recent demonstration of biologic varieties among the rusts, mildews and fusariums opens a large and important field of research. The agencies operating as disease distributors, the wind, insects, soil, man, water or what not must be known that such distribution be more readily controlled. The causes of resistance and susceptibility to certain diseases rest in obscurity, except in a few cases where the responsibility has been fixed upon some particular structure or chemical. The breeding of plants resistant to specific diseases not readily amenable to other means of control must proceed. Such work is now in progress with cotton, melons, tomatoes, tobacco, grains, flax and other plants. The relation existing between many root fungi and bacteria and the roots they inhabit remains to be studied. Aside from parasitism there is also mutualism, a kind of beneficial disease falling to the province of plant pathology. It needs much further study.
Specific problems also abound, the peach yellows and rosette, the mycoplasm theory of rusts, the grape Brunnisure. Differences of opinion now exist or the technique or scientific data are insufficient for an adequate solution of these questions and many other similar ones. Work on timber protection, while not strictly a question of disease, but rather a post-mortem problem, falls to the lot of the pathologist for the want of a more appropriate place. That intensive study of a disease, however thoroughly it may seem to have been studied before, may lead to important development is well illustrated in the case of the familiar pear blight, which, though known for ages and the topic of masterly classic research, has recently, under trained observation and critical interpretation and experimentation, revealed new secrets leading to more masterful and complete control. The large fields of plant pathology, grouped under the term 'physiological disorders' are still practically unworked; diseases due to false nutrition, absorption or assimilation, or to impaired carbon assimilation owing to improper environment, to crowding or shading or to hereditary inabilities. A start has been made sufficient to show the importance of the results awaiting.
The recent discovery of the so-called ultramicroscopic organisms or filterable enzymes which has robbed the bacteria of the distinction of being the smallest of living things opens a new field in both plant and animal pathology comparable in kind, though probably not in magnitude, with the creation of bacteriology by Pasteur. It is yet unknown whether we have to do here with organisms or enzymes, and contemplation of the problems awaiting in this realm places us in a position to appreciate more fully than ever before the great controversy of spontaneous generation as fought in the sixties. The announcement in a recent periodical of the discovery of soluble protoplasm emphasizes the existence of a vast unknown covered by the words protoplasm,
