Page:Treatise on poisons in relation to medical jurisprudence, physiology, and the practice of physic (IA treatiseonpoison00chriuoft).pdf/336

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one for the medical jurist to determine precisely; for running quicksilver has been given with a criminal intent. A case of the kind forms the subject of a medico-legal report in Pyl's Repertory;[1] and another is mentioned in Klein's Annals.[2]

It is well ascertained that large quantities of fluid mercury have been repeatedly swallowed, without any injury or peculiar effect having followed. In neither of the German cases now referred to was any bad effect produced; and it has proved equally harmless when given medicinally to remove obstruction in the intestines. Farther, M. Gaspard mentions in his paper quoted in a former page, that he has left large quantities shut up for many hours in the various cavities of the body in animals, without observing any other result than at times inflammation, which was evidently owing to the mere presence of a foreign body, and not to the action of an irritant poison.[3]

It has been already stated, however, that the vapours of metallic mercury, even at the temperature of the air, produce mercurialism when inhaled. But then, in all likelihood, some of the metal is oxidated before being inhaled. At least the chemist knows that the surface of a mercurial trough soon tarnishes, especially when the mercury is not pure.

But it may be said that the blue ointment, which is made with running quicksilver, will not act as a mercurial when rubbed upon the skin. Here too, however, some oxidation takes place in the making of the ointment. Mr. Donovan endeavoured to prove that some of the mercury is always oxidated;[4] and I have generally found a sufficient quantity of oxide to account for the effects.[5]

It has been farther said, in proof of the poisonous action of quicksilver in its metallic state,—that patients, who have taken it for obstructed bowels, have sometimes been salivated. This accident has, I believe, happened in a few instances where the mercury was retained long in the body. But such cases are undoubtedly very rare. Zwinger mentions the case of a man, who took four ounces for colic, and was seized in seven days with salivation.[6] Laborde relates the particulars of another instance where seven ounces taken in fourteen days excited ptyalism, ulceration of the mouth, and great feebleness of the limbs.[7] In the days of Dr. Dover, when the administration of large doses of fluid mercury was a fashionable practice for a variety of purposes, it was alleged to have even sometimes proved fatal; and the case of an actor is specially mentioned, to whom, when convalescent from ague, Dover gave mercury to the amount of two pounds in five days, and who at the close of that period was seized with headache, colic, restlessness, and costiveness, proving fatal in two days; and the whole lower intestines were found black and

  1. Repertorium für die öffentl. und gerichtl. Arzneiwissenschaft, i. 223.
  2. Annalen der Gesetz-gebung, iii. 55.
  3. Journ. de Physiologie, i.
  4. Annals of Philos. xiv. 241, 321.
  5. See my Dispensatory, 1842, p. 500.
  6. Acta Naturæ Curiosorum, Dec. ii. Ann. vi. Obs. 231.
  7. Journal de Médecine, l. 3.