Page:American Medical Biographies - Kelly, Burrage.djvu/179

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BROWN-SÉQUARD
157
BROWN

Practical Medicine, in which he published his first article on Inhibition, was founded by him in 1874.

In 1856 appeared articles on the functions of the suprarenal capsules. A series of papers which came out in the Boston Medical and Surgical Journal, 1857, were published in a book entitled "Researches in Epilepsy, its Artificial Production in Animals, its Etiology, its Nature, and its Treatment in Man."

A course of "Lectures on the Physiology and Pathology of the Central Nervous System," given at the Royal College of Surgeons of England, May, 1858, was published in Philadelphia, 1860, after appearing in The Lancet in London.

Lectures on the "Diagnosis and Treatment of the Principal Forms of Paralysis of the Lower Extremities," also lectures on the "Diagnosis and Treatment of the Various Forms of Paralytic, Convulsive and Mental Affections considered as Effects of Morbid Alterations of the Blood or of the Brain or of Other Organs," being a combination of the "Gulstonian Lectures" delivered at the Royal College of Physicians, London, 1861, and clinical lectures delivered at the National Hospital for the Paralyzed and Epileptic. In 1868 there appeared in Philadelphia "Lectures on the Diagnosis and Treatment of Functional Nervous Affections."

During 1875–76 he delivered lectures in Dublin and other places on "Anesthesia, Amaurosis and Aphasia caused by Lesions of the Brain," and at the Royal College of Physicians, London, on the "Pathological Physiology of the Brain."

In 1878 he began his course at the Collège de France. From then to the time of his death the Archives de Physiologie, the reports of the "Académie des Sciences," and of the "Société de Biologie" contained the results of his researches "On the Physiology of the Blood-corpuscles," "On Cadaveric Rigidity" and "Muscular Contractions," "On the Influence of Carbonic Acid" and "On the Noxious Effects of Expired Air, Effects Distinct from Those of Carbonic Acid."

In 1889 Brown-Séquard began his experiments "on the internal secretion of glands," and descriptions of his new therapeutic method of subcutaneous injections of organic liquids appeared in the above-mentioned journals and reports.

Among many other papers one may cite the article "Epilepsy" in Quain's "Dictionary of Medicine," and an article in the Forum, New York, 1892, on "Have We Two Brains or One?"

Many honors and appointments came to him. He was one time lecturer before the Royal College of Surgeons of England on the physiology and pathology of the nervous system and Gulstonian lecturer before the Royal College of Physicians, London, and fellow of the faculty of physicians and surgeons, Glasgow. He received the honorary LL.D. from Cambridge University, England, the Lacaze prize from the French Académie des Sciences, and from the same body in 1885 the "grand prix biennal" which elected him member in place of Vulpian. The Royal College of Physicians, London, presented him with the Baly medal in 1886.

From a personal communication from his daughter Mrs. Bolton McCausland.
Dict. of Nat. Biog., Dr. D'Arcy Powell
Archives de Physiologic Normale et Pathologique, Dr. E. Gley. 5th series, vol. vi.
Comptes Rendus de la Société de Biol., 1894.
Nos Grands Medécins, H. Bianchon, 1891.
Lancet, 1894, vol. I, p. 1391.
The Life of Brown-Séquard, Monsieur Berthelot.
Paper read before the Acad. des Sciences, Dec. 19, 1898.
There is a portrait in the town hall, Port Louis, Island of Mauritius, by Serudat de Belzian.

Brown, William (17―–1792)

William Brown, an army doctor, was bom in Scotland, probably Haddingtonshire, where his grandfather had left an entailed estate. William was the grandson of Dr. Gustavus Brown, Sr. (q.v.) of Rich Hill, near Port Tobacco, Maryland, and the son of the Rev. Richard Brown.

He graduated M. D. in 1770 from the University of Edinburgh, where he had been a student, the subject of his thesis being "De Viribus Atmosphæræ."

Settling in Alexandria upon his return home, he soon attained a high professional rank, and being a man of culture and polished manners, became intimate with many of the leading men of the day, among them, Washington, Jefferson and Madison.

At the beginning of the Revolution he entered the service of his country as surgeon to Col. Woodford's regiment of Virginia troops, but on the twentieth of September, 1776, was elected assistant to Dr. Shippen (q.v.), a chief physician of the Continental Army. Upon the recommendation of Dr. Hugh Mercer (q.v.), he was elected by Congress, February 7, 1778, to be physician-general of the middle department in place of Dr. Rush (q.v.), a position he resigned on July 21, 1780, returning to private practice.

In resigning he forfeited his right to be paid in bounty lands, but so highly were his services