as may be seen, even this impression was left to be collected from the general tone of the conclusion, and not from any specific words—which are in no instance at variance with the literal truth.—In no long time after that paper was written, I became sensible that the effort which remained would cost me far more energy than I had anticipated: and the necessity for making it was more apparent every month. In particular I became aware of an increasing callousness or defect of sensibility in the stomach; and this I imagined might imply a schirrous state of that organ either formed or forming. An eminent physician, to whose kindness I was at that time deeply indebted, informed me that such a termination of my case was not impossible, though likely to be forestalled by a different termination, in the event of my continuing the use of opium. Opium therefore I resolved wholly to abjure, as soon as I should find myself at liberty to bend my undivided attention and energy to this purpose. It was not however until the 24th of June last that any tolerable concurrence of facilities for such an attempt
