292 DIGEST OF LITERATURE;
HYPERTROPHIES AND ATROPHIES.
ARTHUR VAN HARLINGEN, M.D.
Case of congenital and progressive hypertrophy of the right upper extremity. — Osler, in connection with a brief no- tice of the literature of the subject, which only includes thirteen cases aside from enlargement of single fingers and toes, gives notes of a case occurring in a girl 9 years of age at the time of exam- ination. The enlargement of the arm was quite noticeable at birth, the hand being deformed, with the fingers flexed. Gradual and pro- gressive growth of the limb occurred with the development of the child. On examination the limb appeared equal in size to that of a medium-sized man. The enlargement extended to the muscles of the shoulder. The skin on the limb was normal ; the tempera- ture the same on both sides ; the muscular power of the limb was markedly increased. — -Journal of Anatomy and Physiology, vol. xiv., 1879, P- lo-
Chloasma uterinum. — Dr. P. J. Murphy reports the case of a woman of light complexion, who at the sixth month of pregnancy showed patches of dark-brown pigment extending from the roots of the hair across the forehead and down the cheeks. The entire ex- posed surface was of a dusky-olive appearance, and all parts of the body examined presented the same general aspect, mottled with darker patches and fading off at intervals. There was marked enlarge- ment, with follicular ulceration of the os and cervix uteri. After delivery, which took place at the eighth month, the pigmentation slowly disappeared, at least in part. Dr. Murphy calls attention to Gueneau de Mussy's statement (^Rev. Medicale, Feb. 1879) that any irritation or lesion of the nerves which supply the supra-renal capsules, in whatever part of the abdomen it may originate, will give rise to pigmentation. — The Obstetric Gazette, Cincinnati, Jan. 1880, p. 294.
A case of ichthyosis of unusual character. — Dr. H. Radcliffe Crocker, for the late Dr. Tilbury Fox, reports the case of a weakly boy of 10, whose mother noticed upon him at the time of his birth an appearance of bruising in three places on the thighs, the left being the worst, and presenting raw-looking places as large as a finger. There were other raw-looking places over the body and limbs. These healed up in about seven weeks, and a warty growth began first to appear about the sores, but grad- ually spread over wider areas until the body was nearly covered with it when seven years old. From that time it remained stationary. When examined, he was found covered with irregularly-disposed groups of warty and horny-looking growths from the crown of his head to the soles of his feet, with wide areas of healthy skin, how- ever, between. The patches, which were described as raw at birth, were covered with thin cicatrices, except on the scalp, where they
