Page:Chronicles of pharmacy (Volume 2).djvu/66

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Mel Ægyptiacum

is a very ancient compound used chiefly by veterinarians as an escharotic. Its name suggests Egyptian origin, but it has not been traced further back than to the "Grabadin" of John Mesué, the Arabian author, about the year 800. Scribonius Largus before him gives a similar formula under the name of Hygra. Mesué's formula was to boil 1 oz. of vinegar with 1 oz. of honey to the consistence of honey and to add 2 drachms of verdigris. This formula was modified in various ways in the different pharmacopœias in which it was adopted; alum was added in some cases, cream of tartar in others. The chemical action varied with the process, but generally the result was to reduce a part of the verdigris to an oxide of copper, metallic copper, and a little basic acetate in different proportions. The compound appeared in the London Pharmacopœia of 1721 as Unguentum Ægyptiacum; in that of 1746 as Mel Ægyptiacum; as Oxymel Æruginis in that of 1788; and as Linimentum Æruginis in the P.L. 1851. In this last edition the formula given was to dissolve 1 oz. of verdigris in 7 oz. of vinegar, and boil this with 14 oz. of honey to a proper consistence. It was not adopted in the British Pharmacopœia. In old veterinary recipes it was often combined with tincture of myrrh to form a detergent liniment, and occasionally in a very diluted form was administered internally as a tonic. On the Continent, where its employment lingered longer than in this country, an Egyptiac of Solleysel, from which the vinegar was omitted, but litharge, sulphate of zinc, and arsenic in small proportions added, was frequently preferred to the original.

An Unguentum Ægyptiacum magis compositum, con-