Page:NIOSH Manual of Analytical Methods - 1010.pdf/1

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OSHA:  

5 ppm (skin)

NIOSH:  

lowest feasible (carcinogen)

ACGIH:  

2 ppm (skin) (carcinogen)
(1 ppm = 3.78 mg/m3 @ NTP

PROPERTIES:  

liquid; d 1.1812 g/mL @ 20 °C;
BP 117.9 °C; MP 25.6 °C;
VP 1.67 kPa (12.5 mm Hg;
16,400 ppm) @ 20 °C; explosive range

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SYNONYMS: chloropropylene oxide; 1-chloro-2,3-epoxypropane; chloromethyloxirane

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SAMPLING

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SAMPLER:  

SOLID SORBENT TUBE
(coconut shell charcoal, 100 mg/50 mg)

FLOW RATE:  

0.01 to 0.2 L/min

VOL-MIN:  

2 L @ 5 ppm

-MAX:  

30 L

SHIPMENT:  

routine

SAMPLE STABILITY:  

at least 2 weeks @ 25 C [1]

BLANKS:  

2 to 10 field blanks per set

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ACCURACY

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RANGE STUDIED:  

12 to 43 mg/m3 [2]
(20-L samples)

BIAS:  

4.2%

OVERALL PRECISION (SrT):  

0.057 [2]

ACCURACY:  

± 14.3%

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MEASUREMENT

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TECHNIQUE:  

GAS CHROMATOGRAPHY, FID

ANALYTE:  

epichlorohydrin

DESORPTION:  

1 mL CS2; stand 30 min

INJECTION VOLUME:  

5 µL

TEMPERATURE-INJECTION:  

175 °C

-DETECTOR:  

215 °C

-COLUMN:  

135 °C

CARRIER GAS:  

N2 or He, 20 mL/min

COLUMN:  

1.8 m x 2-mm ID glass; 80/100 Chromosorb 101 [1]

CALIBRATION:  

epichlorohydrin in CS2

RANGE:  

0.04 to 1.2 mg per sample [2]

ESTIMATED LOD:  

1.0 µg per sample

PRECISION (Sr):  

0.031 [2]

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APPLICABILITY: The working range is 0.5 to 16 ppm (2 to 60 mg/m3) for a 20-L air sample.

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INTERFERENCES: None identified.

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OTHER METHODS: This is Method S118 in a revised format [3]. A similar method appears in the criteria document [4].

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NIOSH Manual of Analytical Methods (NMAM), Fourth Edition