File:Hemoglobinopathies-Slicing-the-Gordian-Knot-of-Plasmodium-falciparum-Malaria-Pathogenesis-ppat.1003327.g001.jpg
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Summary
| Description |
English: (A) Restriction of red blood cell (RBC) invasion or intraerythrocytic growth, thereby suppressing parasite densities in vivo; (B) interference with parasite-derived mediators of pathogenesis, including those involved in the binding of parasite-infected RBCs (iRBCs) to extracellular host receptors; (C) modulation of innate host defenses to favor protective, anti-inflammatory responses over those that drive pathogenic, pro-inflammatory responses; (D) enhancement of adaptive cell-mediated and humoral immune responses that clear iRBCs from the blood. |
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| Date | ||||
| Source | Image file from Taylor S, Cerami C, Fairhurst R (2013). "Hemoglobinopathies: Slicing the Gordian Knot of Plasmodium falciparum Malaria Pathogenesis". PLOS Pathogens. DOI:10.1371/journal.ppat.1003327. PMID 23696730. PMC: 3656091. | |||
| Author | Taylor S, Cerami C, Fairhurst R | |||
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 23:08, 20 October 2014 | | 759 × 686 (170 KB) | Recitation-bot | Automatic upload of media from: doi:10.1371/journal.ppat.1003327 |
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