of fatigue result largely from events happening outside of the brain and spinal cord, events of which 1 have been speaking under the head of physical and chemical phenomena. Such events are not, however, confined to the particular tissues that have performed the fatiguing work, for fatigue substances, though produced in one tissue and fatiguing it, may be carried by the blood to others and there also exert their characteristic action. This fact, that the excessive work of one tissue may cause the fatigue of other tissues, is of great practical importance to us in our daily life. We all believe that excessive muscular work may cause mental weariness. It has been shown by laboratory experimentation that the reverse is true, that excessive mental work may cause muscular weariness. In an experiment upon himself Dr. Maggiora, of Turin, found that the flexor muscles of his middle finger, upon being stimulated by an electric current applied directly to them, were capable of lifting a certain weight fifty-three times before temporary exhaustion set in (Fig. 6). Soon after the completion of the test he entered the class room and devoted the subsequent three and one half hours to the oral examination of students, a task which, he being then a teacher of little experience, was excessively difficult. Immediately after the end of the examination he tested his lifting power again and found his muscles capable of making only twelve contractions. It is often thought that the best means of recuperating after a day's hard mental labor is through the performance of physical exercise. A temporary change of occupation may, indeed, be of great benefit, by relieving an exhausted organ and an exhausted focus of attention. But physiology tells us that a tired brain means a tired body, and that with the brain fagged there is nothing culpable in a desire for not only mental but physical rest.
But there is another aspect of personal fatigue which we can not neglect. Our sensations become our servants or our masters, according as we will. Either we control them, or they control us. Is it legitimate, is it moral, to yield to every sign of weariness? Here we meet at once the problem of the formation of habits. Fatigue may easily become with us a habit, a habit which is destructive to legitimate effort. We have all known the perpetually tired man, the chronically fatigued, to whom both initiative and performance alike are distasteful and to be avoided, when possible. This condition may at times be so pronounced as to be positively pathological, demanding special curative treatment. Fortunately such a condition is rare. Most of us may live on a high or a low plane of activity at will; we may do much or little; we may yield early to fatigue or we may successfully resist it for a time with impunity.
The more one studies physiology the more one appreciates the fact that protoplasm possesses an enormous power of work, and that the human body is endowed with marvelous capacity. Whether we shall
