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- UNADILLA (New York): President Dwight describes, 12, 155–160; Erie Canal stops growth of, 61.
- Union College Guards, celebrate opening of Erie Canal, 14, 145.
- Uniontown (Pennsylvania): Pennsylvania compels United States government to lay Cumberland Road through, 10, 54; early taverns at, 158.
- United States Hotel, 10, 160.
- United States: improves navigation of Ohio River, 9, 189–220; subscribes for stock in Portland Canal, 203–205; builds Cumberland Road, 10, 18–90; opens Zane's Trace through Ohio, 11, 156–158; surveys a route for Chesapeake and Ohio Canal, 13, 77–78; subscribes stock in Chesapeake and Ohio Canal, 112; refuses to take stock in Baltimore and Ohio Railway, 113–114; proposed to aid Erie Canal with funds accruing from sale of Michigan lands, 14, 58–59.
- Upland House, 10, 160.
- Utica (New York): strategic position of, 12, 99; Bigelow describes, 121–126; inaugural celebration at completion of Erie Canal, 14, 143–144.
