File:Gene-Disease-Network-Analysis-Reveals-Functional-Modules-in-Mendelian-Complex-and-Environmental-pone.0020284.g004.jpg

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Gene-Disease-Network-Analysis-Reveals-Functional-Modules-in-Mendelian-Complex-and-Environmental-pone.0020284.g004.jpg ‎(661 × 255 pixels, file size: 111 KB, MIME type: image/jpeg)

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English: A network of genes and diseases around Rhabdomyolisis is displayed. The drug Perhexiline is used for treatment of Angina Pectoris and has as therapeutic target CPT13. In addition, it can also target CPT2. Since deficiencies in CPT2 function are associated with Rhabdomyolisis, it can be proposed that Perhexiline causes Rhabdomyolisis through its action on CPT2.
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Source Image file from Bauer-Mehren A, Bundschus M, Rautschka M, Mayer M, Sanz F, Furlong L (2011). "Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases". PLOS ONE. DOI:10.1371/journal.pone.0020284. PMID 21695124. PMC: 3114846.
Author Bauer-Mehren A, Bundschus M, Rautschka M, Mayer M, Sanz F, Furlong L
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current13:47, 23 July 2014Thumbnail for version as of 13:47, 23 July 2014661 × 255 (111 KB)Recitation-botAutomatic upload of media from: doi:10.1371/journal.pone.0020284

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