DIOXANE
C4H8O 2
MW: 88.11
METHOD: 1602, Issue 2
CAS: 123-91-1
1602
RTECS: JG8225000
EVALUATION: FULL
OSHA : 100 ppm (skin) NIOSH: 1 ppm/30 min; carcinogen ACGIH: 25 ppm (skin); carcinogen (1 ppm = 3.60 mg/m 3 @ NTP)
Issue 1: 15 May 1985 Issue 2: 15 August 1994
PROPERTIES: liquid; d 1.0337 g/mL @ 20 °C; BP 101 °C; MP 12 °C VP 3.9 kPa (29 mm Hg; 3.8% v/v) @ 20 °C; explosive range 2 to 22% v/v in air
SYNONYMS: dioxan; p-dioxane; 1,4-diethylene dioxide; diethylene ether
SAMPLING SAMPLER:
MEASUREMENT
SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)
TECHNIQUE:
GAS CHROMATOGRAPHY, FID
ANALYTE:
dioxane
DESORPTION:
1 mL CS 2, 30 min
FLOW RATE: 0.01 to 0.2 L/min VOL-MIN: -MAX: SAMPLE STABILITY:
BLANKS:
0.5 L @ 100 ppm 15 L
INJECTION VOLUME:
>1 week @ 25 °C >6 weeks @ -10 °C
TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:
2 to 10 field blanks per set
CARRIER GAS:
He, 30 mL/min (60 psig)
COLUMN:
6 m x 3-mm stainless steel packed with 10% FFAP on 80/100 mesh Chromosorb W-HP Chromosorb W-HP
CALIBRATION:
solutions of dioxane in CS 2 with internal standard
RANGE:
0.2 to 7 mg per sample [1,2]
ACCURACY RANGE STUDIED: BIAS:
5 µL 225 °C 250 °C 75 °C
3
157 to 660 mg/m [1] (10-L samples) + 9%
ESTIMATED LOD: 0.01 mg per sample [3]
ˆ ): 0.054 [1] OVERALL PRECISION (S rT ACCURACY:
± 18.7
PRECISION (Sr):
0.017 [1]
APPLICABILITY: The working range is 5.5 to 190 ppm (20 to 700 mg/m 3) for a 10-L air sample.
INTERFERENCES: None known. An alternate GC column is 30 m x 0.32-mm ID fused silica capillary coated with 1 µm DB-5 [3].
OTHER METHODS: This method combines and replaces S360 [4] and P&CAM 127 [5] for dioxane. A similar method appears in the dioxane criteria document [6].
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
