| Study year | Report number[1] | Laboratory | Test material | Response rate[2] | Irritancy | Classification as irritant (Y/N)[3][4] | Current use of material | |
|---|---|---|---|---|---|---|---|---|
| Score[5] | No. of subjects with score | |||||||
| 77–512–70 (continued) | F. Purple granules | 1/71 | 5 | 1 | Y[6] | |||
| G. No sample | — | — | — | — | ||||
| H. Brown liquid | 0/71[7] | NR | — | N | ||||
| I. Amber liquid | 1/71 | 1 | 1 | N | ||||
| J. Paper, CB surface with ruptured capsules | 1/71 | 2 | 1 | N | ||||
| K. Paper, CB surface with intact capsules | 0/71 | NR | — | N | ||||
| 1977 | 77–513–70 | Hill Top Research, Inc. | A. Code 29 CFB, sheets of paper (CF surface colored from ruptured capsules of CB surface) | 0/12 | NR | — | N | Test materials discontinued in late 1970s |
| B. Code 29 CFB, sheets of paper (uncolored CF surface) | 0/12 | NR | — | N | ||||
| C. 24W CB (E73–8) plus, blue liquid | 0/12 | NR | — | N | ||||
| D. Code 23 oil plus, blue liquid | 1/12 | 1 | 1 | N | ||||
| E. Code 24 CB (E73–8) dried, white powder | 0/12 | NR | — | N | ||||
| F. Code 24 CB (E73–8) plus, light blue powder | 1/12 | 1 | 1 | N | ||||
| G. No G sample | N/A | NR | — | N | ||||
| H. Code 28 oil, blue liquid | 0/12 | NR | — | N | ||||
________________
See footnotes at end of table.
Adapted from Graves and Tardiff [1999] supplemental submission of peer review comments.
- ↑ The report numbers refer to submissions to the NIOSH docket; they are not listed in the references. Except in Report 86–5436H, no test results for control materials are included in this table.
- ↑ Number of responders/total number of persons who completed the study.
- ↑ Abbreviations: CB=coated back; CF=coated front; CFB=coated front and back; N=no; NA=not applicable; ND=no data provided; NR=no reaction; Y=yes.
- ↑ Y and N were determined by NIOSH according to the scoring system listed in footnote 3.
- ↑ Highest recorded grade of skin reaction per study participant for a particular test material (based on multiple applications). Before 1980, Hill Top Research, Inc. employed a scoring scale that ranged from 0 to 7 (a score of 5 or greater=primary skin irritant; less than 5=nonirritating). Since 1980, Hill Top has used a scoring scale that ranges from 0 to 5 (a score of 3 or greater=primary skin irritant; less than 3=nonirritating). Inveresk Research International used a scoring system of 0 to 8, with a score of 5 or greater indicating irritancy. This laboratory scoring system is more analogous to the Hill Top pre-1980 system, even though it is a post-1980 study.
- ↑ The study director described skin reactions as sensitization.
- ↑ A responder to sample H (grade 1 reaction) was dropped (77–512–70 H).
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