- factory evidence was obtained from a sixth part of the stomach, and
also from the same proportion of the liver.
Process of Marsh.—The chief difficulties in applying the process of Marsh to complex organic mixtures arise from the tendency of oxide of arsenic to adhere with obstinacy to some organic principles in the solid state, and from the liability of the gas disengaged in the apparatus to raise organic fluids in a fine froth, which breaks up slowly, and is therefore apt to pass over into the exit-tube. Many contrivances have been devised, to meet these difficulties, especially by the French chemists and toxicologists, whose attention was turned earnestly to the subject by the investigations carried on in certain late criminal trials of great interest and importance. The various devices now alluded to were subjected to trial in 1841 by a Committee of the French Institute; who came to the opinion that the following method suggested by MM. Flandin and Danger is the most convenient and comprehensive.[1]
Heat the organic matter with a sixth of its weight of strong sulphuric acid; when complete solution has taken place, concentrate the fluid to a friable almost dry charcoal; add a little concentrated nitric acid gradually to this when cold, and again evaporate to dryness; then act on the residue with boiling distilled water, and a solution of a reddish-brown colour is obtained, which may be used in such an apparatus as that of Döbereiner without risk of obstruction from froth.—The arseniuretted-hydrogen, thus disengaged along with the hydrogen gas, is to be submitted to the succession of tests described in speaking of Marsh's process for detecting arsenic in a state of simple solution [p. 212].
This method of investigation is exceedingly precise and conclusive. The sulphuric acid aided by heat destroys organic matter sufficiently to prevent frothing in the apparatus and dissolves out arsenic from a state of combination with organic principles; and nitric acid afterwards converts any arsenic in the half-charred mass into the soluble arsenic acid. It has been employed with success in various medico-legal proceedings in France. It answers well for detecting oxide of arsenic in the viscera, muscles, and other parts of the body into which the poison has been conveyed through absorption.
Process by Hydrosulphuric Acid.—This method may be employed in two ways, according as the object is merely to prove the presence of oxide of arsenic, or to ascertain also its quantity.
a. If proof of its presence be all that is wanted, cut any soft solids into small pieces, add distilled water if necessary, boil for half an hour, let the decoction cool, and filter it. Add a little acetic acid to the filtered fluid, and if any precipitate form, filter again. Evaporate to dryness, first by ebullition, afterwards over the vapour-bath. Dissolve the residuum again in repeated portions of boiling distilled water, and filter the solution. If it be not acid to litmus-paper add more acetic acid, and transmit hydrosulphuric acid gas through the fluid until an excess be indicated by the sense of smell after agitation,
- ↑ Journal de Chimie Médicale, 1841, p. 413.
