genital organs
Malignant neoplasm of seminal vesicle
Malignant neoplasm of tunica vaginalis
C63.8 Malignant neoplasm of overlapping sites of male genital organs
Primary malignant neoplasm of two or more contiguous sites of male genital organs whose point of origin cannot be determined
C63.9 Malignant neoplasm of male genital organ, unspecified
Malignant neoplasm of male genitourinary tract NOS

Malignant neoplasm of urinary tract (C64-C68)[edit]

C64 Malignant neoplasm of kidney, except renal pelvis[edit]

Excludes1: malignant carcinoid tumor of the kidney (C7a.093)
malignant neoplasm of renal calyces (C65.-)
malignant neoplasm of renal pelvis (C65.-)
C64.0 Malignant neoplasm of right kidney, except renal pelvis
C64.1 Malignant neoplasm of left kidney, except renal pelvis
C64.9 Malignant neoplasm of kidney, except renal pelvis, unspecified side

C65 Malignant neoplasm of renal pelvis[edit]

Includes: malignant neoplasm of pelviureteric junction
malignant neoplasm of renal calyces
C65.0 Malignant neoplasm of right renal pelvis
C65.1 Malignant neoplasm of left renal pelvis
C65.9 Malignant neoplasm of renal pelvis, unspecified side

C66 Malignant neoplasm of ureter[edit]

Excludes1: malignant neoplasm of ureteric orifice of bladder (C67.6)
C66.0 Malignant neoplasm of right ureter
C66.1 Malignant neoplasm of left ureter
C66.9 Malignant neoplasm of ureter, unspecified side

C67 Malignant neoplasm of bladder[edit]

C67.0 Malignant neoplasm of trigone of bladder
C67.1 Malignant neoplasm of dome of bladder
C67.2 Malignant neoplasm of lateral wall of bladder
C67.3 Malignant neoplasm of anterior wall of bladder
C67.4 Malignant neoplasm of posterior wall of bladder
C67.5 Malignant neoplasm of bladder neck
Malignant neoplasm of internal urethral orifice
C67.6 Malignant neoplasm of ureteric orifice
C67.7 Malignant neoplasm of urachus
C67.8 Malignant neoplasm of overlapping sites of bladder
C67.9 Malignant neoplasm of bladder, unspecified

C68 Malignant neoplasm of other and unspecified urinary organs[edit]

Excludes1: malignant neoplasm of female genitourinary tract NOS (C57.9)
malignant neoplasm of male genitourinary tract NOS (C63.9)
C68.0 Malignant neoplasm of urethra
Excludes1: malignant neoplasm of urethral orifice of bladder (C67.5)
C68.1 Malignant neoplasm of paraurethral glands
C68.8 Malignant neoplasm of overlapping sites of urinary organs
Primary malignant neoplasm of two or more contiguous sites of urinary organs whose point of origin cannot be determined
C68.9 Malignant neoplasm of urinary organ, unspecified
Malignant neoplasm of urinary system NOS

Malignant neoplasms of eye, brain and other parts of central nervous system (C69-C72)[edit]

C69 Malignant neoplasm of eye and adnexa[edit]

Excludes1: malignant neoplasm of connective tissue of eyelid (C49.0)
malignant neoplasm of eyelid (skin) (C43.1-, C44.1-)
malignant neoplasm of optic nerve (C72.3-)
C69.0 Malignant neoplasm of conjunctiva
C69. 00 Malignant neoplasm of conjunctiva, unspecified side
C69.01 Malignant neoplasm of right conjunctiva
C69.02 Malignant neoplasm of left conjunctiva
C69.1 Malignant neoplasm of cornea
C69.10 Malignant neoplasm of cornea, unspecified side
C69.11 Malignant neoplasm of right cornea
C69.12 Malignant neoplasm of left cornea
C69.2 Malignant neoplasm of retina
Excludes1: dark area on retina (D49.81)
neoplasm of unspecified behavior of retina and choroid (D49.81)
retinal freckle (D49.81)
C69.20 Malignant neoplasm of retina, unspecified side
C69.21 Malignant neoplasm of right retina
C69.22 Malignant neoplasm of left retina
C69.3 Malignant neoplasm of choroid
C69.30 Malignant neoplasm of choroid, unspecified side
C69.31 Malignant neoplasm of right choroid
C69.32 Malignant neoplasm of left choroid
C69.4 Malignant neoplasm of ciliary body
Malignant neoplasm of eyeball
C69.40 Malignant neoplasm of ciliary body, unspecified side
C69.41 Malignant neoplasm of right ciliary body
C69.42 Malignant neoplasm of left ciliary body
C69.5 Malignant neoplasm of lacrimal gland and duct
Malignant neoplasm of lacrimal sac
Malignant neoplasm of nasolacrimal duct
C69.50 Malignant neoplasm of lacrimal gland and duct, unspecified side
C69.51 Malignant neoplasm of right lacrimal gland and duct
C69.52 Malignant neoplasm of left lacrimal gland and duct
C69.6 Malignant neoplasm of orbit
Malignant neoplasm of connective tissue of orbit
Malignant neoplasm of extraocular muscle
Malignant neoplasm of peripheral nerves of orbit
Malignant neoplasm of retrobulbar tissue
Malignant neoplasm of retro-ocular tissue
Excludes1: malignant neoplasm of orbital bone (C41.0)
C69.60 Malignant neoplasm of orbit, unspecified side
C69.61 Malignant neoplasm of right orbit
C69.62 Malignant neoplasm of left orbit
C69.8 Malignant neoplasm of overlapping sites of eye and adnexa
C69.80 Malignant neoplasm of overlapping sites of eye and adnexa, unspecified side
C69.81 Malignant neoplasm of overlapping sites of right eye and adnexa
C69. 82 Malignant neoplasm of overlapping sites of left eye and adnexa
C69.9 Malignant neoplasm of eye, unspecified
C69.90 Malignant neoplasm of eye, unspecified, unspecified side
C69.91 Malignant neoplasm of right eye, unspecified
C69.92 Malignant neoplasm of left eye, unspecified

C70 Malignant neoplasm of meninges[edit]

C70.0 Malignant neoplasm of cerebral meninges
C70.1 Malignant neoplasm of spinal meninges
C70.9 Malignant neoplasm of meninges, unspecified

C71 Malignant neoplasm of brain[edit]

Excludes1: malignant neoplasm of cranial nerves (C72.2-C72.5)
retrobulbar malignant neoplasm (C69.6-)
C71.0 Malignant neoplasm of cerebrum, except lobes and ventricles
Malignant neoplasm of supratentorial NOS
C71.1 Malignant neoplasm of frontal lobe
C71.2 Malignant neoplasm of temporal lobe
C71.3 Malignant neoplasm of parietal lobe
C71.4 Malignant neoplasm of occipital lobe
C71.5 Malignant neoplasm of cerebral ventricle
Excludes1: malignant neoplasm of fourth cerebral ventricle (C71.7)
C71.6 Malignant neoplasm of cerebellum
C71.7 Malignant neoplasm of brain stem
Malignant neoplasm of fourth cerebral ventricle
Infratentorial malignant neoplasm NOS
C71.8 Malignant neoplasm of overlapping sites of brain
C71.9 Malignant neoplasm of brain, unspecified

C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system[edit]

Excludes1: malignant neoplasm of meninges (C70.-)
malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
C72.0 Malignant neoplasm of spinal cord
C72.1 Malignant neoplasm of cauda equina
C72.2 Malignant neoplasm of olfactory nerve
Malignant neoplasm of olfactory bulb
C72.20 Malignant neoplasm of olfactory nerve, unspecified side
C72.21 Malignant neoplasm of right olfactory nerve
C72.22 Malignant neoplasm of left olfactory nerve
C72.3 Malignant neoplasm of optic nerve
C72.30 Malignant neoplasm of optic nerve, unspecified side
C72.31 Malignant neoplasm of right optic nerve
C72. 32 Malignant neoplasm of left optic nerve
C72.4 Malignant neoplasm of acoustic nerve
C72.40 Malignant neoplasm of acoustic nerve, unspecified side
C72.41 Malignant neoplasm of right acoustic nerve
C72.42 Malignant neoplasm of left acoustic nerve
C72.5 Malignant neoplasm of other and unspecified cranial nerves
C72.50 Malignant neoplasm of unspecified cranial nerve
Malignant neoplasm of cranial nerve NOS
C72.59 Malignant neoplasm of other cranial nerves
C72.9 Malignant neoplasm of central nervous system, unspecified
Malignant neoplasm of nervous system NOS

Malignant neoplasm of thyroid and other endocrine glands (C73-C75)[edit]

C73 Malignant neoplasm of thyroid gland[edit]

Use additional code to identify any functional activity

C74 Malignant neoplasm of adrenal gland[edit]

C74.0 Malignant neoplasm of cortex of adrenal gland
C74.00 Malignant neoplasm of cortex of adrenal gland, unspecified side
C74.01 Malignant neoplasm of cortex of right adrenal gland
C74.02 Malignant neoplasm of cortex of left adrenal gland
C74.1 Malignant neoplasm of medulla of adrenal gland
C74.10 Malignant neoplasm of medulla of adrenal gland, unspecified side
C74.11 Malignant neoplasm of medulla of right adrenal gland
C74.12 Malignant neoplasm of medulla of left adrenal gland
C74.9 Malignant neoplasm of adrenal gland, unspecified
C74.90 Malignant neoplasm of adrenal gland, unspecified, unspecified side
C74.91 Malignant neoplasm of right adrenal gland, unspecified
C74.92 Malignant neoplasm of left adrenal gland, unspecified

C75 Malignant neoplasm of other endocrine glands and related structures[edit]

Excludes1: malignant carcinoid tumors (C7a.0-)
malignant neoplasm of adrenal gland (C74.-)
malignant neoplasm of endocrine pancreas (C25.4)
malignant neoplasm of islets of Langerhans (C25.4)
malignant neoplasm of ovary (C56-)
malignant neoplasm of testis (C62.-)
malignant neoplasm of thymus (C37)
malignant neoplasm of thyroid gland (C73)
malignant neuroendocrine tumors (C7a.-)
C75.0 Malignant neoplasm of parathyroid gland
C75.1 Malignant neoplasm of pituitary gland
C75.2 Malignant neoplasm of craniopharyngeal duct
C75.3 Malignant neoplasm of pineal gland
C75.4 Malignant neoplasm of carotid body
C75.5 Malignant neoplasm of aortic body and other paraganglia
C75.8 Malignant neoplasm with pluriglandular involvement, unspecified
C75.9 Malignant neoplasm of endocrine gland, unspecified

Malignant neuroendocrine tumors (C7a)[edit]

C7a Malignant neuroendocrine tumors[edit]

Code also any associated multiple endocrine neoplasia [MEN] syndromes (E31.2-)
Use additional code to identify any associated endocrine syndrome, such as:
carcinoid syndrome (E34.0)
Excludes2: malignant pancreatic islet cell tumors (C25.4)
Merkel cell carcinoma (C4a.-)
C7a.0 Malignant carcinoid tumors
C7a.00 Malignant carcinoid tumor of unspecified site
C7a.01 Malignant carcinoid tumors of the small intestine
C7a.010 Malignant carcinoid tumor of the duodenum
C7a.011 Malignant carcinoid tumor of the jejunum
C7a.012 Malignant carcinoid tumor of the ileum
C7a.019 Malignant carcinoid tumor of the small intestine, unspecified portion
C7a.02 Malignant carcinoid tumors of the appendix, large intestine, and rectum
C7a.020 Malignant carcinoid tumor of the appendix
C7a.021 Malignant carcinoid tumor of the cecum
C7a.022 Malignant carcinoid tumor of the ascending colon
C7a.023 Malignant carcinoid tumor of the transverse colon
C7a.024 Malignant carcinoid tumor of the descending colon
C7a.025 Malignant carcinoid tumor of the sigmoid colon
C7a.026 Malignant carcinoid tumor of the rectum
C7a. 029 Malignant carcinoid tumor of the large intestine, unspecified portion
Malignant carcinoid tumor of the colon NOS
C7a.09 Malignant carcinoid tumors of other sites
C7a.090 Malignant carcinoid tumor of the bronchus and lung
C7a.091 Malignant carcinoid tumor of the thymus
C7a.092 Malignant carcinoid tumor of the stomach
C7a.093 Malignant carcinoid tumor of the kidney
C7a.094 Malignant carcinoid tumor of the foregut NOS
C7a.095 Malignant carcinoid tumor of the midgut NOS
C7a.096 Malignant carcinoid tumor of the hindgut NOS
C7a.098 Malignant carcinoid tumors of other sites
C7a.1 Malignant poorly differentiated neuroendocrine tumors
Malignant poorly differentiated neuroendocrine tumor NOS
Malignant poorly differentiated neuroendocrine carcinoma, any site
High grade neuroendocrine carcinoma, any site
C7a.8 Other malignant neuroendocrine tumors

Secondary neuroendocrine tumors (C7b)[edit]

C7b Secondary neuroendocrine tumors[edit]

Use additional code to identify any functional activity
C7b.0 Secondary carcinoid tumors
C7b.00 Secondary carcinoid tumors, unspecified site
C7b.01 Secondary carcinoid tumors of distant lymph nodes
Mesentary metastasis of carcinoid tumor
C7b.02 Secondary carcinoid tumors of liver
C7b.03 Secondary carcinoid tumors of bone
C7b.04 Secondary carcinoid tumors of peritoneum
C7b.09 Secondary carcinoid tumors of other sites
C7b.1 Secondary Merkel cell carcinoma
Merkel cell carcinoma nodal presentation
Merkel cell carcinoma visceral metastatic presentation
C7b.8 Other secondary neuroendocrine tumors

Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80)[edit]

C76 Malignant neoplasm of other and ill-defined sites[edit]

Excludes1: malignant neoplasm of female genitourinary tract NOS (C57.9)
malignant neoplasm of male genitourinary tract NOS (C63.9)
malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)
malignant neoplasm of skin (C44.-)
malignant neoplasm of unspecified site NOS (C80.1)
C76.0 Malignant neoplasm of head, face and neck
Malignant neoplasm of cheek NOS
Malignant neoplasm of nose NOS
C76.1 Malignant neoplasm of thorax
Intrathoracic malignant neoplasm NOS
Malignant neoplasm of axilla NOS
Thoracic malignant neoplasm NOS
C76.2 Malignant neoplasm of abdomen
C76.3 Malignant neoplasm of pelvis
Malignant neoplasm of groin NOS
Malignant neoplasm of sites overlapping systems within the pelvis
Rectovaginal (septum) malignant neoplasm
Rectovesical (septum) malignant neoplasm
C76.4 Malignant neoplasm of upper limb
C76.40 Malignant neoplasm of upper limb, unspecified side
C76.41 Malignant neoplasm of right upper limb
C76.42 Malignant neoplasm of left upper limb
C76.5 Malignant neoplasm of lower limb
C76.50 Malignant neoplasm of lower limb, unspecified side
C76.51 Malignant neoplasm of right lower limb
C76.52 Malignant neoplasm of left lower limb
C76.7 Malignant neoplasm of other ill-defined sites

C77 Secondary and unspecified malignant neoplasm of lymph nodes[edit]

Excludes1: malignant neoplasm of lymph nodes, specified as primary (C81-C88, C96.-)
mesentary metastasis of carcinoid tumor (C7b.01)
secondary carcinoid tumors of distant lymph nodes (C7b.01)
C77.0 Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck
Secondary and unspecified malignant neoplasm of supraclavicular lymph nodes
C77.1 Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes
C77.2 Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes
C77.3 Secondary and unspecified malignant neoplasm of axilla and upper limb lymph nodes
Secondary and unspecified malignant neoplasm of pectoral lymph nodes
C77. 4 Secondary and unspecified malignant neoplasm of inguinal and lower limb lymph nodes
C77.5 Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes
C77.8 Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions
C77.9 Secondary and unspecified malignant neoplasm of lymph node, unspecified

C78 Secondary malignant neoplasm of respiratory and digestive organs[edit]

Excludes1: lymph node metastases (C77.0)
secondary carcinoid tumors of liver (C7b.02)
secondary carcinoid tumors of peritoneum (C7b.04)
C78.0 Secondary malignant neoplasm of lung
C78.00 Secondary malignant neoplasm of lung, unspecified side
C78.01 Secondary malignant neoplasm of right lung
C78.02 Secondary malignant neoplasm of left lung
C78.1 Secondary malignant neoplasm of mediastinum
C78.2 Secondary malignant neoplasm of pleura
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
C78.30 Secondary malignant neoplasm of unspecified respiratory organ
C78.39 Secondary malignant neoplasm of other respiratory organs
C78.4 Secondary malignant neoplasm of small intestine
C78.5 Secondary malignant neoplasm of large intestine and rectum
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
C78.7 Secondary malignant neoplasm of liver and intrahepatic bile duct
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
C78.80 Secondary malignant neoplasm of unspecified digestive organ
C78.89 Secondary malignant neoplasm of other digestive organs

C79 Secondary malignant neoplasm of other and unspecified sites[edit]

Excludes1: lymph node metastases (C77.0)
secondary carcinoid tumors (C7b.-)
secondary neuroendocrine tumors (C7b.-)
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
C79. 00 Secondary malignant neoplasm of kidney and renal pelvis, unspecified side
C79.01 Secondary malignant neoplasm of right kidney and renal pelvis
C79.02 Secondary malignant neoplasm of left kidney and renal pelvis
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
C79.10 Secondary malignant neoplasm of unspecified urinary organs
C79.11 Secondary malignant neoplasm of bladder
C79.19 Secondary malignant neoplasm of other urinary organs
C79.2 Secondary malignant neoplasm of skin
Excludes1: secondary Merkel cell carcinoma (C7b.1)
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
C79.31 Secondary malignant neoplasm of brain
C79.32 Secondary malignant neoplasm of cerebral meninges
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
C79.40 Secondary malignant neoplasm of unspecified part of nervous system
C79.49 Secondary malignant neoplasm of other parts of nervous system
C79.5 Secondary malignant neoplasm of bone and bone marrow
Excludes1: secondary carcinoid tumors of bone (C7b.03)
C79.51 Secondary malignant neoplasm of bone
C79.52 Secondary malignant neoplasm of bone marrow
C79.6 Secondary malignant neoplasm of ovary
C79.60 Secondary malignant neoplasm of ovary, unspecified side
C79.61 Secondary malignant neoplasm of right ovary
C79.62 Secondary malignant neoplasm of left ovary
C79.7 Secondary malignant neoplasm of adrenal gland
C79.70 Secondary malignant neoplasm of adrenal gland, unspecified side
C79.71 Secondary malignant neoplasm of right adrenal gland
C79.72 Secondary malignant neoplasm of left adrenal gland
C79.8 Secondary malignant neoplasm of other specified sites
C79.81 Secondary malignant neoplasm of breast
C79.82 Secondary malignant neoplasm of genital organs
C79.89 Secondary malignant neoplasm of other specified sites
C79.9 Secondary malignant neoplasm of unspecified site
Metastatic cancer NOS
Metastatic disease NOS
Excludes1: carcinomatosis NOS (C80.0)
generalized cancer NOS (C80.0)
malignant (primary) neoplasm of unspecified site (C80.1)

C80 Malignant neoplasm without specification of site[edit]

Excludes1: malignant carcinoid tumor of unspecified site (C7a.00)
malignant neoplasm of specified multiple sites- code to each site
C80.0 Disseminated malignant neoplasm, unspecified
Carcinomatosis NOS
Generalized cancer, unspecified site (primary) (secondary)
Generalized malignancy, unspecified site (primary) (secondary)
C80.1 Malignant (primary) neoplasm, unspecified
Cancer NOS
Cancer unspecified site (primary)
Carcinoma unspecified site (primary)
Malignancy unspecified site (primary)
Excludes1: secondary malignant neoplasm of unspecified site (C79.9)
C80.2 Malignant neoplasm associated with transplanted organ
Code first complication of transplanted organ (T86.-)
Use additional code to identify the specific malignancy

Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)[edit]

Excludes2: Kaposi's sarcoma of lymph nodes (C46.3)
secondary and unspecified neoplasm of lymph nodes (C77.-)
secondary neoplasm of bone marrow (C79.52)
secondary neoplasm of spleen (C78.89)

C81 Hodgkin lymphoma[edit]

Excludes1: personal history of Hodgkin lymphoma (Z85.71)
C81.0 Nodular lymphocyte predominant Hodgkin lymphoma
C81.00 Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site
C81.01 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.02 Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes
C81.03 Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes
C81.04 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb
C81.05 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C81. 06 Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes
C81.07 Nodular lymphocyte predominant Hodgkin lymphoma, spleen
C81.08 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites
C81.09 Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites
C81.1 Nodular sclerosis classical Hodgkin lymphoma
C81.10 Nodular sclerosis classical Hodgkin lymphoma, unspecified site
C81.11 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.12 Nodular sclerosis classical Hodgkin lymphoma, intrathoracic lymph nodes
C81.13 Nodular sclerosis classical Hodgkin lymphoma, intra-abdominal lymph nodes
C81.14 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of axilla and upper limb
C81.15 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C81.16 Nodular sclerosis classical Hodgkin lymphoma, intrapelvic lymph nodes
C81.17 Nodular sclerosis classical Hodgkin lymphoma, spleen
C81.18 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of multiple sites
C81.19 Nodular sclerosis classical Hodgkin lymphoma, extranodal and solid organ sites
C81.2 Mixed cellularity classical Hodgkin lymphoma
C81.20 Mixed cellularity classical Hodgkin lymphoma, unspecified site
C81.21 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.22 Mixed cellularity classical Hodgkin lymphoma, intrathoracic lymph nodes
C81.23 Mixed cellularity classical Hodgkin lymphoma, intra-abdominal lymph nodes
C81.24 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of axilla and upper limb
C81.25 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C81.26 Mixed cellularity classical Hodgkin lymphoma, intrapelvic lymph nodes
C81.27 Mixed cellularity classical Hodgkin lymphoma, spleen
C81.28 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of multiple sites
C81. 29 Mixed cellularity classical Hodgkin lymphoma, extranodal and solid organ sites
C81.3 Lymphocytic depletion classical Hodgkin lymphoma
C81.30 Lymphocytic depletion classical Hodgkin lymphoma, unspecified site
C81.31 Lymphocytic depletion classical Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.32 Lymphocytic depletion classical Hodgkin lymphoma, intrathoracic lymph nodes
C81.33 Lymphocytic depletion classical Hodgkin lymphoma, intra-abdominal lymph nodes
C81.34 Lymphocytic depletion classical Hodgkin lymphoma, lymph nodes of axilla and upper limb
C81.35 Lymphocytic depletion classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C81.36 Lymphocytic depletion classical Hodgkin lymphoma, intrapelvic lymph nodes
C81.37 Lymphocytic depletion classical Hodgkin lymphoma, spleen
C81.38 Lymphocytic depletion classical Hodgkin lymphoma, lymph nodes of multiple sites
C81.39 Lymphocytic depletion classical Hodgkin lymphoma, extranodal and solid organ sites
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
Excludes1: nodular lymphocyte predominant Hodgkin lymphoma (C81.0-)
C81.40 Lymphocyte-rich classical Hodgkin lymphoma, unspecified site
C81.41 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.42 Lymphocyte-rich classical Hodgkin lymphoma, intrathoracic lymph nodes
C81.43 Lymphocyte-rich classical Hodgkin lymphoma, intra-abdominal lymph nodes
C81.44 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of axilla and upper limb
C81.45 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C81.46 Lymphocyte-rich classical Hodgkin lymphoma, intrapelvic lymph nodes
C81.47 Lymphocyte-rich classical Hodgkin lymphoma, spleen
C81.48 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of multiple sites
C81.49 Lymphocyte-rich classical Hodgkin lymphoma, extranodal and solid organ sites
C81.7 Other classical Hodgkin lymphoma
Classical Hodgkin lymphoma NOS
C81.70 Other classical Hodgkin lymphoma, unspecified site
C81.71 Other classical Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.72 Other classical Hodgkin lymphoma, intrathoracic lymph nodes
C81.73 Other classical Hodgkin lymphoma, intra-abdominal lymph nodes
C81.74 Other classical Hodgkin lymphoma, lymph nodes of axilla and upper limb
C81.75 Other classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C81.76 Other classical Hodgkin lymphoma, intrapelvic lymph nodes
C81.77 Other classical Hodgkin lymphoma, spleen
C81.78 Other classical Hodgkin lymphoma, lymph nodes of multiple sites
C81.79 Other classical Hodgkin lymphoma, extranodal and solid organ sites
C81.9 Hodgkin lymphoma, unspecified
C81.90 Hodgkin lymphoma, unspecified, unspecified site
C81.91 Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck
C81.92 Hodgkin lymphoma, unspecified, intrathoracic lymph nodes
C81.93 Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes
C81.94 Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb
C81.95 Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb
C81.96 Hodgkin lymphoma, unspecified, intrapelvic lymph nodes
C81.97 Hodgkin lymphoma, unspecified, spleen
C81.98 Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
C81.99 Hodgkin lymphoma, unspecified, extranodal and solid organ sites

C82 Follicular lymphoma[edit]

Includes: follicular lymphoma with or without diffuse areas
Excludes1: personal history of non-Hodgkin lymphoma (Z85.72)
T-cell lymphoma (C84.-)
C82.0 Follicular lymphoma grade I
C82.00 Follicular lymphoma grade I, unspecified site
C82.01 Follicular lymphoma grade I, lymph nodes of head, face, and neck
C82. 02 Follicular lymphoma grade I, intrathoracic lymph nodes
C82.03 Follicular lymphoma grade I, intra-abdominal lymph nodes
C82.04 Follicular lymphoma grade I, lymph nodes of axilla and upper limb
C82.05 Follicular lymphoma grade I, lymph nodes of inguinal region and lower limb
C82.06 Follicular lymphoma grade I, intrapelvic lymph nodes
C82.07 Follicular lymphoma grade I, spleen
C82.08 Follicular lymphoma grade I, lymph nodes of multiple sites
C82.09 Follicular lymphoma grade I, extranodal and solid organ sites
C82.1 Follicular lymphoma grade II
C82.10 Follicular lymphoma grade II, unspecified site
C82.11 Follicular lymphoma grade II, lymph nodes of head, face, and neck
C82.12 Follicular lymphoma grade II, intrathoracic lymph nodes
C82.13 Follicular lymphoma grade II, intra-abdominal lymph nodes
C82.14 Follicular lymphoma grade II, lymph nodes of axilla and upper limb
C82.15 Follicular lymphoma grade II, lymph nodes of inguinal region and lower limb
C82.16 Follicular lymphoma grade II, intrapelvic lymph nodes
C82.17 Follicular lymphoma grade II, spleen
C82.18 Follicular lymphoma grade II, lymph nodes of multiple sites
C82.19 Follicular lymphoma grade II, extranodal and solid organ sites
C82.2 Follicular lymphoma grade III, unspecified
C82.20 Follicular lymphoma grade III, unspecified, unspecified site
C82.21 Follicular lymphoma grade III, unspecified, lymph nodes of head, face, and neck
C82.22 Follicular lymphoma grade III, unspecified, intrathoracic lymph nodes
C82.23 Follicular lymphoma grade III, unspecified, intra-abdominal lymph nodes
C82.24 Follicular lymphoma grade III, unspecified, lymph nodes of axilla and upper limb
C82.25 Follicular lymphoma grade III, unspecified, lymph nodes of inguinal region and lower limb
C82. 26 Follicular lymphoma grade III, unspecified, intrapelvic lymph nodes
C82.27 Follicular lymphoma grade III, unspecified, spleen
C82.28 Follicular lymphoma grade III, unspecified, lymph nodes of multiple sites
C82.29 Follicular lymphoma grade III, unspecified, extranodal and solid organ sites
C82.3 Follicular lymphoma grade IIIa
C82.30 Follicular lymphoma grade IIIa, unspecified site
C82.31 Follicular lymphoma grade IIIa, lymph nodes of head, face, and neck
C82.32 Follicular lymphoma grade IIIa, intrathoracic lymph nodes
C82.33 Follicular lymphoma grade IIIa, intra-abdominal lymph nodes
C82.34 Follicular lymphoma grade IIIa, lymph nodes of axilla and upper limb
C82.35 Follicular lymphoma grade IIIa, lymph nodes of inguinal region and lower limb
C82.36 Follicular lymphoma grade IIIa, intrapelvic lymph nodes
C82.37 Follicular lymphoma grade IIIa, spleen
C82.38 Follicular lymphoma grade IIIa, lymph nodes of multiple sites
C82.39 Follicular lymphoma grade IIIa, extranodal and solid organ sites
C82.4 Follicular lymphoma grade IIIb
C82.40 Follicular lymphoma grade IIIb, unspecified site
C82.41 Follicular lymphoma grade IIIb, lymph nodes of head, face, and neck
C82.42 Follicular lymphoma grade IIIb, intrathoracic lymph nodes
C82.43 Follicular lymphoma grade IIIb, intra-abdominal lymph nodes
C82.44 Follicular lymphoma grade IIIb, lymph nodes of axilla and upper limb
C82.45 Follicular lymphoma grade IIIb, lymph nodes of inguinal region and lower limb
C82.46 Follicular lymphoma grade IIIb, intrapelvic lymph nodes
C82.47 Follicular lymphoma grade IIIb, spleen
C82.48 Follicular lymphoma grade IIIb, lymph nodes of multiple sites
C82.49 Follicular lymphoma grade IIIb, extranodal and solid organ sites
C82.5 Diffuse follicle center lymphoma
C82. 50 Diffuse follicle center lymphoma, unspecified site
C82.51 Diffuse follicle center lymphoma, lymph nodes of head, face, and neck
C82.52 Diffuse follicle center lymphoma, intrathoracic lymph nodes
C82.53 Diffuse follicle center lymphoma, intra-abdominal lymph nodes
C82.54 Diffuse follicle center lymphoma, lymph nodes of axilla and upper limb
C82.55 Diffuse follicle center lymphoma, lymph nodes of inguinal region and lower limb
C82.56 Diffuse follicle center lymphoma, intrapelvic lymph nodes
C82.57 Diffuse follicle center lymphoma, spleen
C82.58 Diffuse follicle center lymphoma, lymph nodes of multiple sites
C82.59 Diffuse follicle center lymphoma, extranodal and solid organ sites
C82.6 Cutaneous follicle center lymphoma
C82.60 Cutaneous follicle center lymphoma, unspecified site
C82.61 Cutaneous follicle center lymphoma, lymph nodes of head, face, and neck
C82.62 Cutaneous follicle center lymphoma, intrathoracic lymph nodes
C82.63 Cutaneous follicle center lymphoma, intra-abdominal lymph nodes
C82.64 Cutaneous follicle center lymphoma, lymph nodes of axilla and upper limb
C82.65 Cutaneous follicle center lymphoma, lymph nodes of inguinal region and lower limb
C82.66 Cutaneous follicle center lymphoma, intrapelvic lymph nodes
C82.67 Cutaneous follicle center lymphoma, spleen
C82.68 Cutaneous follicle center lymphoma, lymph nodes of multiple sites
C82.69 Cutaneous follicle center lymphoma, extranodal and solid organ sites
C82.8 Other types of follicular lymphoma
C82.80 Other types of follicular lymphoma, unspecified site
C82.81 Other types of follicular lymphoma, lymph nodes of head, face, and neck
C82.82 Other types of follicular lymphoma, intrathoracic lymph nodes
C82.83 Other types of follicular lymphoma, intra-abdominal lymph nodes
C82. 84 Other types of follicular lymphoma, lymph nodes of axilla and upper limb
C82.85 Other types of follicular lymphoma, lymph nodes of inguinal region and lower limb
C82.86 Other types of follicular lymphoma, intrapelvic lymph nodes
C82.87 Other types of follicular lymphoma, spleen
C82.88 Other types of follicular lymphoma, lymph nodes of multiple sites
C82.89 Other types of follicular lymphoma, extranodal and solid organ sites
C82.9 Follicular lymphoma, unspecified
C82.90 Follicular lymphoma, unspecified, unspecified site
C82.91 Follicular lymphoma, unspecified, lymph nodes of head, face, and neck
C82.92 Follicular lymphoma, unspecified, intrathoracic lymph nodes
C82.93 Follicular lymphoma, unspecified, intra-abdominal lymph nodes
C82.94 Follicular lymphoma, unspecified, lymph nodes of axilla and upper limb
C82.95 Follicular lymphoma, unspecified, lymph nodes of inguinal region and lower limb
C82.96 Follicular lymphoma, unspecified, intrapelvic lymph nodes
C82.97 Follicular lymphoma, unspecified, spleen
C82.98 Follicular lymphoma, unspecified, lymph nodes of multiple sites
C82.99 Follicular lymphoma, unspecified, extranodal and solid organ sites

C83 Non-follicular lymphoma[edit]

Excludes1: personal history of non-Hodgkin lymphoma (Z85.72)
C83.0 Small cell B-cell lymphoma
Lymphoplasmacytic lymphoma
Nodal marginal zone lymphoma
Non-leukemic variant of B-CLL
Splenic marginal zone lymphoma
Excludes1: chronic lymphocytic leukemia (C91.1)
T-cell lymphoma (C84.0-)
Waldenström's macroglobulinemia (C88.0)
C83.00 Small cell B-cell lymphoma, unspecified site
C83.01 Small cell B-cell lymphoma, lymph nodes of head, face, and neck
C83.02 Small cell B-cell lymphoma, intrathoracic lymph nodes
C83.03 Small cell B-cell lymphoma, intra-abdominal lymph nodes
C83. 04 Small cell B-cell lymphoma, lymph nodes of axilla and upper limb
C83.05 Small cell B-cell lymphoma, lymph nodes of inguinal region and lower limb
C83.06 Small cell B-cell lymphoma, intrapelvic lymph nodes
C83.07 Small cell B-cell lymphoma, spleen
C83.08 Small cell B-cell lymphoma, lymph nodes of multiple sites
C83.09 Small cell B-cell lymphoma, extranodal and solid organ sites
C83.1 Mantle cell lymphoma
Centrocytic lymphoma
Malignant lymphomatous polyposis
C83.10 Mantle cell lymphoma, unspecified site
C83.11 Mantle cell lymphoma, lymph nodes of head, face, and neck
C83.12 Mantle cell lymphoma, intrathoracic lymph nodes
C83.13 Mantle cell lymphoma, intra-abdominal lymph nodes
C83.14 Mantle cell lymphoma, lymph nodes of axilla and upper limb
C83.15 Mantle cell lymphoma, lymph nodes of inguinal region and lower limb
C83.16 Mantle cell lymphoma, intrapelvic lymph nodes
C83.17 Mantle cell lymphoma, spleen
C83.18 Mantle cell lymphoma, lymph nodes of multiple sites
C83.19 Mantle cell lymphoma, extranodal and solid organ sites
C83.3 Diffuse large B-cell lymphoma
Anaplastic diffuse large B-cell lymphoma
CD30-positive diffuse large B-cell lymphoma
Centroblastic diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma, subtype not specified
Immunoblastic diffuse large B-cell lymphoma
Plasmablastic diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma, subtype not specified
T-cell rich diffuse large B-cell lymphoma
Excludes1: mediastinal (thymic) large B-cell lymphoma (C85.2-)
T-cell lymphoma (C84.-)
C83.30 Diffuse large B-cell lymphoma, unspecified site
C83.31 Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck
C83.32 Diffuse large B-cell lymphoma, intrathoracic lymph nodes
C83.33 Diffuse large B-cell lymphoma, intra-abdominal lymph nodes
C83. 34 Diffuse large B-cell lymphoma, lymph nodes of axilla and upper limb
C83.35 Diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb
C83.36 Diffuse large B-cell lymphoma, intrapelvic lymph nodes
C83.37 Diffuse large B-cell lymphoma, spleen
C83.38 Diffuse large B-cell lymphoma, lymph nodes of multiple sites
C83.39 Diffuse large B-cell lymphoma, extranodal and solid organ sites
C83.5 Lymphoblastic (diffuse) lymphoma
B-precursor lymphoma
Lymphoblastic B-cell lymphoma
Lymphoblastic lymphoma NOS
Lymphoblastic T-cell lymphoma
T-precursor lymphoma
C83.50 Lymphoblastic (diffuse) lymphoma, unspecified site
C83.51 Lymphoblastic (diffuse) lymphoma, lymph nodes of head, face, and neck
C83.52 Lymphoblastic (diffuse) lymphoma, intrathoracic lymph nodes
C83.53 Lymphoblastic (diffuse) lymphoma, intra-abdominal lymph nodes
C83.54 Lymphoblastic (diffuse) lymphoma, lymph nodes of axilla and upper limb
C83.55 Lymphoblastic (diffuse) lymphoma, lymph nodes of inguinal region and lower limb
C83.56 Lymphoblastic (diffuse) lymphoma, intrapelvic lymph nodes
C83.57 Lymphoblastic (diffuse) lymphoma, spleen
C83.58 Lymphoblastic (diffuse) lymphoma, lymph nodes of multiple sites
C83.59 Lymphoblastic (diffuse) lymphoma, extranodal and solid organ sites
C83.7 Burkitt lymphoma
Atypical Burkitt lymphoma
Burkitt-like lymphoma
Excludes1 mature B-cell leukemia Burkitt type (C91.a-)
C83.70 Burkitt lymphoma, unspecified site
C83.71 Burkitt lymphoma, lymph nodes of head, face, and neck
C83.72 Burkitt lymphoma, intrathoracic lymph nodes
C83.73 Burkitt lymphoma, intra-abdominal lymph nodes
C83.74 Burkitt lymphoma, lymph nodes of axilla and upper limb
C83. 75 Burkitt lymphoma, lymph nodes of inguinal region and lower limb
C83.76 Burkitt lymphoma, intrapelvic lymph nodes
C83.77 Burkitt lymphoma, spleen
C83.78 Burkitt lymphoma, lymph nodes of multiple sites
C83.79 Burkitt lymphoma, extranodal and solid organ sites
C83.8 Other non-follicular lymphoma
Intravascular large B-cell lymphoma
Lymphoid granulomatosis
Primary effusion B-cell lymphoma
Excludes1: mediastinal (thymic) large B-cell lymphoma (C85.2-)
T-cell rich B-cell lymphoma (C83.3-)
C83.80 Other non-follicular lymphoma, unspecified site
C83.81 Other non-follicular lymphoma, lymph nodes of head, face, and neck
C83.82 Other non-follicular lymphoma, intrathoracic lymph nodes
C83.83 Other non-follicular lymphoma, intra-abdominal lymph nodes
C83.84 Other non-follicular lymphoma, lymph nodes of axilla and upper limb
C83.85 Other non-follicular lymphoma, lymph nodes of inguinal region and lower limb
C83.86 Other non-follicular lymphoma, intrapelvic lymph nodes
C83.87 Other non-follicular lymphoma, spleen
C83.88 Other non-follicular lymphoma, lymph nodes of multiple sites
C83.89 Other non-follicular lymphoma, extranodal and solid organ sites
C83.9 Non-follicular lymphoma, unspecified
C83.90 Non-follicular lymphoma, unspecified, unspecified site
C83.91 Non-follicular lymphoma, unspecified, lymph nodes of head, face, and neck
C83.92 Non-follicular lymphoma, unspecified, intrathoracic lymph nodes
C83.93 Non-follicular lymphoma, unspecified, intra-abdominal lymph nodes
C83.94 Non-follicular lymphoma, unspecified, lymph nodes of axilla and upper limb
C83.95 Non-follicular lymphoma, unspecified, lymph nodes of inguinal region and lower limb
C83.96 Non-follicular lymphoma, unspecified, intrapelvic lymph nodes
C83.97 Non-follicular lymphoma, unspecified, spleen
C83. C83.98 Non-follicular lymphoma, unspecified, lymph nodes of multiple sites

C83.99 Non-follicular lymphoma, unspecified, extranodal and solid organ sites

C84 Mature T/NK-cell lymphomas[edit]

Excludes1: personal history of non-Hodgkin lymphoma (Z85.72)
C84.0 Mycosis fungoides
Excludes1: peripheral T-cell lymphoma, not classified (C84.4-)
C84.00 Mycosis fungoides, unspecified site
C84.01 Mycosis fungoides, lymph nodes of head, face, and neck
C84.02 Mycosis fungoides, intrathoracic lymph nodes
C84.03 Mycosis fungoides, intra-abdominal lymph nodes
C84.04 Mycosis fungoides, lymph nodes of axilla and upper limb
C84.05 Mycosis fungoides, lymph nodes of inguinal region and lower limb
C84.06 Mycosis fungoides, intrapelvic lymph nodes
C84.07 Mycosis fungoides, spleen
C84.08 Mycosis fungoides, lymph nodes of multiple sites
C84.09 Mycosis fungoides, extranodal and solid organ sites
C84.1 Sézary disease
C84.10 Sézary disease, unspecified site
C84.11 Sézary disease, lymph nodes of head, face, and neck
C84.12 Sézary disease, intrathoracic lymph nodes
C84.13 Sézary disease, intra-abdominal lymph nodes
C84.14 Sézary disease, lymph nodes of axilla and upper limb
C84.15 Sézary disease, lymph nodes of inguinal region and lower limb
C84.16 Sézary disease, intrapelvic lymph nodes
C84.17 Sézary disease, spleen
C84.18 Sézary disease, lymph nodes of multiple sites
C84.19 Sézary disease, extranodal and solid organ sites
C84.4 Peripheral T-cell lymphoma, not classified
Lennert's lymphoma
Lymphoepithelioid lymphoma
Mature T-cell lymphoma, not elsewhere classified
C84.40 Peripheral T-cell lymphoma, not classified, unspecified site
C84.41 Peripheral T-cell lymphoma, not classified, lymph nodes of head, face, and neck
C84.42 Peripheral T-cell lymphoma, not classified intrathoracic lymph nodes
C84.43 Peripheral T-cell lymphoma, not classified, intra-abdominal lymph nodes

ICD-10-CM Tabular

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2010 44 Peripheral T-cell lymphoma, not classified, lymph nodes of axilla and upper limb

C84.45 Peripheral T-cell lymphoma, not classified, lymph nodes of inguinal region and lower limb
C84.46 Peripheral T-cell lymphoma, not classified, intrapelvic lymph nodes
C84.47 Peripheral T-cell lymphoma, not classified, spleen
C84.48 Peripheral T-cell lymphoma, not classified, lymph nodes of multiple sites
C84.49 Peripheral T-cell lymphoma, not classified, extranodal and solid organ sites
C84.6 Anaplastic large cell lymphoma, ALK-positive
Anaplastic large cell lymphoma, CD30-positive
C84.60 Anaplastic large cell lymphoma, ALK-positive, unspecified site
C84.61 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of head, face, and neck
C84.62 Anaplastic large cell lymphoma, ALK-positive, intrathoracic lymph nodes
C84.63 Anaplastic large cell lymphoma, ALK-positive, intra-abdominal lymph nodes
C84.64 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of axilla and upper limb
C84.65 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb
C84.66 Anaplastic large cell lymphoma, ALK-positive, intrapelvic lymph nodes
C84.67 Anaplastic large cell lymphoma, ALK-positive, spleen
C84.68 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of multiple sites
C84.69 Anaplastic large cell lymphoma, ALK-positive, extranodal and solid organ sites
C84.7 Anaplastic large cell lymphoma, ALK-negative
Excludes1: primary cutaneous CD30-positive T-cell proliferations (C86.6-)
C84.70 Anaplastic large cell lymphoma, ALK-negative, unspecified site
C84.71 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of head, face, and neck
C84.72 Anaplastic large cell lymphoma, ALK-negative, intrathoracic lymph nodes
C84.73 Anaplastic large cell lymphoma, ALK-negative, intra-abdominal lymph nodes
C84.74 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of axilla and upper limb
C84. 75 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb
C84.76 Anaplastic large cell lymphoma, ALK-negative, intrapelvic lymph nodes
C84.77 Anaplastic large cell lymphoma, ALK-negative, spleen
C84.78 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites
C84.79 Anaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites
C84.a Cutaneous T-cell lymphoma, unspecified
C84.a0 Cutaneous T-cell lymphoma, unspecified, unspecified site
C84.a1 Cutaneous T-cell lymphoma, unspecified lymph nodes of head, face, and neck
C84.a2 Cutaneous T-cell lymphoma, unspecified, intrathoracic lymph nodes
C84.a3 Cutaneous T-cell lymphoma, unspecified, intra-abdominal lymph nodes
C84.a4 Cutaneous T-cell lymphoma, unspecified, lymph nodes of axilla and upper limb
C84.a5 Cutaneous T-cell lymphoma, unspecified, lymph nodes of inguinal region and lower limb
C84.a6 Cutaneous T-cell lymphoma, unspecified, intrapelvic lymph nodes
C84.a7 Cutaneous T-cell lymphoma, unspecified, spleen
C84.a8 Cutaneous T-cell lymphoma, unspecified, lymph nodes of multiple sites
C84.a9 Cutaneous T-cell lymphoma, unspecified, extranodal and solid organ sites
C84.z Other mature T/NK-cell lymphomas
Note: If T-cell lineage or involvement is mentioned in conjunction with a specific lymphoma, code to the more specific description.
Excludes1: angioimmunoblastic T-cell lymphoma (C86.5)
blastic NK-cell lymphoma (C86.4)
enteropathy-type T-cell lymphoma (C86.2)
extranodal NK-cell lymphoma, nasal type (C86.0)
hepatosplenic T-cell lymphoma (C86.1)
primary cutaneous CD30-positive T-cell proliferations (C86.6)
subcutaneous panniculitis-like T-cell lymphoma (C86.3)
T-cell leukemia (C91.1-)
C84.z0 Other mature T/NK-cell lymphomas, unspecified site
C84.z1 Other mature T/NK-cell lymphomas, lymph nodes of head, face, and neck
C84. z2 Other mature T/NK-cell lymphomas, intrathoracic lymph nodes
C84.z3 Other mature T/NK-cell lymphomas, intra-abdominal lymph nodes
C84.z4 Other mature T/NK-cell lymphomas, lymph nodes of axilla and upper limb
C84.z5 Other mature T/NK-cell lymphomas, lymph nodes of inguinal region and lower limb
C84.z6 Other mature T/NK-cell lymphomas, intrapelvic lymph nodes
C84.z7 Other mature T/NK-cell lymphomas, spleen
C84.z8 Other mature T/NK-cell lymphomas, lymph nodes of multiple sites
C84.z9 Other mature T/NK-cell lymphomas, extranodal and solid organ sites
C84.9 Mature T/NK-cell lymphomas, unspecified
NK/T cell lymphoma NOS
Excludes1: mature T-cell lymphoma, not elsewhere classified (C84.4-)
C84.90 Mature T/NK-cell lymphomas, unspecified, unspecified site
C84.91 Mature T/NK-cell lymphomas, unspecified, lymph nodes of head, face, and neck
C84.92 Mature T/NK-cell lymphomas, unspecified, intrathoracic lymph nodes
C84.93 Mature T/NK-cell lymphomas, unspecified, intra-abdominal lymph nodes
C84.94 Mature T/NK-cell lymphomas, unspecified, lymph nodes of axilla and upper limb
C84.95 Mature T/NK-cell lymphomas, unspecified, lymph nodes of inguinal region and lower limb
C84.96 Mature T/NK-cell lymphomas, unspecified, intrapelvic lymph nodes
C84.97 Mature T/NK-cell lymphomas, unspecified, spleen
C84.98 Mature T/NK-cell lymphomas, unspecified, lymph nodes of multiple sites
C84.99 Mature T/NK-cell lymphomas, unspecified, extranodal and solid organ sites

C85 Other and unspecified types of non-Hodgkin lymphoma[edit]

Excludes1: other specified types of T/NK-cell lymphoma (C86.-)
personal history of non-Hodgkin lymphoma (Z85.72)
C85.1 Unspecified B-cell lymphoma
Note: If B-cell lineage or involvement is mentioned in conjunction with a specific lymphoma, code to the more specific description.
C85.10 Unspecified B-cell lymphoma, unspecified site
C85. 11 Unspecified B-cell lymphoma, lymph nodes of head, face, and neck
C85.12 Unspecified B-cell lymphoma, intrathoracic lymph nodes
C85.13 Unspecified B-cell lymphoma, intra-abdominal lymph nodes
C85.14 Unspecified B-cell lymphoma, lymph nodes of axilla and upper limb
C85.15 Unspecified B-cell lymphoma, lymph nodes of inguinal region and lower limb
C85.16 Unspecified B-cell lymphoma, intrapelvic lymph nodes
C85.17 Unspecified B-cell lymphoma, spleen
C85.18 Unspecified B-cell lymphoma, lymph nodes of multiple sites
C85.19 Unspecified B-cell lymphoma, extranodal and solid organ sites
C85.2 Mediastinal (thymic) large B-cell lymphoma
C85.20 Mediastinal (thymic) large B-cell lymphoma, unspecified site
C85.21 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of head, face, and neck
C85.22 Mediastinal (thymic) large B-cell lymphoma, intrathoracic lymph nodes
C85.23 Mediastinal (thymic) large B-cell lymphoma, intra-abdominal lymph nodes
C85.24 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of axilla and upper limb
C85.25 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of inguinal region and lower limb
C85.26 Mediastinal (thymic) large B-cell lymphoma, intrapelvic lymph nodes
C85.27 Mediastinal (thymic) large B-cell lymphoma, spleen
C85.28 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of multiple sites
C85.29 Mediastinal (thymic) large B-cell lymphoma, extranodal and solid organ sites
C85.8 Other specified types of non-Hodgkin lymphoma
C85.80 Other specified types of non-Hodgkin lymphoma, unspecified site
C85.81 Other specified types of non-Hodgkin lymphoma, lymph nodes of head, face, and neck
C85.82 Other specified types of non-Hodgkin lymphoma, intrathoracic lymph nodes
C85.83 Other specified types of non-Hodgkin lymphoma, intra-abdominal lymph nodes
C85. 84 Other specified types of non-Hodgkin lymphoma, lymph nodes of axilla and upper limb
C85.85 Other specified types of non-Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
C85.86 Other specified types of non-Hodgkin lymphoma, intrapelvic lymph nodes
C85.87 Other specified types of non-Hodgkin lymphoma, spleen
C85.88 Other specified types of non-Hodgkin lymphoma, lymph nodes of multiple sites
C85.89 Other specified types of non-Hodgkin lymphoma, extranodal and solid organ sites
C85.9 Non-Hodgkin lymphoma, unspecified
Lymphoma NOS
Malignant lymphoma NOS
Non-Hodgkin lymphoma NOS
C85.90 Non-Hodgkin lymphoma, unspecified, unspecified site
C85.91 Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck
C85.92 Non-Hodgkin lymphoma, unspecified, intrathoracic lymph nodes
C85.93 Non-Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes
C85.94 Non-Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb
C85.95 Non-Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb
C85.96 Non-Hodgkin lymphoma, unspecified, intrapelvic lymph nodes
C85.97 Non-Hodgkin lymphoma, unspecified, spleen
C85.98 Non-Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
C85.99 Non-Hodgkin lymphoma, unspecified, extranodal and solid organ sites

C86 Other specified types of T/NK-cell lymphoma[edit]

Excludes1: anaplastic large cell lymphoma, ALK negative (C84.7-)
anaplastic large cell lymphoma, ALK positive (C84.6-)
mature T/NK-cell lymphomas (C84.-)
other specified types of non-Hodgkin lymphoma (C85.8-)
C86.0 Extranodal NK/T-cell lymphoma, nasal type
C86.1 Hepatosplenic T-cell lymphoma
Alpha-beta and gamma delta types
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
Enteropathy associated T-cell lymphoma
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
C86.4 Blastic NK-cell lymphoma
C86. 5 Angioimmunoblastic T-cell lymphoma
Angioimmunoblastic lymphadenopathy with dysproteinemia {AILD)
C86.6 Primary cutaneous CD30-positive T-cell proliferations
Lymphomatoid papulosis
Primary cutaneous anaplastic large cell lymphoma
Primary cutaneous CD30-positive T-cell lymphoma

C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas[edit]

Excludes1: B-cell lymphoma, unspecified C85.1-
personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
C88.0 Waldenström macroglobulinemia
Lymphoplasmacytic lymphoma with IgM-production
Macroglobulinemia (idiopathic) (primary)
Excludes1: small cell B-cell lymphoma (C83.0)
C88.2 Other heavy chain disease
Franklin's disease
Gamma heavy chain disease
Mu heavy chain disease
C88.3 Immunoproliferative small intestinal disease
Alpha heavy chain disease
Mediterranean lymphoma
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
Lymphoma of skin-associated lymphoid tissue [SALT-lymphoma]
Lymphoma of bronchial-associated lymphoid tissue [BALT-lymphoma]
Excludes1: high malignant (diffuse large B-cell) lymphoma (C83.3-)
C88.8 Other malignant immunoproliferative diseases
C88.9 Malignant immunoproliferative disease, unspecified
Immunoproliferative disease NOS

C90 Multiple myeloma and malignant plasma cell neoplasms[edit]

Excludes1: personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
C90.0 Multiple myeloma
Kahler's disease
Medullary plasmacytoma
Myelomatosis
Plasma cell myeloma
Excludes1: solitary myeloma (C90.3-)
solitary plasmactyoma (C90.3-)
C90.00 Multiple myeloma not having achieved remission
Multiple myeloma with failed remission
Multiple myeloma NOS
C90.01 Multiple myeloma in remission
C90. 02 Multiple myeloma in relapse
C90.1 Plasma cell leukemia
Plasmacytic leukemia
C90.10 Plasma cell leukemia not having achieved remission
Plasma cell leukemia with failed remission
Plasma cell leukemia NOS
C90.11 Plasma cell leukemia in remission
C90.12 Plasma cell leukemia in relapse
C90.2 Extramedullary plasmacytoma
C90.20 Extramedullary plasmacytoma not having achieved remission
Extramedullary plasmacytoma with failed remission
Extramedullary plasmacytoma NOS
C90.21 Extramedullary plasmacytoma in remission
C90.22 Extramedullary plasmacytoma in relapse
C90.3 Solitary plasmacytoma
Localized malignant plasma cell tumor NOS
Plasmacytoma NOS
Solitary myeloma
C90.30 Solitary plasmacytoma not having achieved remission
Solitary plasmacytoma with failed remission
Solitary plasmacytoma NOS
C90.31 Solitary plasmacytoma in remission
C90.32 Solitary plasmacytoma in relapse

C91 Lymphoid leukemia[edit]

Excludes1: personal history of leukemia (Z85.6)
C91.0 Acute lymphoblastic leukemia [ALL]
Note: Code C91.0 should only be used for T-cell and B-cell precursor leukemia
C91.00 Acute lymphoblastic leukemia not having achieved remission
Acute lymphoblastic leukemia with failed remission
Acute lymphoblastic leukemia NOS
C91.01 Acute lymphoblastic leukemia, in remission
C91.02 Acute lymphoblastic leukemia, in relapse
C91.1 Chronic lymphocytic leukemia of B-cell type
Lymphoplasmacyticleukemia
Richter syndrome
Excludes1: lymphoplasmacytic lymphoma (C83.0-)
C91.10 Chronic lymphocytic leukemia of B-cell type not having achieved remission
Chronic lymphocytic leukemia of B-cell type with failed remission
Chronic lymphocytic leukemia of B-cell type NOS
C91.11 Chronic lymphocytic leukemia of B-cell type in remission
C91. 12 Chronic lymphocytic leukemia of B-cell type in relapse
C91.3 Prolymphocytic leukemia of B-cell type
C91.30 Prolymphocytic leukemia of B-cell type not having achieved remission
Prolymphocytic leukemia of B-cell type with failed remission
Prolymphocytic leukemia of B-cell type NOS
C91.31 Prolymphocytic leukemia of B-cell type, in remission
C91.32 Prolymphocytic leukemia of B-cell type, in relapse
C91.4 Hairy-cell leukemia
Leukemic reticuloendotheliosis
C91.40 Hairy cell leukemia not having achieved remission
Hairy cell leukemia with failed remission
Hairy-cell leukemia NOS
C91.41 Hairy-cell leukemia, in remission
C91.42 Hairy cell leukemia, in relapse
C91.5 Adult T-cell lymphoma/leukemia (HTLV-1-associated)
Acute variant of adult T-cell lymphoma/leukemia (HTLV-1-associated)
Chronic variant of adult T-cell lymphoma/leukemia (HTLV-1-associated)
Lymphomatoid variant of adult T-cell lymphoma/leukemia (HTLV-1-associated)
Smouldering variant of adult T-cell lymphoma/leukemia (HTLV-1-associated)
C91.50 Adult T-cell lymphoma/leukemia (HTLV-1-associated) not having achieved remission
Adult T-cell lymphoma/leukemia (HTLV-1-associated) with failed remission
Adult T-cell lymphoma/leukemia (HTLV-1-associated) NOS
C91.51 Adult T-cell lymphoma/leukemia (HTLV-1-associated), in remission
C91.52 Adult T-cell lymphoma/leukemia (HTLV-1-associated), in relapse
C91.6 Prolymophocytic leukemia of T-cell type
C91.60 Prolymophocytic leukemia of T-cell type not having achieved remission
Prolymophocytic leukemia of T-cell type with failed remission
Prolymophocytic leukemia of T-cell type NOS
C91.61 Prolymophocytic leukemia of T-cell type, in remission
C91.62 Prolymophocytic leukemia of T-cell type, in relapse
C91.a Mature B-cell leukemia Burkitt-type
Excludes1: Burkitt lymphoma (C83.7-)
C91. a0 Mature B-cell leukemia Burkitt-type not having achieved remission
Mature B-cell leukemia Burkitt-type with failed remission
Mature B-cell leukemia Burkitt-type NOS
C91.a1 Mature B-cell leukemia Burkitt-type, in remission
C91.a2 Mature B-cell leukemia Burkitt-type, in relapse
C91.z Other lymphoid leukemia
T-cell large granular lymphocytic leukemia
C91.z0 Other lymphoid leukemia not having achieved remission
Other lymphoid leukemia with failed remission
Other lymphoid leukemia NOS
C91.z1 Other lymphoid leukemia, in remission
C91.z2 Other lymphoid leukemia, in relapse
C91.9 Lymphoid leukemia, unspecified
C91.90 Lymphoid leukemia, unspecified not having achieved remission
Lymphoid leukemia with failed remission
Lymphoid leukemia NOS
C91.91 Lymphoid leukemia, unspecified, in remission
C91.92 Lymphoid leukemia, unspecified, in relapse

C92 Myeloid leukemia[edit]

Includes: granulocytic leukemia
myelogenous leukemia
Excludes1: personal history of leukemia (Z85.6)
C92.0 Acute myeloblastic leukemia
Acute myeloblastic leukemia, minimal differentiation
Acute myeloblastic leukemia (with maturation)
Acute myeloblastic leukemia 1/ETO
Acute myeloblastic leukemia M0
Acute myeloblastic leukemia M1
Acute myeloblastic leukemia M2
Acute myeloblastic leukemia with t(8;21)
Acute myeloblastic leukemia (without a FAB classification) NOS
Refractory anemia with excess blasts in transformation [RAEB T]
Excludes1: acute exacerbation of chronic myeloid leukemia (C92.10)
refractory anemia with excess of blasts not in transformation (D46.2-)
C92.00 Acute myeloblastic leukemia, not having achieved remission
Acute myeloblastic leukemia with failed remission
Acute myeloblastic leukemia NOS
C92. 01 Acute myeloblastic leukemia, in remission
C92.02 Acute myeloblastic leukemia, in relapse
C92.1 Chronic myeloid leukemia, BCR/ABL-positive
Chronic myelogenous leukemia, Philadelphia chromosome (Ph1) positive
Chronic myelogenous leukemia, t(9:22) (q34;q11)
Chronic myelogenous leukemia with crisis of blast cells
Excludes1: atypical chronic myeloid leukemia (C92.2-)
chronic myelomonocytic leukemia (C93.1-)
chronic myeloproliferative disease (D47.1)
C92.10 Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission
Chronic myeloid leukemia, BCR/ABL-positive with failed remission
Chronic myeloid leukemia, BCR/ABL-positive NOS
C92.11 Chronic myeloid leukemia, BCR/ABL-positive, in remission
C92.12 Chronic myeloid leukemia, BCR/ABL-positive, in relapse
C92.2 Atypical chronic myeloid leukemia, BCR/ABL-negative
C92.20 Atypical chronic myeloid leukemia, BCR/ABL-negative, not having achieved remission
Atypical chronic myeloid leukemia, BCR/ABL-negative with failed remission
Atypical chronic myeloid leukemia, BCR/ABL-negative NOS
C92.21 Atypical chronic myeloid leukemia, BCR/ABL-negative, in remission
C92.22 Atypical chronic myeloid leukemia, BCR/ABL-negative, in relapse
C92.3 Myeloid sarcoma
A malignant tumor of immature myeloid cells
Chloroma
Granulocytic sarcoma
C92.30 Myeloid sarcoma, not having achieved remission
Myeloid sarcoma with failed remission
Myeloid sarcoma NOS
C92.31 Myeloid sarcoma, in remission
C92.32 Myeloid sarcoma, in relapse
C92.4 Acute promyelocytic leukemia
AML M3
AML Me with t(15;17) and variants
C92.40 Acute promyelocytic leukemia, not having achieved remission
Acute promyelocytic leukemia with failed remission
Acute promyelocytic leukemia NOS
C92. 41 Acute promyelocytic leukemia, in remission
C92.42 Acute promyelocytic leukemia, in relapse
C92.5 Acute myelomonocytic leukemia
AML M4
AML M4 Eo with inv(16) or t(16;16)
C92.50 Acute myelomonocytic leukemia, not having achieved remission
Acute myelomonocytic leukemia with failed remission
Acute myelomonocytic leukemia NOS
C92.51 Acute myelomonocytic leukemia, in remission
C92.52 Acute myelomonocytic leukemia, in relapse
C92.6 Acute myeloid leukemia with 11q23-abnormality
Acute myeloid leukemia with variation of MLL-gene
C92.60 Acute myeloid leukemia with 11q23-abnormality not having achieved remission
Acute myeloid leukemia with 11q23-abnormality with failed remission
Acute myeloid leukemia with 11q23-abnormality NOS
C92.61 Acute myeloid leukemia with 11q23-abnormality in remission
C92.62 Acute myeloid leukemia with 11q23-abnormality in relapse
C92.a Acute myeloid leukemia with multilineage dysplasia
Acute myeloid leukemia with dysplasia of remaining hematopoesis and/or myelodysplastic disease in its history
C92.a0 Acute myeloid leukemia with multilineage dysplasia, not having achieved remission
Acute myeloid leukemia with multilineage dysplasia with failed remission
Acute myeloid leukemia with multilineage dysplasia NOS
C92.a1 Acute myeloid leukemia with multilineage dysplasia, in remission
C92.a2 Acute myeloid leukemia with multilineage dysplasia, in relapse
C92.z Other myeloid leukemia
C92.z0 Other myeloid leukemia not having achieved remission
Myeloid leukemia NEC with failed remission
Myeloid leukemia NEC
C92.z1 Other myeloid leukemia, in remission
C92.z2 Other myeloid leukemia, in relapse
C92.9 Myeloid leukemia, unspecified
C92.90 Myeloid leukemia, unspecified, not having achieved remission
Myeloid leukemia, unspecified with failed remission
Myeloid leukemia, unspecified NOS
C92. 91 Myeloid leukemia, unspecified in remission
C92.92 Myeloid leukemia, unspecified in relapse

C93 Monocytic leukemia[edit]

Includes: monocytoid leukemia
Excludes1: personal history of leukemia (Z85.6)
C93.0 Acute monoblastic/monocytic leukemia
AML M5
AML M5a
AML M5b
C93.00 Acute monoblastic/monocytic leukemia, not having achieved remission
Acute monoblastic/monocytic leukemia with failed remission
Acute monoblastic/monocytic leukemia NOS
C93.01 Acute monoblastic/monocytic leukemia, in remission
C93.02 Acute monoblastic/monocytic leukemia, in relapse
C93.1 Chronic myelomonocytic leukemia
Chronic monocytic leukemia
CMML-1
CMML-2
CMML with eosinophilia
C93.10 Chronic myelomonocytic leukemia not having achieved remission
Chronic myelomonocytic leukemia with failed remission
Chronic myelomonocytic leukemia NOS
C93.11 Chronic myelomonocytic leukemia, in remission
C93.12 Chronic myelomonocytic leukemia, in relapse
C93.3 Juvenile myelomonocytic leukemia
C93.30 Juvenile myelomonocytic leukemia, not having achieved remission
Juvenile myelomonocytic leukemia with failed remission
Juvenile myelomonocytic leukemia NOS
C93.31 Juvenile myelomonocytic leukemia, in remission
C93.32 Juvenile myelomonocytic leukemia, in relapse
C93.z Other monocytic leukemia
C93.z0 Other monocytic leukemia, not in remission
Other monocytic leukemia NOS
C93.z1 Other monocytic leukemia, in remission
C93.9 Monocytic leukemia, unspecified
C93.90 Monocytic leukemia, unspecified, not having achieved remission
Monocytic leukemia, unspecified with failed remission
Monocytic leukemia, unspecified NOS
C93.91 Monocytic leukemia, unspecified in remission
C93. 92 Monocytic leukemia, unspecified in relapse

C94 Other leukemias of specified cell type[edit]

Excludes1: leukemic reticuloendotheliosis (C91.4-)
myelodysplastic syndromes (D46.-)
personal history of leukemia (Z85.6)
plasma cell leukemia (C90.1-)
C94.0 Acute erythoid leukemia
Acute myeloid leukemia M6(a)(b)
Erythroleukemia
C94.00 Acute erythoid leukemia, not having achieved remission
Acute erythoid leukemia with failed remission
Acute erythoid leukemia NOS
C94.01 Acute erythoid leukemia, in remission
C94.02 Acute erythoid leukemia, in relapse
C94.2 Acute megakaryoblastic leukemia
Acute myeloid leukemia M7
Acute megakaryocytic leukemia
C94.20 Acute megakaryoblastic leukemia not having achieved remission
Acute megakaryoblastic leukemia with failied remission
Acute megakaryoblastic leukemia NOS
C94.21 Acute megakaryoblastic leukemia, in remission
C94.22 Acute megakaryoblastic leukemia, in relapse
C94.3 Mast cell leukemia
C94.30 Mast cell leukemia not having achieved remission
Mast cell leukemia with failed remission
Mast cell leukemia NOS
C94.31 Mast cell leukemia, in remission
C94.32 Mast cell leukemia, in relapse
C94.4 Acute panmyelosis with myelofibrosis
Acute myelofibrosis
Excludes1: myelofibrosis NOS (D75.81)
secondary myelofibrosis NOS (D75.81)
C94.40 Acute panmyelosis with myelofibrosis not having achieved remission
Acute myelofibrosis NOS
Acute panmyelosis with myelofibrosis with failed remission
Acute panmyelosis NOS
C94.41 Acute panmyelosis with myelofibrosis, in remission
C94.42 Acute panmyelosis with myelofibrosis, in relapse
C94.6 Myelodysplastic disease, not classified
Myeloproliferative diease, not classified
C94.8 Other specified leukemias
Aggressive NK-cell leukemia
Acute basophilic leukemia
C94.80 Other specified leukemias not having achieved remission
Other specified leukemia with failed remission
Other specified leukemias NOS
C94.81 Other specified leukemias, in remission
C94.82 Other specified leukemias, in relapse

C95 Leukemia of unspecified cell type[edit]

Excludes1: personal history of leukemia (Z85.6)
C95.0 Acute leukemia of unspecified cell type
Acute bilineal leukemia
Acute mixed lineage leukemia
Biphenotypic acute leukemia
Stem cell leukemia of unclear lineage
Excludes1: acute exacerbation of unspecified chronic leukemia (C95.10)
C95.00 Acute leukemia of unspecified cell type not having achieved remission
Acute leukemia of unspecified cell type with failed remission
Acute leukemia NOS
C95.01 Acute leukemia of unspecified cell type, in remission
C95.02 Acute leukemia of unspecified cell type, in relapse
C95.1 Chronic leukemia of unspecified cell type
C95.10 Chronic leukemia of unspecified cell type not having achieved remission
Chronic leukemia of unspecified cell type with failed remission
Chronic leukemia NOS
C95.11 Chronic leukemia of unspecified cell type, in remission
C95.12 Chronic leukemia of unspecified cell type, in relapse
C95.9 Leukemia, unspecified
C95.90 Leukemia, unspecified not having achieved remission
Leukemia, unspecified with failed remission
Leukemia NOS
C95.91 Leukemia, unspecified, in remission
C95.92 Leukemia, unspecified, in relapse

C96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue[edit]

Excludes1: personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
C96.0 Multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis
Histiocytosis X, multisystemic
Letterer-Siwe disease
Excludes1: multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
unifocal Langerhans-cell histiocytosis (C96.6)
C96.2 Malignant mast cell tumor
Aggressive systemic mastocytosis
Mast cell sarcoma
Excludes1: indolent mastocytosis (D47.0)
mast cell leukemia (C94.30)
mastocytosis (congenital) (cutaneous) (Q82.2)
C96.4 Sarcoma of dendritic cells (accessory cells)
Follicular dendritic cell sarcoma
Interdigitating dendritic cell sarcoma
Langerhans cell sarcoma
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
Hand-Schüller-Christian disease
Histiocytosis X, multifocal
Excludes1: multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
unifocal Langerhans-cell histiocytosis (C96.6)
C96.6 Unifocal Langerhans-cell histiocytosis
Eosinophilic granuloma
Histiocytosis X, unifocal
Histiocytosis X NOS
Langerhans-cell histiocytosis NOS
Excludes1: multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
C96.a Histiocytic sarcoma
Malignant histiocytosis
C96.z Other specified malignant neoplasms of lymphoid, hematopoietic and related tissue
C96.9 Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified

In situ neoplasms (D00-D09)[edit]

Includes: Bowen's disease
erythroplasia
grade III intraepithelial neoplasia
Queyrat's erythroplasia
Use additional morphology codes with behavior code /2

D00 Carcinoma in situ of oral cavity, esophagus and stomach[edit]

Excludes1: melanoma in situ (D03.-)
D00.0 Carcinoma in situ of lip, oral cavity and pharynx
Excludes1: carcinoma in situ of aryepiglottic fold or interarytenoid fold, laryngeal aspect (D02.0)
carcinoma in situ of epiglottis:
NOS (D02.0)
suprahyoid portion (D02.0)
carcinoma in situ of skin of lip (D03.0, D04.0)
Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
D00.00 Carcinoma in situ of oral cavity, unspecified site
D00.01 Carcinoma in situ of labial mucosa and vermilion border
D00.02 Carcinoma in situ of buccal mucosa
D00.03 Carcinoma in situ of gingiva and edentulous alveolar ridge
D00.04 Carcinoma in situ of soft palate
D00.05 Carcinoma in situ of hard palate
D00.06 Carcinoma in situ of floor of mouth
D00.07 Carcinoma in situ of tongue
D00.08 Carcinoma in situ of pharynx
Carcinoma in situ of aryepiglottic fold NOS
Carcinoma in situ of hypopharyngeal aspect of aryepiglottic fold
Carcinoma in situ of marginal zone of aryepiglottic fold
D00.1 Carcinoma in situ of esophagus
D00.2 Carcinoma in situ of stomach

D01 Carcinoma in situ of other and unspecified digestive organs[edit]

Excludes1: melanoma in situ (D03.-)
D01.0 Carcinoma in situ of colon
Excludes1: carcinoma in situ of rectosigmoid junction (D01.1)
D01.1 Carcinoma in situ of rectosigmoid junction
D01.2 Carcinoma in situ of rectum
D01.3 Carcinoma in situ of anus and anal canal
Excludes1: carcinoma in situ of anal margin (D04.5)
carcinoma in situ of anal skin (D04.5)
carcinoma in situ of perianal skin (D04.5)
D01.4 Carcinoma in situ of other and unspecified parts of intestine
Excludes1: carcinoma in situ of ampulla of Vater (D01.5)
D01.40 Carcinoma in situ of unspecified part of intestine
D01.49 Carcinoma in situ of other parts of intestine
D01.5 Carcinoma in situ of liver, gallbladder and bile ducts
Carcinoma in situ of ampulla of Vater
D01.7 Carcinoma in situ of other specified digestive organs
Carcinoma in situ of pancreas
D01.9 Carcinoma in situ of digestive organ, unspecified

D02 Carcinoma in situ of middle ear and respiratory system[edit]

Excludes1: melanoma in situ (D03.-)
Use additional code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
D02.0 Carcinoma in situ of larynx
Carcinoma in situ of aryepiglottic fold or interarytenoid fold, laryngeal aspect
Carcinoma in situ of epiglottis (suprahyoid portion)
Excludes1: carcinoma in situ of aryepiglottic fold or interarytenoid fold NOS (D00.08)
carcinoma in situ of hypopharyngeal aspect (D00.08)
carcinoma in situ of marginal zone (D00.08)
D02.1 Carcinoma in situ of trachea
D02.2 Carcinoma in situ of bronchus and lung
D02.20 Carcinoma in situ of bronchus and lung, unspecified side
D02.21 Carcinoma in situ of right bronchus and lung
D02.22 Carcinoma in situ of left bronchus and lung
D02.3 Carcinoma in situ of other parts of respiratory system
Carcinoma in situ of accessory sinuses
Carcinoma in situ of middle ear
Carcinoma in situ of nasal cavities
Excludes1: carcinoma in situ of ear (external) (skin) (D04.2-)
carcinoma in situ of nose NOS (D09.7)
carcinoma in situ of skin of nose (D04.3)
D02.4 Carcinoma in situ of respiratory system, unspecified

D03 Melanoma in situ[edit]

D03.0 Melanoma in situ of lip
D03.1 Melanoma in situ of eyelid, including canthus
D03.10 Melanoma in situ of eyelid, including canthus, unspecified side
D03.11 Melanoma in situ of right eyelid, including canthus
D03.12 Melanoma in situ of left eyelid, including canthus
D03.2 Melanoma in situ of ear and external auricular canal
D03.20 Melanoma in situ of ear and external auricular canal, unspecified side
D03. 21 Melanoma in situ of right ear and external auricular canal
D03.22 Melanoma in situ of left ear and external auricular canal
D03.3 Melanoma in situ of other and unspecified parts of face
D03.30 Melanoma in situ of unspecified part of face
D03.39 Melanoma in situ of other parts of face
D03.4 Melanoma in situ of scalp and neck
D03.5 Melanoma in situ of trunk
D03.51 Melanoma in situ of anal skin
Melanoma in situ of anal margin
Melanoma in situ of perianal skin
D03.52 Melanoma in situ of breast (skin) (soft tissue)
D03.59 Melanoma in situ of other part of trunk
D03.6 Melanoma in situ of upper limb, including shoulder
D03.60 Melanoma in situ of upper limb, including shoulder, unspecified side
D03.61 Melanoma in situ of right upper limb, including shoulder
D03.62 Melanoma in situ of left upper limb, including shoulder
D03.7 Melanoma in situ of lower limb, including hip
D03.70 Melanoma in situ of lower limb, including hip, unspecified side
D03.71 Melanoma in situ of right lower limb, including hip
D03.72 Melanoma in situ of left lower limb, including hip
D03.8 Melanoma in situ of other sites
Melanoma in situ of scrotum
Excludes1: carcinoma in situ of scrotum (D07.61)
D03.9 Melanoma in situ, unspecified

D04 Carcinoma in situ of skin[edit]

Excludes1: erythroplasia of Queyrat (penis) NOS (D07.4)
melanoma in situ (D03.-)
D04.0 Carcinoma in situ of skin of lip
Excludes1: carcinoma in situ of vermilion border of lip (D00.01)
D04.1 Carcinoma in situ of skin of eyelid, including canthus
D04.10 Carcinoma in situ of skin of eyelid, including canthus, unspecified side
D04.11 Carcinoma in situ of skin of right eyelid, including canthus
D04.12 Carcinoma in situ of skin of left eyelid, including canthus
D04.2 Carcinoma in situ of skin of ear and external auricular canal
D04.20 Carcinoma in situ of skin of ear and external auricular canal, unspecified side
D04.21 Carcinoma in situ of skin of right ear and external auricular canal
D04. 22 Carcinoma in situ of skin of left ear and external auricular canal
D04.3 Carcinoma in situ of skin of other and unspecified parts of face
D04.30 Carcinoma in situ of skin of unspecified part of face
D04.39 Carcinoma in situ of skin of other parts of face
D04.4 Carcinoma in situ of skin of scalp and neck
D04.5 Carcinoma in situ of skin of trunk
Carcinoma in situ of anal margin
Carcinoma in situ of anal skin
Carcinoma in situ of perianal skin
Carcinoma in situ of skin of breast
Excludes1: carcinoma in situ of anus NOS (D01.3)
carcinoma in situ of scrotum (D07.61)
carcinoma in situ of skin of genital organs (D07.-)
D04.6 Carcinoma in situ of skin of upper limb, including shoulder
D04.60 Carcinoma in situ of skin of upper limb, including shoulder, unspecified side
D04.61 Carcinoma in situ of skin of right upper limb, including shoulder
D04.62 Carcinoma in situ of skin of left upper limb, including shoulder
D04.7 Carcinoma in situ of skin of lower limb, including hip
D04.70 Carcinoma in situ of skin of lower limb, including hip, unspecified side
D04.71 Carcinoma in situ of skin of right lower limb, including hip
D04.72 Carcinoma in situ of skin of left lower limb, including hip
D04.8 Carcinoma in situ of skin of other sites
D04.9 Carcinoma in situ of skin, unspecified

D05 Carcinoma in situ of breast[edit]

Excludes1: carcinoma in situ of skin of breast (D04.5)
melanoma in situ of breast (skin) (D03.5)
Paget's disease of breast or nipple (C50.-)
D05.0 Lobular carcinoma in situ of breast
D05.01 Lobular carcinoma in situ of right breast
D05.02 Lobular carcinoma in situ of left breast
D05.09 Lobular carcinoma in situ of unspecified breast
D05.1 Intraductal carcinoma in situ of breast
D05.11 Intraductal carcinoma in situ of right breast
D05.12 Intraductal carcinoma in situ of left breast
D05.19 Intraductal carcinoma in situ of unspecified breast
D05.7 Other carcinoma in situ of breast
D05.71 Other carcinoma in situ of right breast
D05.72 Other carcinoma in situ of left breast
D05. 79 Other carcinoma in situ of unspecified breast
D05.9 Unspecified carcinoma in situ of breast
D05.91 Unspecified carcinoma in situ of right breast
D05.92 Unspecified carcinoma in situ of left breast
D05.99 Unspecified carcinoma in situ of unspecified breast

D06 Carcinoma in situ of cervix uteri[edit]

Includes: cervical adenocarcinoma in situ
cervical intraepithelial glandular neoplasia
cervical intraepithelial neoplasia III [CIN III]
severe dysplasia of cervix uteri
Excludes1: cervical intraepithelial neoplasia II [CIN II] (N87.1)
cytologic evidence of malignancy of cervix without histologic confirmation (R87.614)
high grade squamous intraepithelial lesion (HGSIL) of cervix (R87.613)
melanoma in situ of cervix (D03.5)
moderate cervical dysplasia (N87.1)
D06.0 Carcinoma in situ of endocervix
D06.1 Carcinoma in situ of exocervix
D06.7 Carcinoma in situ of other parts of cervix
D06.9 Carcinoma in situ of cervix, unspecified

D07 Carcinoma in situ of other and unspecified genital organs[edit]

Excludes1: melanoma in situ of trunk (D03.5)
D07.0 Carcinoma in situ of endometrium
D07.1 Carcinoma in situ of vulva
Severe dysplasia of vulva
Vulvar intraepithelial neoplasia III [VIN III]
Excludes1: moderate dysplasia of vulva (N90.1)
vulvar intraepithelial neoplasia II [VIN II] (N90.1)
D07.2 Carcinoma in situ of vagina
Severe dysplasia of vagina
Vaginal intraepithelial neoplasia III [VAIN III ]
Excludes1: moderate dysplasia of vagina (N89.1)
vaginal intraepithelial neoplasia II [VIN II] (N89.1)
D07.3 Carcinoma in situ of other and unspecified female genital organs
D07.30 Carcinoma in situ of unspecified female genital organs
D07.39 Carcinoma in situ of other female genital organs
D07.4 Carcinoma in situ of penis
Erythroplasia of Queyrat NOS
D07.5 Carcinoma in situ of prostate
Severe dysplasia of prostate
Excludes1: dysplasia (mild) (moderate) of prostate (N42.3)
prostatic intraepithelial neoplasia III (PIN III) (N42.3)
D07.6 Carcinoma in situ of other and unspecified male genital organs
D07. 60 Carcinoma in situ of unspecified male genital organs
D07.61 Carcinoma in situ of scrotum
D07.69 Carcinoma in situ of other male genital organs

D09 Carcinoma in situ of other and unspecified sites[edit]

Excludes1: melanoma in situ (D03.-)
D09.0 Carcinoma in situ of bladder
D09.1 Carcinoma in situ of other and unspecified urinary organs
D09.10 Carcinoma in situ of unspecified urinary organ
D09.19 Carcinoma in situ of other urinary organs
D09.2 Carcinoma in situ of eye
Excludes1: carcinoma in situ of skin of eyelid (D04.1-)
D09.20 Carcinoma in situ of eye, unspecified side
D09.21 Carcinoma in situ of right eye
D09.22 Carcinoma in situ of left eye
D09.3 Carcinoma in situ of thyroid and other endocrine glands
Excludes1: carcinoma in situ of endocrine pancreas (D01.7)
carcinoma in situ of ovary (D07.39)
carcinoma in situ of testis (D07.69)
D09.7 Carcinoma in situ of other specified sites
D09.9 Carcinoma in situ, unspecified

Benign neoplasms, except benign neuroendocrine tumors (D10-D36)[edit]

Use additional morphology codes with behavior code /0

D10 Benign neoplasm of mouth and pharynx[edit]

D10.0 Benign neoplasm of lip
Benign neoplasm of lip (frenulum) (inner aspect) (mucosa) (vermilion border)
Excludes1: benign neoplasm of skin of lip (D22.0, D23.0)
D10.1 Benign neoplasm of tongue
Benign neoplasm of lingual tonsil
D10.2 Benign neoplasm of floor of mouth
D10.3 Other and unspecified parts of mouth
D10.30 Benign neoplasm of unspecified part of mouth
D10.39 Benign neoplasm of other parts of mouth
Benign neoplasm of minor salivary gland NOS
Excludes1:benign odontogenic neoplasms (D16.4-D16.5)
benign neoplasm of mucosa of lip (D10.0)
benign neoplasm of nasopharyngeal surface of soft palate (D10.6)
D10.4 Benign neoplasm of tonsil
Benign neoplasm of tonsil (faucial) (palatine)
Excludes1: benign neoplasm of lingual tonsil (D10.1)
benign neoplasm of pharyngeal tonsil (D10.6)
benign neoplasm of tonsillar fossa (D10.5)
benign neoplasm of tonsillar pillars (D10.5)
D10.5 Benign neoplasm of other parts of oropharynx
Benign neoplasm of epiglottis, anterior aspect
Benign neoplasm of tonsillar fossa
Benign neoplasm of tonsillar pillars
Benign neoplasm of vallecula
Excludes1: benign neoplasm of epiglottis NOS (D14.1)
benign neoplasm of epiglottis, suprahyoid portion (D14.1)
D10.6 Benign neoplasm of nasopharynx
Benign neoplasm of pharyngeal tonsil
Benign neoplasm of posterior margin of septum and choanae
D10.7 Benign neoplasm of hypopharynx
D10.9 Benign neoplasm of pharynx, unspecified

D11 Benign neoplasm of major salivary glands[edit]

Excludes1: benign neoplasms of specified minor salivary glands which are classified according to their anatomical location
benign neoplasms of minor salivary glands NOS (D10.39)
D11.0 Benign neoplasm of parotid gland
D11.7 Benign neoplasm of other major salivary glands
Benign neoplasm of sublingual salivary gland
Benign neoplasm of submandibular salivary gland
D11.9 Benign neoplasm of major salivary gland, unspecified

D12 Benign neoplasm of colon, rectum, anus and anal canal[edit]

Excludes1: benign carcinoid tumors of the large intestine, and rectum (D3a.02-)
D12.0 Benign neoplasm of cecum
Benign neoplasm of ileocecal valve
D12.1 Benign neoplasm of appendix
Excludes1: benign carcinoid tumor of the appendix (D3a.020)
D12.2 Benign neoplasm of ascending colon
D12.3 Benign neoplasm of transverse colon
Benign neoplasm of hepatic flexure
Benign neoplasm of splenic flexure
D12.4 Benign neoplasm of descending colon
D12.5 Benign neoplasm of sigmoid colon
D12.6 Benign neoplasm of colon, unspecified
Adenomatosis of colon
Benign neoplasm of large intestine NOS
Polyposis (hereditary) of colon
Excludes1: inflammatory polyp of colon (K51.4-)
polyp of colon NOS (K63.5)
D12.7 Benign neoplasm of rectosigmoid junction
D12.8 Benign neoplasm of rectum
Excludes1: benign carcinoid tumor of the rectum (D3a.026)
D12.9 Benign neoplasm of anus and anal canal
Benign neoplasm of anus NOS
Excludes1: benign neoplasm of anal margin (D22.5, D23.5)
benign neoplasm of anal skin (D22.5, D23.5)
benign neoplasm of perianal skin (D22.5, D23.5)

D13 Benign neoplasm of other and ill-defined parts of digestive system[edit]

Excludes1: benign stromal tumors of digestive system (D21.4)
D13.0 Benign neoplasm of esophagus
D13.1 Benign neoplasm of stomach
Excludes1: benign carcinoid tumor of the stomach (D3a.092)
D13.2 Benign neoplasm of duodenum
Excludes1: benign carcinoid tumor of the duodenum (D3a.010)
D13.3 Benign neoplasm of other and unspecified parts of small intestine
Excludes1: benign carcinoid tumors of the small intestine(D3a.01-)
benign neoplasm of ileocecal valve (D12.0)
D13.30 Benign neoplasm of unspecified part of small intestine
D13.39 Benign neoplasm of other parts of small intestine
D13.4 Benign neoplasm of liver
Benign neoplasm of intrahepatic bile ducts
D13.5 Benign neoplasm of extrahepatic bile ducts
D13.6 Benign neoplasm of pancreas
Excludes1: benign neoplasm of endocrine pancreas (D13.7)
D13.7 Benign neoplasm of endocrine pancreas
Islet cell tumor
Benign neoplasm of islets of Langerhans
Use additional code to identify any functional activity.
D13.9 Benign neoplasm of ill-defined sites within the digestive system
Benign neoplasm of digestive system NOS
Benign neoplasm of intestine NOS
Benign neoplasm of spleen

D14 Benign neoplasm of middle ear and respiratory system[edit]

D14.0 Benign neoplasm of middle ear, nasal cavity and accessory sinuses
Benign neoplasm of cartilage of nose
Excludes1: benign neoplasm of auricular canal (external) (D22.2-, D23.2-)
benign neoplasm of bone of ear (D16.4)
benign neoplasm of bone of nose (D16.4)
benign neoplasm of cartilage of ear (D21.0)
benign neoplasm of ear (external)(skin) (D22.2-, D23.2-)
benign neoplasm of nose NOS (D36.7)
benign neoplasm of skin of nose (D22.39, D23.39)
benign neoplasm of olfactory bulb (D33.3)
benign neoplasm of posterior margin of septum and choanae (D10.6)
polyp of accessory sinus (J33.8)
polyp of ear (middle) (H74.4)
polyp of nasal (cavity) (J33.-)
D14.1 Benign neoplasm of larynx
Adenomatous polyp of larynx
Benign neoplasm of epiglottis (suprahyoid portion)
Excludes1: benign neoplasm of epiglottis, anterior aspect (D10.5)
polyp (nonadenomatous) of vocal cord or larynx (J38.1)
D14.2 Benign neoplasm of trachea
D14.3 Benign neoplasm of bronchus and lung
Excludes1: benign carcinoid tumor of the bronchus and lung (D3a.090)
D14.30 Benign neoplasm of bronchus and lung, unspecified side
D14.31 Benign neoplasm of right bronchus and lung
D14.32 Benign neoplasm of left bronchus and lung
D14.4 Benign neoplasm of respiratory system, unspecified

D15 Benign neoplasm of other and unspecified intrathoracic organs[edit]

Excludes1: benign neoplasm of mesothelial tissue (D19.-)
D15.0 Benign neoplasm of thymus
Excludes1: benign carcinoid tumor of the thymus (D3a.091)
D15.1 Benign neoplasm of heart
Excludes1: benign neoplasm of great vessels (D21.3)
D15.2 Benign neoplasm of mediastinum
D15.7 Benign neoplasm of other specified intrathoracic organs
D15.9 Benign neoplasm of intrathoracic organ, unspecified

D16 Benign neoplasm of bone and articular cartilage[edit]

Excludes1: benign neoplasm of connective tissue of ear (D21.0)
benign neoplasm of connective tissue of eyelid (D21.0)
benign neoplasm of connective tissue of larynx (D14.1)
benign neoplasm of connective tissue of nose (D14.0)
benign neoplasm of synovia (D21.-)
D16.0 Benign neoplasm of scapula and long bones of upper limb
D16.00 Benign neoplasm of scapula and long bones of upper limb, unspecified side
D16.01 Benign neoplasm of scapula and long bones of right upper limb
D16.02 Benign neoplasm of scapula and long bones of left upper limb
D16.1 Benign neoplasm of short bones of upper limb
D16. 10 Benign neoplasm of short bones of upper limb, unspecified side
D16.11 Benign neoplasm of short bones of right upper limb
D16.12 Benign neoplasm of short bones of left upper limb
D16.2 Benign neoplasm of long bones of lower limb
D16.20 Benign neoplasm of long bones of lower limb, unspecified side
D16.21 Benign neoplasm of long bones of right lower limb
D16.22 Benign neoplasm of long bones of left lower limb
D16.3 Benign neoplasm of short bones of lower limb
D16.30 Benign neoplasm of short bones of lower limb, unspecified side
D16.31 Benign neoplasm of short bones of right lower limb
D16.32 Benign neoplasm of short bones of left lower limb
D16.4 Benign neoplasm of bones of skull and face
Benign neoplasm of maxilla (superior)
Benign neoplasm of orbital bone
Keratocyst of maxilla
Keratocystic odontogenic tumor of maxilla
Excludes1: benign neoplasm of lower jaw bone (D16.5)
D16.5 Benign neoplasm of lower jaw bone
Keratocyst of mandible
Keratocystic odontogenic tumor of mandible
D16.6 Benign neoplasm of vertebral column
Excludes1: benign neoplasm of sacrum and coccyx (D16.8)
D16.7 Benign neoplasm of ribs, sternum and clavicle
D16.8 Benign neoplasm of pelvic bones, sacrum and coccyx
D16.9 Benign neoplasm of bone and articular cartilage, unspecified

D17 Benign lipomatous neoplasm[edit]

D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limb
D17.20 Benign lipomatous neoplasm of skin and subcutaneous tissue of unspecified limb
D17.21 Benign lipomatous neoplasm of skin and subcutaneous tissue of right arm
D17.22 Benign lipomatous neoplasm of skin and subcutaneous tissue of left arm
D17.23 Benign lipomatous neoplasm of skin and subcutaneous tissue of right leg
D17.24 Benign lipomatous neoplasm of skin and subcutaneous tissue of left leg
D17. 3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
D17.30 Benign lipomatous neoplasm of skin and subcutaneous tissue of unspecified sites
D17.39 Benign lipomatous neoplasm of skin and subcutaneous tissue of other sites
D17.4 Benign lipomatous neoplasm of intrathoracic organs
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
Excludes1: benign lipomatous neoplasm of peritoneum and retroperitoneum (D17.7)
D17.6 Benign lipomatous neoplasm of spermatic cord
D17.7 Benign lipomatous neoplasm of other sites
Benign lipomatous neoplasm of peritoneum
Benign lipomatous neoplasm of retroperitoneum
D17.9 Benign lipomatous neoplasm, unspecified
Lipoma NOS

D18 Hemangioma and lymphangioma, any site[edit]

Excludes1: benign neoplasm of glomus jugulare (D35.6)
blue or pigmented nevus (D22.-)
nevus NOS (D22.-)
vascular nevus (Q82.5)
D18.0 Hemangioma
Angioma NOS
Cavernous nevus
D18.00 Hemangioma unspecified site
D18.01 Hemangioma of skin and subcutaneous tissue
D18.02 Hemangioma of intracranial structures
D18.03 Hemangioma of intra-abdominal structures
D18.09 Hemangioma of other sites
D18.1 Lymphangioma, any site

D19 Benign neoplasm of mesothelial tissue[edit]

D19.0 Benign neoplasm of mesothelial tissue of pleura
D19.1 Benign neoplasm of mesothelial tissue of peritoneum
D19.7 Benign neoplasm of mesothelial tissue of other sites
D19.9 Benign neoplasm of mesothelial tissue, unspecified
Benign mesothelioma NOS

D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum[edit]

Excludes1: benign lipomatous neoplasm of peritoneum and retroperitoneum (D17.7)
benign neoplasm of mesothelial tissue (D19.-)
D20.0 Benign neoplasm of soft tissue of retroperitoneum
D20.1 Benign neoplasm of soft tissue of peritoneum

D21 Other benign neoplasms of connective and other soft tissue[edit]

Includes: benign neoplasm of blood vessel
benign neoplasm of bursa
benign neoplasm of cartilage
benign neoplasm of fascia
benign neoplasm of fat
benign neoplasm of ligament, except uterine
benign neoplasm of lymphatic channel
benign neoplasm of muscle
benign neoplasm of synovia
benign neoplasm of tendon (sheath)
benign stromal tumors
Excludes1: benign neoplasm of articular cartilage (D16.-)
benign neoplasm of cartilage of larynx (D14.1)
benign neoplasm of cartilage of nose (D14.0)
benign neoplasm of connective tissue of breast (D24.-)
benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
benign neoplasm of peritoneum (D20.1)
benign neoplasm of retroperitoneum (D20.0)
benign neoplasm of uterine ligament, any (D28.2)
benign neoplasm of vascular tissue (D18.-)
hemangioma (D18.0-)
lipomatous neoplasm (D17.-)
lymphangioma (D18.1)
uterine leiomyoma (D25.-)
D21.0 Benign neoplasm of connective and other soft tissue of head, face and neck
Benign neoplasm of connective tissue of ear
Benign neoplasm of connective tissue of eyelid
Excludes1: benign neoplasm of connective tissue of orbit (D31.6-)
D21.1 Benign neoplasm of connective and other soft tissue of upper limb, including shoulder
D21.10 Benign neoplasm of connective and other soft tissue of upper limb, including shoulder, unspecified side
D21.11 Benign neoplasm of connective and other soft tissue of right upper limb, including shoulder
D21.12 Benign neoplasm of connective and other soft tissue of left upper limb, including shoulder
D21.2 Benign neoplasm of connective and other soft tissue of lower limb, including hip
D21.20 Benign neoplasm of connective and other soft tissue of lower limb, including hip, unspecified side
D21.21 Benign neoplasm of connective and other soft tissue of right lower limb, including hip
D21. 22 Benign neoplasm of connective and other soft tissue of left lower limb, including hip
D21.3 Benign neoplasm of connective and other soft tissue of thorax
Benign neoplasm of axilla
Benign neoplasm of diaphragm
Benign neoplasm of great vessels
Excludes1: benign neoplasm of heart (D15.1)
benign neoplasm of mediastinum (D15.2)
benign neoplasm of thymus (D15.0)
D21.4 Benign neoplasm of connective and other soft tissue of abdomen
Benign stromal tumors of abdomen
D21.5 Benign neoplasm of connective and other soft tissue of pelvis
Excludes1: benign neoplasm of any uterine ligament (D28.2)
uterine leiomyoma (D25.-)
D21.6 Benign neoplasm of connective and other soft tissue of trunk, unspecified
Benign neoplasm of back NOS
D21.9 Benign neoplasm of connective and other soft tissue, unspecified

D22 Melanocytic nevi[edit]

Includes: atypical nevus
blue hairy pigmented nevus
nevus NOS
D22.0 Melanocytic nevi of lip
D22.1 Melanocytic nevi of eyelid, including canthus
D22.10 Melanocytic nevi of eyelid, including canthus, unspecified side
D22.11 Melanocytic nevi of right eyelid, including canthus
D22.12 Melanocytic nevi of left eyelid, including canthus
D22.2 Melanocytic nevi of ear and external auricular canal
D22.20 Melanocytic nevi of ear and external auricular canal, unspecified side
D22.21 Melanocytic nevi of right ear and external auricular canal
D22.22 Melanocytic nevi of left ear and external auricular canal
D22.3 Melanocytic nevi of other and unspecified parts of face
D22.30 Melanocytic nevi of unspecified part of face
D22.39 Melanocytic nevi of other parts of face
D22.4 Melanocytic nevi of scalp and neck
D22.5 Melanocytic nevi of trunk
Melanocytic nevi of anal margin
Melanocytic nevi of anal skin
Melanocytic nevi of perianal skin
Melanocytic nevi of skin of breast
D22. 6 Melanocytic nevi of upper limb, including shoulder
D22.60 Melanocytic nevi of upper limb, including shoulder, unspecified side
D22.61 Melanocytic nevi of right upper limb, including shoulder
D22.62 Melanocytic nevi of left upper limb, including shoulder
D22.7 Melanocytic nevi of lower limb, including hip
D22.70 Melanocytic nevi of lower limb, including hip, unspecified side
D22.71 Melanocytic nevi of right lower limb, including hip
D22.72 Melanocytic nevi of left lower limb, including hip
D22.9 Melanocytic nevi, unspecified

D23 Other benign neoplasms of skin[edit]

Includes: benign neoplasm of hair follicles
benign neoplasm of sebaceous glands
benign neoplasm of sweat glands
Excludes1: benign lipomatous neoplasms of skin (D17.0-D17.3)
melanocytic nevi (D22.-)
D23.0 Other benign neoplasm of skin of lip
Excludes1: benign neoplasm of vermilion border of lip (D10.0)
D23.1 Other benign neoplasm of skin of eyelid, including canthus
D23.10 Other benign neoplasm of skin of eyelid, including canthus, unspecified side
D23.11 Other benign neoplasm of skin of right eyelid, including canthus
D23.12 Other benign neoplasm of skin of left eyelid, including canthus
D23.2 Other benign neoplasm of skin of ear and external auricular canal
D23.20 Other benign neoplasm of skin of ear and external auricular canal, unspecified side
D23.21 Other benign neoplasm of skin of right ear and external auricular canal
D23.22 Other benign neoplasm of skin of left ear and external auricular canal
D23.3 Other benign neoplasm of skin of other and unspecified parts of face
D23.30 Other benign neoplasm of skin of unspecified part of face
D23.39 Other benign neoplasm of skin of other parts of face
D23.4 Other benign neoplasm of skin of scalp and neck
D23.5 Other benign neoplasm of skin of trunk
Other benign neoplasm of anal margin
Other benign neoplasm of anal skin
Other benign neoplasm of perianal skin
Other benign neoplasm of skin of breast
Excludes1: benign neoplasm of anus NOS (D12.9)
D23.6 Other benign neoplasm of skin of upper limb, including shoulder
D23.60 Other benign neoplasm of skin of upper limb, including shoulder, unspecified side
D23.61 Other benign neoplasm of skin of right upper limb, including shoulder
D23.62 Other benign neoplasm of skin of left upper limb, including shoulder
D23.7 Other benign neoplasm of skin of lower limb, including hip
D23.70 Other benign neoplasm of skin of lower limb, including hip, unspecified side
D23.71 Other benign neoplasm of skin of right lower limb, including hip
D23.72 Other benign neoplasm of skin of left lower limb, including hip
D23.9 Other benign neoplasm of skin, unspecified

D24 Benign neoplasm of breast[edit]

Includes: benign neoplasm of connective tissue of breast
benign neoplasm of soft parts of breast
fibroadenoma of breast
Excludes2: adenofibrosis of breast (N60.2)
benign cyst of breast (N60.-)
benign mammary dysplasia (N60.-)
benign neoplasm of skin of breast (D22.5, D23.5)
fibrocystic disease of breast (N60.-)
D24.0 Benign neoplasm of female breast
D24.00 Benign neoplasm of female breast, unspecified side
D24.01 Benign neoplasm of right female breast
D24.02 Benign neoplasm of left female breast
D24.1 Benign neoplasm of male breast
D24.10 Benign neoplasm of male breast, unspecified side
D24.11 Benign neoplasm of right male breast
D24.12 Benign neoplasm of left male breast

D25 Leiomyoma of uterus[edit]

Includes: uterine fibroid
uterine fibromyoma
uterine myoma
D25.0 Submucous leiomyoma of uterus
D25.1 Intramural leiomyoma of uterus
Interstitial leiomyoma of uterus
D25.2 Subserosal leiomyoma of uterus
Subperitoneal leiomyoma of uterus
D25.9 Leiomyoma of uterus, unspecified

D26 Other benign neoplasms of uterus[edit]

D26.0 Other benign neoplasm of cervix uteri
D26.1 Other benign neoplasm of corpus uteri
D26.7 Other benign neoplasm of other parts of uterus
D26.9 Other benign neoplasm of uterus, unspecified

D27 Benign neoplasm of ovary[edit]

Use additional code to identify any functional activity.
Excludes2: corpus albicans cyst (N83.2)
corpus luteum cyst (N83.1)
endometrial cyst (N80.1)
follicular (atretic) cyst (N83.0)
graafian follicle cyst (N83.0)
ovarian cyst NEC (N83.2)
ovarian retention cyst (N83.2)
D27.0 Benign neoplasm of right ovary
D27.1 Benign neoplasm of left ovary
D27.9 Benign neoplasm of ovary, unspecified side

D28 Benign neoplasm of other and unspecified female genital organs[edit]

Includes: adenomatous polyp
benign neoplasm of skin of female genital organs
benign teratoma
Excludes1: epoophoron cyst (Q50.5)
fimbrial cyst (Q50.4)
Gartner's duct cyst (Q52.4)
parovarian cyst (Q50.5)
D28.0 Benign neoplasm of vulva
D28.1 Benign neoplasm of vagina
D28.2 Benign neoplasm of uterine tubes and ligaments
Benign neoplasm of fallopian tube
Benign neoplasm of uterine ligament (broad) (round)
D28.7 Benign neoplasm of other specified female genital organs
D28.9 Benign neoplasm of female genital organ, unspecified

D29 Benign neoplasm of male genital organs[edit]

Includes: benign neoplasm of skin of male genital organs
D29.0 Benign neoplasm of penis
D29.1 Benign neoplasm of prostate
Excludes1: enlarged prostate (N40.-)
D29.2 Benign neoplasm of testis
Use additional code to identify any functional activity.
D29.20 Benign neoplasm of testis, unspecified side
D29.21 Benign neoplasm of right testis
D29.22 Benign neoplasm of left testis
D29.3 Benign neoplasm of epididymis
D29. 30 Benign neoplasm of epididymis, unspecified side
D29.31 Benign neoplasm of right epididymis
D29.32 Benign neoplasm of left epididymis
D29.4 Benign neoplasm of scrotum
Benign neoplasm of skin of scrotum
D29.7 Benign neoplasm of other male genital organs
Benign neoplasm of seminal vesicle
Benign neoplasm of spermatic cord
Benign neoplasm of tunica vaginalis
D29.9 Benign neoplasm of male genital organ, unspecified

D30 Benign neoplasm of urinary organs[edit]

D30.0 Benign neoplasm of kidney
Excludes1: benign carcinoid tumor of the kidney (D3a.093)
benign neoplasm of renal calyces (D30.1-)
benign neoplasm of renal pelvis (D30.1-)
D30.00 Benign neoplasm of kidney, unspecified side
D30.01 Benign neoplasm of right kidney
D30.02 Benign neoplasm of left kidney
D30.1 Benign neoplasm of renal pelvis
D30.10 Benign neoplasm of renal pelvis, unspecified side
D30.11 Benign neoplasm of right renal pelvis
D30.12 Benign neoplasm of left renal pelvis
D30.2 Benign neoplasm of ureter
Excludes1: benign neoplasm of ureteric orifice of bladder (D30.3)
D30.20 Benign neoplasm of ureter, unspecified side
D30.21 Benign neoplasm of right ureter
D30.22 Benign neoplasm of left ureter
D30.3 Benign neoplasm of bladder
Benign neoplasm of ureteric orifice of bladder
Benign neoplasm of urethral orifice of bladder
D30.4 Benign neoplasm of urethra
Excludes1: benign neoplasm of urethral orifice of bladder (D30.3)
D30.7 Benign neoplasm of other urinary organs
Benign neoplasm of paraurethral glands
D30.9 Benign neoplasm of urinary organ, unspecified
Benign neoplasm of urinary system NOS

D31 Benign neoplasm of eye and adnexa[edit]

Excludes1: benign neoplasm of connective tissue of eyelid (D21.0)
benign neoplasm of optic nerve (D33.3)
benign neoplasm of skin of eyelid (D22.1-, D23.1-)
D31.0 Benign neoplasm of conjunctiva
D31.00 Benign neoplasm of conjunctiva, unspecified side
D31.01 Benign neoplasm of right conjunctiva
D31.02 Benign neoplasm of left conjunctiva
D31.1 Benign neoplasm of cornea
D31. 10 Benign neoplasm of cornea, unspecified side
D31.11 Benign neoplasm of right cornea
D31.12 Benign neoplasm of left cornea
D31.2 Benign neoplasm of retina
Excludes1: dark area on retina (D49.81)
hemangioma of retina (D18.09)
neoplasm of unspecified behavior of retina and choroid (D49.81)
retinal freckle (D49.81)
D31.20 Benign neoplasm of retina, unspecified side
D31.21 Benign neoplasm of right retina
D31.22 Benign neoplasm of left retina
D31.3 Benign neoplasm of choroid
D31.30 Benign neoplasm of choroid, unspecified side
D31.31 Benign neoplasm of right choroid
D31.32 Benign neoplasm of left choroid
D31.4 Benign neoplasm of ciliary body
D31.40 Benign neoplasm of ciliary body, unspecified side
D31.41 Benign neoplasm of right ciliary body
D31.42 Benign neoplasm of left ciliary body
D31.5 Benign neoplasm of lacrimal gland and duct
Benign neoplasm of lacrimal sac
Benign neoplasm of nasolacrimal duct
D31.50 Benign neoplasm of lacrimal gland and duct, unspecified side
D31.51 Benign neoplasm of right lacrimal gland and duct
D31.52 Benign neoplasm of left lacrimal gland and duct
D31.6 Benign neoplasm of orbit, unspecified
Benign neoplasm of connective tissue of orbit
Benign neoplasm of extraocular muscle
Benign neoplasm of peripheral nerves of orbit
Benign neoplasm of retrobulbar tissue
Benign neoplasm of retro-ocular tissue
Excludes1: benign neoplasm of orbital bone (D16.4)
D31.60 Benign neoplasm of orbit, unspecified, unspecified side
D31.61 Benign neoplasm of right orbit, unspecified
D31.62 Benign neoplasm of left orbit, unspecified
D31.9 Benign neoplasm of eye, unspecified
D31.90 Benign neoplasm of eye, unspecified, unspecified side
D31.91 Benign neoplasm of right eye, unspecified
D31.92 Benign neoplasm of left eye, unspecified

D32 Benign neoplasm of meninges[edit]

D32.0 Benign neoplasm of cerebral meninges
D32.1 Benign neoplasm of spinal meninges
D32.9 Benign neoplasm of meninges, unspecified
Meningioma NOS

D33 Benign neoplasm of brain and other parts of central nervous system[edit]

Excludes1: angioma (D18.0-)
benign neoplasm of meninges (D32.-)
benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
hemangioma (D18.0-)
neurofibromatosis (Q85.0)
retro-ocular benign neoplasm (D31.6-)
D33.0 Benign neoplasm of brain, supratentorial
Benign neoplasm of cerebral ventricle
Benign neoplasm of cerebrum
Benign neoplasm of frontal lobe
Benign neoplasm of occipital lobe
Benign neoplasm of parietal lobe
Benign neoplasm of temporal lobe
Excludes1: benign neoplasm of fourth ventricle (D33.1)
D33.1 Benign neoplasm of brain, infratentorial
Benign neoplasm of brain stem
Benign neoplasm of cerebellum
Benign neoplasm of fourth ventricle
D33.2 Benign neoplasm of brain, unspecified
D33.3 Benign neoplasm of cranial nerves
Benign neoplasm of olfactory bulb
D33.4 Benign neoplasm of spinal cord
D33.7 Benign neoplasm of other specified parts of central nervous system
D33.9 Benign neoplasm of central nervous system, unspecified
Benign neoplasm of nervous system (central) NOS

D34 Benign neoplasm of thyroid gland[edit]

Use additional code to identify any functional activity.

D35 Benign neoplasm of other and unspecified endocrine glands[edit]

Use additional code to identify any functional activity.
Excludes1: benign neoplasm of endocrine pancreas (D13.7)
benign neoplasm of ovary (D27.-)
benign neoplasm of testis (D29.2.-)
benign neoplasm of thymus (D15.0)
D35.0 Benign neoplasm of adrenal gland
D35.00 Benign neoplasm of adrenal gland, unspecified side
D35.01 Benign neoplasm of right adrenal gland
D35.02 Benign neoplasm of left adrenal gland
D35.1 Benign neoplasm of parathyroid gland
D35. 2 Benign neoplasm of pituitary gland
D35.3 Benign neoplasm of craniopharyngeal duct
D35.4 Benign neoplasm of pineal gland
D35.5 Benign neoplasm of carotid body
D35.6 Benign neoplasm of aortic body and other paraganglia
Benign tumor of glomus jugulare
D35.7 Benign neoplasm of other specified endocrine glands
D35.8 Benign neoplasm with pluriglandular involvement
D35.9 Benign neoplasm of endocrine gland, unspecified

D36 Benign neoplasm of other and unspecified sites[edit]

D36.0 Benign neoplasm of lymph nodes
Excludes1: lymphangioma (D18.1)
D36.1 Benign neoplasm of peripheral nerves and autonomic nervous system
Excludes1: benign neoplasm of peripheral nerves of orbit (D31.6-)
neurofibromatosis (Q85.0)
D36.10 Benign neoplasm of peripheral nerves and autonomic nervous system, unspecified
D36.11 Benign neoplasm of peripheral nerves and autonomic nervous system of face, head, and neck
D36.12 Benign neoplasm of peripheral nerves and autonomic nervous system, upper limb, including shoulder
D36.13 Benign neoplasm of peripheral nerves and autonomic nervous system of lower limb, including hip
D36.14 Benign neoplasm of peripheral nerves and autonomic nervous system of thorax
D36.15 Benign neoplasm of peripheral nerves and autonomic nervous system of abdomen
D36.16 Benign neoplasm of peripheral nerves and autonomic nervous system of pelvis
D36.17 Benign neoplasm of peripheral nerves and autonomic nervous system of trunk, unspecified
D36.7 Benign neoplasm of other specified sites
Benign neoplasm of nose NOS
D36.9 Benign neoplasm, unspecified site

Benign neuroendocrine tumors (D3a)[edit]

D3a Benign neuroendocrine tumors[edit]

Code also any associated multiple endocrine neoplasia [MEN] syndromes (E31.2-)
Use additional code to identify any associated endocrine syndrome, such as:
carcinoid syndrome (E34.0)
Excludes2: benign pancreatic islet cell tumors (D13.7)
D3a. 0 Benign carcinoid tumors
D3a.00 Benign carcinoid tumor of unspecified site
Carcinoid tumor NOS
D3a.01 Benign carcinoid tumors of the small intestine
D3a.010 Benign carcinoid tumor of the duodenum
D3a.011 Benign carcinoid tumor of the jejunum
D3a.012 Benign carcinoid tumor of the ileum
D3a.019 Benign carcinoid tumor of the small intestine, unspecified portion
D3a.02 Benign carcinoid tumors of the appendix, large intestine, and rectum
D3a.020 Benign carcinoid tumor of the appendix
D3a.021 Benign carcinoid tumor of the cecum
D3a.022 Benign carcinoid tumor of the ascending colon
D3a.023 Benign carcinoid tumor of the transverse colon
D3a.024 Benign carcinoid tumor of the descending colon
D3a.025 Benign carcinoid tumor of the sigmoid colon
D3a.026 Benign carcinoid tumor of the rectum
D3a.029 Benign carcinoid tumor of the large intestine, unspecified portion
Benign carcinoid tumor of the colon NOS
D3a.09 Benign carcinoid tumors of other sites
D3a.090 Benign carcinoid tumor of the bronchus and lung
D3a.091 Benign carcinoid tumor of the thymus
D3a.092 Benign carcinoid tumor of the stomach
D3a.093 Benign carcinoid tumor of the kidney
D3a.094 Benign carcinoid tumor of the foregut NOS
D3a.095 Benign carcinoid tumor of the midgut NOS
D3a.096 Benign carcinoid tumor of the hindgut NOS
D3a.098 Benign carcinoid tumors of other sites
D3a.8 Other benign neuroendocrine tumors
Neuroendocrine tumor NOS

Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)[edit]

Note: Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made. Use additional morphology codes with behavior code /1.
Excludes1: neoplasms of unspecified behavior (D49-)

D37 Neoplasm of uncertain behavior of oral cavity and digestive organs[edit]

Excludes1: stromal tumors of uncertain behavior of digestive system (D48.1)
D37.0 Neoplasm of uncertain behavior of lip, oral cavity and pharynx
Excludes1: neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold, laryngeal aspect (D38.0)
neoplasm of uncertain behavior of epiglottis NOS (D38.0):
neoplasm of uncertain behavior of skin of lip (D48.5)
neoplasm of uncertain behavior of suprahyoid portion of epiglottis (D38.0)
D37.01 Neoplasm of uncertain behavior of lip
Neoplasm of uncertain behavior of vermilion border of lip
D37.02 Neoplasm of uncertain behavior of tongue
D37.03 Neoplasm of uncertain behavior of the major salivary glands
D37.030 Neoplasm of uncertain behavior of the parotid salivary glands
D37.031 Neoplasm of uncertain behavior of the sublingual salivary glands
D37.032 Neoplasm of uncertain behavior of the submandibular salivary glands
D37.039 Neoplasm of uncertain behavior of the major salivary glands, unspecified
D37.04 Neoplasm of uncertain behavior of the minor salivary glands
Neoplasm of uncertain behavior of submucosal salivary glands of lip
Neoplasm of uncertain behavior of submucosal salivary glands of cheek
Neoplasm of uncertain behavior of submucosal salivary glands of hard palate
Neoplasm of uncertain behavior of submucosal salivary glands of soft palate
D37.05 Neoplasm of uncertain behavior of pharynx
Neoplasm of uncertain behavior of aryepiglottic fold of pharynx NOS
Neoplasm of uncertain behavior of hypopharyngeal aspect of aryepiglottic fold of pharynx
Neoplasm of uncertain behavior of marginal zone of aryepiglottic fold of pharynx
D37.09 Neoplasm of uncertain behavior of other specified sites of the oral cavity
D37.1 Neoplasm of uncertain behavior of stomach
D37.2 Neoplasm of uncertain behavior of small intestine
D37.3 Neoplasm of uncertain behavior of appendix
D37. 4 Neoplasm of uncertain behavior of colon
D37.5 Neoplasm of uncertain behavior of rectum
Neoplasm of uncertain behavior of rectosigmoid junction
D37.6 Neoplasm of uncertain behavior of liver, gallbladder and bile ducts
Neoplasm of uncertain behavior of ampulla of Vater
D37.7 Neoplasm of uncertain behavior of other digestive organs
Neoplasm of uncertain behavior of anal canal
Neoplasm of uncertain behavior of anal sphincter
Neoplasm of uncertain behavior of anus NOS
Neoplasm of uncertain behavior of esophagus
Neoplasm of uncertain behavior of intestine NOS
Neoplasm of uncertain behavior of pancreas
Excludes1: neoplasm of uncertain behavior of anal margin (D48.5)
neoplasm of uncertain behavior of anal skin (D48.5)
neoplasm of uncertain behavior of perianal skin (D48.5)
D37.9 Neoplasm of uncertain behavior of digestive organ, unspecified

D38 Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs[edit]

Excludes1: neoplasm of uncertain behavior of heart (D48.7)
D38.0 Neoplasm of uncertain behavior of larynx
Neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold, laryngeal aspect
Neoplasm of uncertain behavior of epiglottis (suprahyoid portion)
Excludes1: neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold NOS (D37.05)
neoplasm of uncertain behavior of hypopharyngeal aspect of aryepiglottic fold (D37.05)
neoplasm of uncertain behavior of marginal zone of aryepiglottic fold (D37.05)
D38.1 Neoplasm of uncertain behavior of trachea, bronchus and lung
D38.2 Neoplasm of uncertain behavior of pleura
D38.3 Neoplasm of uncertain behavior of mediastinum
D38.4 Neoplasm of uncertain behavior of thymus
D38.5 Neoplasm of uncertain behavior of other respiratory organs
Neoplasm of uncertain behavior of accessory sinuses
Neoplasm of uncertain behavior of cartilage of nose
Neoplasm of uncertain behavior of middle ear
Neoplasm of uncertain behavior of nasal cavities
Excludes1: neoplasm of uncertain behavior of ear (external) (skin) (D48.5)
neoplasm of uncertain behavior of nose NOS (D48.7)
neoplasm of uncertain behavior of skin of nose (D48.5)
D38.6 Neoplasm of uncertain behavior of respiratory organ, unspecified

D39 Neoplasm of uncertain behavior of female genital organs[edit]

D39.0 Neoplasm of uncertain behavior of uterus
D39.1 Neoplasm of uncertain behavior of ovary
Use additional code to identify any functional activity.
D39.10 Neoplasm of uncertain behavior of ovary, unspecified side
D39.11 Neoplasm of uncertain behavior of right ovary
D39.12 Neoplasm of uncertain behavior of left ovary
D39.2 Neoplasm of uncertain behavior of placenta
Chorioadenoma destruens
Invasive hydatidiform mole
Malignant hydatidiform mole
Excludes1: hydatidiform mole NOS (O01.9)
D39.7 Neoplasm of uncertain behavior of other female genital organs
Neoplasm of uncertain behavior of skin of female genital organs
D39.9 Neoplasm of uncertain behavior of female genital organ, unspecified

D40 Neoplasm of uncertain behavior of male genital organs[edit]

D40.0 Neoplasm of uncertain behavior of prostate
D40.1 Neoplasm of uncertain behavior of testis
D40.10 Neoplasm of uncertain behavior of testis, unspecified side
D40.11 Neoplasm of uncertain behavior of right testis
D40.12 Neoplasm of uncertain behavior of left testis
D40.7 Neoplasm of uncertain behavior of other male genital organs
Neoplasm of uncertain behavior of skin of male genital organs
D40.9 Neoplasm of uncertain behavior of male genital organ, unspecified

D41 Neoplasm of uncertain behavior of urinary organs[edit]

D41.0 Neoplasm of uncertain behavior of kidney
Excludes1: neoplasm of uncertain behavior of renal pelvis (D41.1-)
D41.00 Neoplasm of uncertain behavior of kidney, unspecified side
D41.01 Neoplasm of uncertain behavior of right kidney
D41.02 Neoplasm of uncertain behavior of left kidney
D41.1 Neoplasm of uncertain behavior of renal pelvis
D41.10 Neoplasm of uncertain behavior of renal pelvis, unspecified side
D41.11 Neoplasm of uncertain behavior of right renal pelvis
D41.12 Neoplasm of uncertain behavior of left renal pelvis
D41.2 Neoplasm of uncertain behavior of ureter
D41.20 Neoplasm of uncertain behavior of ureter, unspecified side
D41.21 Neoplasm of uncertain behavior of right ureter
D41.22 Neoplasm of uncertain behavior of left ureter
D41. 3 Neoplasm of uncertain behavior of urethra
D41.4 Neoplasm of uncertain behavior of bladder
D41.7 Neoplasm of uncertain behavior of other urinary organs
D41.9 Neoplasm of uncertain behavior of urinary organ, unspecified

D42 Neoplasm of uncertain behavior of meninges[edit]

D42.0 Neoplasm of uncertain behavior of cerebral meninges
D42.1 Neoplasm of uncertain behavior of spinal meninges
D42.9 Neoplasm of uncertain behavior of meninges, unspecified

D43 Neoplasm of uncertain behavior of brain and central nervous system[edit]

Excludes1: neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)
D43.0 Neoplasm of uncertain behavior of brain, supratentorial
Neoplasm of uncertain behavior of cerebral ventricle
Neoplasm of uncertain behavior of cerebrum
Neoplasm of uncertain behavior of frontal lobe
Neoplasm of uncertain behavior of occipital lobe
Neoplasm of uncertain behavior of parietal lobe
Neoplasm of uncertain behavior of temporal lobe
Excludes1: neoplasm of uncertain behavior of fourth ventricle (D43.1)
D43.1 Neoplasm of uncertain behavior of brain, infratentorial
Neoplasm of uncertain behavior of brain stem
Neoplasm of uncertain behavior of cerebellum
Neoplasm of uncertain behavior of fourth ventricle
D43.2 Neoplasm of uncertain behavior of brain, unspecified
D43.3 Neoplasm of uncertain behavior of cranial nerves
D43.4 Neoplasm of uncertain behavior of spinal cord
D43.7 Neoplasm of uncertain behavior of other parts of central nervous system
D43.9 Neoplasm of uncertain behavior of central nervous system, unspecified
Neoplasm of uncertain behavior of nervous system (central) NOS

D44 Neoplasm of uncertain behavior of endocrine glands[edit]

Excludes1: neoplasm of uncertain behavior of endocrine pancreas (D37.7)
neoplasm of uncertain behavior of ovary (D39.1-)
neoplasm of uncertain behavior of testis (D40.1-)
neoplasm of uncertain behavior of thymus (D38.4)
D44.0 Neoplasm of uncertain behavior of thyroid gland
D44.1 Neoplasm of uncertain behavior of adrenal gland
Use additional code to identify any functional activity.
D44.10 Neoplasm of uncertain behavior of adrenal gland, unspecified side
D44.11 Neoplasm of uncertain behavior of right adrenal gland
D44.12 Neoplasm of uncertain behavior of left adrenal gland
D44. 2 Neoplasm of uncertain behavior of parathyroid gland
D44.3 Neoplasm of uncertain behavior of pituitary gland
Use additional code to identify any functional activity.
D44.4 Neoplasm of uncertain behavior of craniopharyngeal duct
D44.5 Neoplasm of uncertain behavior of pineal gland
D44.6 Neoplasm of uncertain behavior of carotid body
D44.7 Neoplasm of uncertain behavior of aortic body and other paraganglia
D44.8 Neoplasm of uncertain behavior with pluriglandular involvement
Excludes1: multiple endocrine adenomatosis (E31.2-)
multiple endocrine neoplasia (E31.2-)
D44.9 Neoplasm of uncertain behavior of endocrine gland, unspecified

D45 Polycythemia vera[edit]

Excludes1: familial polycythemia (D75.0)
secondary polycythemia (D75.1)

D46 Myelodysplastic syndromes[edit]

Code first (T36-T50) to identify drug, if drug induced
Excludes2: drug-induced aplastic anemia (D61.1)
D46.0 Refractory anemia without ring sideroblasts, so stated
Refractory anemia without sideroblasts, without excess of blasts
D46.1 Refractory anemia with ring sideroblasts
RARS
D46.2 Refractory anemia with excess of blasts
D46.20 Refractory anemia with excess of blasts, unspecified
RAEB NOS
D46.21 Refractory anemia with excess of blasts 1
RAEB 1
D46.22 Refractory anemia with excess of blasts 2
RAEB 2
D46.a Refractory cytopenia with multilineage dysplasia
D46.b Refractory cytopenia with multilineage dysplasia and ringed sideroblasts
RCMD RS
D46.c Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
Myelodysplastic syndrome with 5q deletion
5q minus syndrome NOS
D46.4 Refractory anemia, unspecified
D46.z Other myelodysplastic syndromes
Excludes1: chronic myelomonocytic leukemia (C93.1-)
D46.9 Myelodysplastic syndrome, unspecified
Myelodysplasia NOS

D47 Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue[edit]

D47.0 Histiocytic and mast cell tumors of uncertain behavior
Indolent systemic mastocytosis
Mast cell tumor NOS
Mastocytoma NOS
Excludes1: malignant mast cell tumor (C96.2)
mastocytosis (congenital) (cutaneous) (Q82.2)
D47.1 Chronic myeloproliferative disease
Chronic neutrophilic leukemia
Myeloproliferative disease, unspecified
Excludes1: atypical chronic myeloid leukemia (C92.2-)
chronic myeloid leukemia BCR/ABL-positive (C92.1-)
myelofibrosis NOS (D75.81)
myelophthisic anemia (D61.82)
myelophthisis (D61.82)
secondary myelofibrosis NOS (D75.81)
D47.2 Monoclonal gammopathy
Monoclonal gammopathy of undetermined significance [MGUS]
D47.3 Essential (hemorrhagic) thrombocythemia
Essential thrombocytosis
Idiopathic hemorrhagic thrombocythemia
D47.4 Osteomyelofibrosis
Chronic idiopathic myelofibrosis
Myelofibrosis (idiopathic) (with myeloid metaplasia)
Myelosclerosis (megakaryocytic) with myeloid metaplasia
Secondary myelofibrosis in myeloproliferative disease
Excludes1: acute myelofibrosis (C94.4-)
D47.z Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
D47.z1 Post-transplant lymphoproliferative disorder (PTLD)
Code first complications of transplanted organs and tissue (T86.-)
D47.z9 Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
Histiocytic tumors of uncertain behavior
D47.9 Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified
Lymphoproliferative disease NOS

D48 Neoplasm of uncertain behavior of other and unspecified sites[edit]

Excludes1: neurofibromatosis (nonmalignant) (Q85.0)
D48. 0 Neoplasm of uncertain behavior of bone and articular cartilage
Excludes1: neoplasm of uncertain behavior of cartilage of ear (D48.1)
neoplasm of uncertain behavior of cartilage of larynx (D38.0)
neoplasm of uncertain behavior of cartilage of nose (D38.5)
neoplasm of uncertain behavior of connective tissue of eyelid (D48.1)
neoplasm of uncertain behavior of synovia (D48.1)
D48.1 Neoplasm of uncertain behavior of connective and other soft tissue
Neoplasm of uncertain behavior of connective tissue of ear
Neoplasm of uncertain behavior of connective tissue of eyelid
Stromal tumors of uncertain behavior of digestive system
Excludes1: neoplasm of uncertain behavior of articular cartilage (D48.0)
neoplasm of uncertain behavior of cartilage of larynx (D38.0)
neoplasm of uncertain behavior of cartilage of nose (D38.5)
neoplasm of uncertain behavior of connective tissue of breast (D48.6-)
D48.2 Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
Excludes1: neoplasm of uncertain behavior of peripheral nerves of orbit (D48.7)
D48.3 Neoplasm of uncertain behavior of retroperitoneum
D48.4 Neoplasm of uncertain behavior of peritoneum
D48.5 Neoplasm of uncertain behavior of skin
Neoplasm of uncertain behavior of anal margin
Neoplasm of uncertain behavior of anal skin
Neoplasm of uncertain behavior of perianal skin
Neoplasm of uncertain behavior of skin of breast
Excludes1: neoplasm of uncertain behavior of anus NOS (D37.7)
neoplasm of uncertain behavior of skin of genital organs (D39.7, D40.7)
neoplasm of uncertain behavior of vermilion border of lip (D37.0)
D48.6 Neoplasm of uncertain behavior of breast
Neoplasm of uncertain behavior of connective tissue of breast
Cystosarcoma phyllodes
Excludes1: neoplasm of uncertain behavior of skin of breast (D48.5)
D48.61 Neoplasm of uncertain behavior of right breast
D48.62 Neoplasm of uncertain behavior of left breast
D48.69 Neoplasm of uncertain behavior of unspecified breast
D48.7 Neoplasm of uncertain behavior of other specified sites
Neoplasm of uncertain behavior of eye
Neoplasm of uncertain behavior of heart
Neoplasm of uncertain behavior of peripheral nerves of orbit
Excludes1: neoplasm of uncertain behavior of connective tissue (D48.1)
neoplasm of uncertain behavior of skin of eyelid (D48.5)
D48. 9 Neoplasm of uncertain behavior, unspecified

D49 Neoplasms of unspecified behavior[edit]

Note: Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term "mass", unless otherwise stated, is not to be regarded as a neoplastic growth.
Includes: "growth" NOS
neoplasm NOS
new growth NOS
tumor NOS
Excludes1: neoplasms of uncertain behavior (D37-D44, D48)
D49.0 Neoplasm of unspecified behavior of digestive system
Excludes1: neoplasm of unspecified behavior of margin of anus (D49.2)
neoplasm of unspecified behavior of perianal skin (D49.2)
neoplasm of unspecified behavior of skin of anus (D49.2)
D49.1 Neoplasm of unspecified behavior of respiratory system
D49.2 Neoplasm of unspecified behavior of bone, soft tissue, and skin
Excludes1: neoplasm of unspecified behavior of anal canal (D49.0)
neoplasm of unspecified behavior of anus NOS (D49.0)
neoplasm of unspecified behavior of bone marrow (D49.9)
neoplasm of unspecified behavior of cartilage of larynx (D49.1)
neoplasm of unspecified behavior of cartilage of nose (D49.1)
neoplasm of unspecified behavior of connective tissue of breast (D49.3)
neoplasm of unspecified behavior of skin of genital organs (D49.5)
neoplasm of unspecified behavior of vermilion border of lip (D49.0)
D49.3 Neoplasm of unspecified behavior of breast
Excludes1: neoplasm of unspecified behavior of skin of breast (D49.2)
D49.4 Neoplasm of unspecified behavior of bladder
D49.5 Neoplasm of unspecified behavior of other genitourinary organs
D49.6 Neoplasm of unspecified behavior of brain
Excludes1: neoplasm of unspecified behavior of cerebral meninges (D49.7)
neoplasm of unspecified behavior of cranial nerves (D49.7)
D49.7 Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
Excludes1: neoplasm of unspecified behavior of peripheral, sympathetic, and parasympathetic nerves and ganglia (D49.2)
D49.8 Neoplasm of unspecified behavior of other specified sites
Excludes1: neoplasm of unspecified behavior of eyelid (skin) (D49.2)
neoplasm of unspecified behavior of eyelid cartilage (D49.2)
neoplasm of unspecified behavior of great vessels (D49.2)
neoplasm of unspecified behavior of optic nerve (D49.7)
D49.81 Neoplasm of unspecified behavior of retina and choroid
Dark area on retina
Retinal freckle
D49.89 Neoplasm of unspecified behavior of other specified sites
D49.9 Neoplasm of unspecified behavior of unspecifiedsite