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Among these Robert F. Jenner did not receive the infection. The arms of the other three inflamed properly and began to affect the system in the usual manner; but being under some apprehensions from the preceding Cases that a troublesome erysipelas might arise, I determined on making an experiment with the view of cutting off its source. Accordingly after the patients had felt an indisposition of about twelve hours, I applied in two of these Cases out of the three, on the vesicle formed by the virus, a little mild caustic, composed of equal parts of quick-lime and soap, and suffered it to remain on the part six hours[1]. It seemed to give the children but little uneasiness, and effectually answered my intention in preventing the appearance of erysipelas. Indeed it seemed to do more, for in half an hour after its application, the indisposition of the children ceased[2]. These precautions were perhaps unnecessary as
