few years later, described exactly the morbid anatomy of typhoid fever. Stewart's experience in the post-mortem room at Glasgow led him to believe firmly in the distinction between the two fevers, and in this essay he states clearly, from his own observation of cases, their differences in origin, cause, course, symptoms, and anatomical lesions, while his remarks against the use of purgatives in typhoid fever entitle him to further distinction as one who has contributed to the saving of many lives by pointing out the danger of what had been a prevalent method of treatment. Sir William Jenner's celebrated papers in 1849, 1850, and 1853 are written on the same lines as Stewart's; but as they were based on a far more extended field of personal observation they had more public effect, and are justly regarded as having finally settled the question. Stewart was an elder in the presbyterian church and wrote in 1843 ‘Divide and Conquer,’ and numerous other pamphlets relating to the church of Scotland. He died unmarried at his house in Grosvenor Street on 17 July 1883. He did not attain to large practice, but both his character and attainments were esteemed by the physicians of his time.
[Memoir by Dr. W. Cayley, New Sydenham Society, vol. cx. 1884; Dr. Norman Moore's Pathological Anatomy of Diseases, 1889; Hilton Fagge's Principles and Practice of Medicine, 2nd edit. 1888; Edinburgh Medical and Surgical Journal, October 1840; obituary notice by John Marshall in an address to the Royal Medical and Chirurgical Society, Transactions. vol. lxvi. 1884; Works.]
STEWART, ANDREW, first Lord Avandale or Avondale (d. 1488), chancellor of Scotland, was, according to the latest authorities, eldest son of Walter, second son of Murdac Stewart, second duke of Albany [q. v.] His mother was apparently a daughter of (Sir Duncan) Campbell of Lochow, ancestor of the Argyll family, but her marriage with Walter Stewart was for some reason considered unlawful. Hence in 1472 and 1479 Andrew obtained from the crown letters of legitimation to himself and two brothers, Arthur and Walter. The date of his birth cannot be stated, but he and a younger brother, Murdach, had both been knighted in England before 12 July 1437 (Rymer, Fœdera, x. 672). It is probable he was educated in that country and returned to Scotland after the death of James I, as he was a member of the general council held at Stirling in August 1440 (Acts of the Parliaments of Scotland, ii. 56).
Sir Andrew Stewart rose in the favour of the young king, James II, and apparently held office in the royal household. In 1456 he received a grant of the lands of Strathavon, Avondale or Avandale, forfeited by William Douglas, eighth earl of Douglas [q. v.], and was also made warden of the west march and keeper of the castle of Lochmaben. He was created Lord Avandale before 11 June 1457 (Rymer, Fœdera, xi. 397), and appointed to the office of chancellor of Scotland in 1460. He continued to hold this post during the next reign, and was for a time one of the lords of regency during the minority of James III. Stirling Castle was placed in his hands, and he was on more than one embassy to England. He took a very prominent part in the negotiations with the king of Denmark for the hand of his daughter Margaret as wife to the Scottish king (Torfæus, Orcades, 1715, p. 193), and was specially successful in obtaining the cession to Scotland of the islands of Orkney and Shetland, then belonging to Denmark.
In May 1471 Avandale obtained a life-rent grant over the earldom of Lennox, and he also got other lands; but little is recorded of him save the duties of his office until 1479, when by order of the king he besieged the castle of Dunbar, rebelliously fortified against the crown by the king's brother, Alexander Stewart, duke of Albany [q. v.] It soon surrendered. In 1482, when James III declared war against England, Avandale is said to have joined those nobles who refused to advance beyond Lauder, and who warded the king in Edinburgh Castle. This is believed to have been done in the interest of Albany. Avandale certainly was one of those who, on 2 Aug. 1482, effected an agreement between James III and Albany (Rymer, Fœdera, xii. 160), and some days later he was deposed from the chancellorship. The reason is involved in obscurity; but as one historian (Lindsay of Pitscottie) expressly names him among the conspirators at Lauder, the king may have been suspicious of his loyalty, or he may have refused to enter into all the plans of those who held the king in durance. Be this as it may, though he was never again chancellor, he took part in public affairs in March 1483, and he sat in the parliaments which deprived Albany of his office of lieutenant-general and pronounced forfeiture against him. Avandale was one of the ambassadors to France in July 1484 who renewed the ancient league with that country, and in the following month he was named as an envoy to England (ib. xii. 230), but did not go. After this he appears to have retired from public life, though he acted as an auditor of exchequer and witnessed a few royal charters, the latest dated
