OTT 869 OUCHTERLONY strangers, he became eloquent when warmed by the discussion of any topic in which he took interest. James J. Walsh. Amer. luur. Med. Sci., 1881, vol. Lxx-vii, J. J. Woofhvaiil. Brit. Med. Jour., Lond., 1S81, vol. ii. Tidskr. i. mil. Helsov., Stockholm, 1S82, vol. vii. Trans. Amer. Med. Asso., Pliila., ISSl, vol. xxxii. Ott, Isaac (1S47-1916) Isaac Ott, writer and teacher of physiology, was born in Northampton County, Pennsyl- vania, November 30, 1847. His education was obtained at Lafayette College and at the Uni- versity of Pennsylvania, where he took his M. D. in 1869, with a thesis on typhoid fever. After ser-i'ing as a resident at St. Mary's Hos- pital he went abroad to study at the universi- ties of Leipsic, Wiirtzburg and Berlin, and returning to America in 1873, he became lec- turer on physiology at the University of Penn- sylvania and held the position until 1878. In 1876 he settled in Easton, Pennsylvania, where he remained. Dr. Ott held the position of fellow in biology at the Johns Hopkins Uni- versity in 1879 and in the same year was lec- turer on physiolog}' in the Medico-Chirurgical College of Philadelphia, becoming professor in 1894 and dean of the faculty in 1895. He was a most voluminous writer for the medical journals, largely on physiological topics, there being fifty-one titles in the catalogue of the Surgeon-General's Library. His largest work w^as his book on "The Action of Medicines," 168 pages, published in Phila- delphia in 1898. His last work was a paper on Internal Secretions, which appeared in 1910. He was consulting neurologist to the State Hospital at Norristown, Pennsylvania, and he was at one time president of the American Neurological Association. He died at his home in Easton. January 1, 1916, survived by his widow. Katherine K. Ott. Jour. Amer. Med. Asso., Ian. 15, 1916. Phys. and Surgs. of U. S., W. B. Atkinson. 1878. Otto, John Conrad (1774-1844) This physician to the Pennsylvania Hospital was the first in America to call attention to hemophilia in an article entitled "An account of an Hemorrhagic Disposition existing in certain families," that was published in the Medical Rel^ository, New York, in 1803. Dr. Otto's grandfather, a physician, emigrated from Germany and settled in Philadelphia in 1752. Having a European literary and medical training, he was highly thought of, served in the Revolution, attended the American army at Valley Forge and had charge of the hospital there during the winter of 1778. Dr. Otto's father. Dr. Eodo Otto, died of consumption at the age of thirty, leaving his widow with three small children, John being the youngest. John, who was born near Woolbridge, New Jersey, March 15, 1774, received an A. B. at Princeton College in 1792 and then entered the office of Benjamin Rush (q. v.) in Philadelphia as a student, in time becoming a favorite pupil, and getting his M. D. from the University of Pennsylvania in 1796. In 1798 he caught the yellow fever during the epidemic of that time and, on recovery, in the same year, became one of the physicians to the Philadelphia Dispen- sary, serving for a period of five years. In 1802 he married Eliza Todd, daughter of Alexander Todd, a Philadelphia merchant, and they had nine children. On the death of Dr. Rush, in 1813, Dr. Otto was appointed one of the physicians to the Pennsylvania Hospital, a position he held for twenty-two years, giving him an opportunity to become known as a forceful and clear clin- ical teacher and writer. His article on hemophilia, published in 1803, contained "some singular facts in regard to the occurrence of the most alarming, and even fatal, hemor- rhages, after slight wounds or scratches, in the male descendants of a woman nained Smith, in the vicinity of Plymouth, New Hampshire. The females of the family were exempt from the idiosyncrasy, but still were capable of transmitting it to their male children." In 1805 he published another paper on the same sub- ject in Coxe's Medical Museum, detaifing the history of four fatal cases of hereditary hemorrhage occurring in the family of Ben- jamin Binny, of Maryland. Other papers on a variety of subjects are to be found in the Eclectic Repertory, and North American Med- ical and Surgical Journal. Dr. Otto was physician to the Orphan Asylum and to the Magdalen Asylum for many years ; he was a Fellow of the College of Physicians, holding the office of censor, and from 1840 until his death that of vice-president. In his practice he confined himself to flie practice of medicine, avoiding surgery and obstetrics ; in his social relations he was re- markable for simplicity and ease of manner; he was deeply religious, reading the Scriptures morning and evening, and favoring the Presby- terian sect. His eminently useful career was brought to a close by heart disease, June 26, 1844, in the 71st year of his age. Bio^. Memoir of John C. Otto, by Isaac Parrish, Phila., 1845, 20 pages. Ouchterlony, John Ard!d (1838-1908) He was born in Gothenborg, Smalend, Swe- den, June 24. 1838, his father, a captain in the
