Page:Treatise on poisons in relation to medical jurisprudence, physiology, and the practice of physic (IA treatiseonpoison00chriuoft).pdf/347

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  • perty. Yet it is well known to be a good antiseptic, when applied

topically. The experiments of Klanck, noticed under the head of Arsenic, prove that corrosive sublimate at all events does not retard putrefaction in the bodies of those poisoned with it; and Augustin in his analysis of Klanck's researches infers that it even promotes decay.[1] I have met with one example in the human subject which seems to confirm Augustin's opinion. In the case formerly quoted from the Medical and Physical Journal, which was fatal in four days, the relater found the body forty-two hours after death so putrid, though in the month of January, that the examination of it was very unpleasant, the belly being black, and a very offensive odour being exhaled.[2] Little importance, however, can be attached to a solitary case; for on the contrary Sallin relates a case where the body of a man supposed to have been poisoned with corrosive sublimate was found not decayed, but imperfectly mummified, after sixty-seven days.[3]

It is unnecessary to detail the proofs to be found in the dead body of mercurial salivation having existed during life. They are of course to be looked for in the mouth, and in the adjoining organs. We must not, however, expect to see much appearance of disease in the salivary glands; for according to Cruveilhier, in persons who die of mercurial salivation these glands do not present any trace of inflammation themselves, but merely serous effusion into the cellular tissue around them.[4]

Professor Orfila has made some useful experiments as to the effects of corrosive sublimate on dead intestine, which it may be proper to notice in a few words. When applied in the form of powder to the rectum of an animal newly killed, the part with which it is in contact becomes wrinkled, and as it were granulated, harder than natural, and of alabaster whiteness, intermingled with rose-red streaks, apparently the ramifications of vessels. When the membrane is stretched upon the finger, the wrinkling disappears. The muscular coat is of a snow-white colour, and even the serous coat is white, opaque, and thickened. The parts not in contact with the powder retain their natural appearance, and the line of demarcation between the affected and unaffected portions is abrupt. If the powder is not applied till twenty-four hours after death, the parts it touches become thick, white, and hard; but no red lines are visible. It is easy to draw the distinction between these appearances and the effects of corrosive sublimate during life.

Little need be said of the force of the evidence of poisoning with corrosive sublimate, derived from the morbid appearances. If the gullet, stomach, and colon be all inflamed and ulcerated, and these injuries have taken place during a short illness, the presumption in favour of some form of irritant poisoning will be strong. And the presumption of poisoning with corrosive sublimate will be strong, if

  1. Augustin's Repertorium, B. i. H. ii. 11.
  2. xli. 207.
  3. Journal de Médecine, l. iii. 15, or Recueil Périodique de la Soc. de Méd. vii. 343.
  4. Revue Medicale, 1830, ii.