TEE ZOOLOOT OF TO-DAY 255
But MendeFfl achievement was to discover order where no order had been recognized^ to demonstrate that the combinations which are made are of a constant character and^ moreover^ are embodied in groups of grandchildren numerically proportionate to one another. We have seen thad; where^ as in the case of the guinea pigs^ two pairs of characters are considered, there will be four kinds of grandchildren. It may be added that in such a case the four kinds will be represented by the proportional numbers 3, 3, 9, 1. That is, for three of one kind, there will be three of another, nine of another and one of yet another. The larger the number of contrasting points, the greater will be the number of kinds of grandchildren. Thus Correns, one of the rediscov- erers of the Mendelian principles, calculates that if the first parents differ in respect to ten points there will be more than a thousand dif- ferent kinds of grandchildren.
Mendel's explanation of the phenomena that now bear his name was in the shape of an hypothesis which with various alterations, some of which are important, is in general use to-day. He conceived of each contrasting character as potentially represented in a germ cell by a par- ticular '^ something.^' This something we speak of as a germinal factor, a unit-factor or a gene. It is thought of as a definite entity. Many, indeed, perhaps most, look on it as a material particle. Others do not make the attempt to visualize it. When the egg and sperm fuse, cor- responding germinal factors are brought together in pairs, each pair of factors representing a pair of contrasting characters, blackness and whiteness of rabbit fur, for example. Thus brought together in the fertilized egg, the two factors of a pair may each produce an effect on the body of the organism into which the egg develops. Or one factor may completely dominate the other, the organism bearing the impress of ihat factor alone, the other lying dormant. When, for example, in the egg of the rabbit, the factors for blackness and whiteness are brought together, the factor for blackness being dominant, the egg de- velops into a black rabbit. But now as the germ cells are formed which will give rise to the next generation, the factors are supposed to be sorted out among them in such wise that any one germ cell does not get both, but only one, of a pair of factors. Thus, in our example, eggs will be produced having the factor for blackness only, and others the factor for whiteness only. Similarly with the sperm cells, some will have the factor for blackness, some that for whiteness. "So germ cell will have both factors. This separation of the factors with the result that the germ cells produced in an individual are unlike, is the most important feature of the Mendelian hypothesis. Working on this hypothesis, it can be calculated what will be the proportionate number of individuals embodying any particular combination of characters which, through experiment, have been found to behave in Mendelian fashion. The hypothesis has received wide and striking confirmation in that the
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