ever that similar effects should not be produced by it in situations which differ apparently but little from those designated as the seats of the disorder, for instance in the valley of Sŏnōră, nearly parallel with that of Ōpŏsūră, and in Cūlĭăcān, which is almost on the same line with Cŏsălā. Perhaps the effect diminishes as the distance from the Sierra increases; for Cŏsălā is only five leagues from the foot of the Cordillera, and may consequently be more immediately under the influence of the causes calculated to engender the disease. This supposition is confirmed by the increased violence of the affection at Santa Ana, a rancho, where the ascent towards the Table-land commences, and where all the inhabitants without exception are victims to this disgusting complaint.
From Cŏsălā to the Capital, or the Central States of the Republic, there are two routes; the one by Rosario, the river Cañas, and Guădălajāră, which is impassable during the rainy season, the other due East from Cŏsălā, across the Sierra Madre to Durango. By the first of these Colonel Bourne entered Cinaloa, and he quitted it by the second, the rains having commenced at Cūlĭăcān on the 24th of June, and cut off all communication by the coast in the course of a very few days. He describes the ascent to the Table-land as full of difficulties, and extremely precipitous, but he nevertheless contrived to reach Durango in eight days by a road which crosses the mountains between Păpăsqŭiāro and Gūārĭsămĕy,
