offer the same degree of resistance to intestinal and other poisons, and the great eliminating organs begin to exhibit a gradual lessening in functional activity. The theories of immunity rest upon the assumption of the presence of some proteid body in the blood which endows the whole system with powers of resistance to toxins. Exhaustion, especially such as is induced by the emotions, fatigue, grief, anger and fear, are well known to weaken the protective power of these mysterious agencies. At the time of the so-called change of life, woman is usually burdened with the maximum of her cares and labors and too often at this time the severest griefs assail. If she be single there is a species of spiritual awakening and the realization that youth is utterly past. In married women the disappointments which follow upon enthusiastic expectations become manifest, and in numberless ways strains are thrust upon the organism. It must be remembered that the greatest maturity of the powers, also, are evident at this time, and therefore she should be capable of meeting all exigencies. The whole question may be summed up in a few words: if a woman, married or single, will so order her life that she retains to the best of her ability her physical and mental vigor, and if she also sets her face sedulously toward looking upon the bright side of existence and ignores emotional impressions of a disagreeable character, she has nothing to fear as life moves steadily on the downward incline
