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THE SIGN OF FOUR.

roused and excited, but it is a pathological and morbid process, which involves increased tissue-change and may at last leave a permanent weakness. You know, too, what a black reaction comes upon you. Surely the game is hardly worth the candle. Why should you, for a mere passing pleasure, risk the loss of those great powers with which you have been endowed? Remember that I speak not only as one comrade to another, but as a medical man to one for whose constitution he is to some extent answerable.'

He did not seem offended. On the contrary, he put his finger-tips together, and leaned his elbows on the arms of his chair, like one who has a relish for conversation.

'My mind,' he said, 'rebels at stagnation. Give me problems, give me work, give me the most abstruse cryptogram, or the most intricate analysis, and I am in my own proper atmosphere. I can dispense then with