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In order to ascertain whether the boy, after feeling so slight an affection of the system from the Cow-pox virus, was secure from the contagion of the Small-pox, he was inoculated the 1st of July following with variolous matter, immediately taken from a pustule. Several slight punctures and incisions were made on both his arms, and the matter was carefully inserted, but no disease followed. The same appearances were observable on the arms as we commonly see when a patient has had variolous matter applied, after having either the Cow-pox or the Small-pox. Several months afterwards, he was again inoculated with variolous matter, but no sensible effect was produced on the constitution.
Here my researches were interrupted till the spring of the year 1798, when from the wetness of the early part of the season, many of the farmers' horses in this neighbourhood were affected with sore heels, in consequence of which the Cow-pox broke out among several of our dairies, which afforded me an opportunity of making further observations upon this curious disease.
