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induced according to the degree of energy of its operation. I incline still to believe that this was a correct interpretation of the phenomena of active congestion.
Inflammatory congestion also may be brought about by nervous agency. This fact being of fundamental importance, and not perhaps universally recognised by pathologists, I may describe briefly two unpublished experiments with regard to it which I did shortly after the time of which I have been speaking. Inflammatory phenomena being of a very languid character in the frog, I had resort to a higher animal. One of the experiments was simply passing a silk thread through a fold of skin in a rabbit's back and knotting the ends together. When 48 hours had elapsed, the animal having been killed, I removed the portion of skin concerned and examined its under surface. The thread was covered with a yellow line of lymph, around which there was intense scarlet redness for about a quarter of an inch in every direction, contrasting strongly with the paleness of the healthy structures around. And on microscopic examination I found that this depended (to quote from my notes of the time) "partly upon ecchymoses, but chiefly upon well-marked inflammatory congestion of the minutest vessels of the subcutaneous tissue and the deeper parts of the skin."
The other experiment was performed twenty minutes before the first, upon a part of the same animal which, being more sensitive, was more likely to show the effects of nervous disturbance. By means of
