Particulars are infinite and cannot be measured or embraced, whereas knowledge is a kind of measuring or embracing. The particulars are not always existing, and are subject to change. Hence God's knowledge would be subject to change and disappearance, which is impossible. If God knows particulars how is it that there is often a violation of right and justice in the destinies of individual men? This would argue in God either inability or indifference, both of which are impossible.
Maimonides insists on God's knowledge of all things of which he is the creator, including particulars. And he answers the arguments of the philosophers by saying that their objections are valid only if we assume that God's knowledge is similar to ours, and since with us it is impossible to know the material except through a material organ, it is not possible in God. As we cannot comprehend the infinite; as we cannot know the non-existent, nor the changing without a change in our knowledge, God cannot do so. But it is wrong to assume this. God's knowledge is identical with his essence, which these same philosophers insist is unlike anything else, and unknowable. Surely it follows that his knowledge is also without the least resemblance to our knowledge and the name alone is what they have in common. Hence all the objections of the philosophers fall away at one stroke. We cannot in one act of knowing embrace a number of things differing in species; God can, because his knowledge is one. We cannot know the non-existent, for our knowledge depends upon the thing known. God can. We cannot know the infinite, for the infinite cannot be embraced; God can. We cannot know the outcome of a future event unless the event is necessary and determined. If the event is contingent and undetermined we can only have opinion concerning it, which may or may not be true; we are uncertain and may be mistaken. God can know the outcome of a contingent event, and yet the event is not determined, and may happen one way or the other. Our knowledge of a given thing changes as the thing itself undergoes a change, for if our knowledge should remain the same while the object changes, it would not be knowledge but error. In God the two are compatible. He knows in advance how a given thing will change, and his knowledge never changes, even though that which was at one moment potential and implicit becomes later actual and explicit.
