METHYL ETHYL KETONE CH3 COCH2 CH3
MW: 72.11
METHOD: 2500, Issue 2
CAS: 78-93-3
EVALUATION: FULL
OSHA : 200 ppm NIOSH: 200 ppm: STEL 300 ppm ACGIH: 200 ppm: STEL 300 ppm (1 ppm = 2.95 mg/m3 @ NTP)
PROPERTIES:
2500
RTECS: EL6475000 Issue 1: 15 February 1984 Issue 2: Rev., 15 May 1996 liquid; d 0.805 g/mL @ 20 °C; BP 79.6 °C; MP ! 86 °C; VP 13 kPa (100 mm Hg; 13% v/v) @ 25 °C; explosive range 2 to 10% v/v in air
SYNONYMS: 2-butanone; MEK
SAMPLING SAMPLER:
SOLID SORBENT TUBE (beaded carbon, ~150 mg/~75 mg)
FLOW RATE:
0.01 to 0.2 L/min
VOL-MIN: -MAX:
0.25 L @ 200 ppm 12 L
SHIPMENT:
routine
MEASUREMENT TECHNIQUE:
GAS CHROMATOGRAPHY, FID
ANALYTE:
methyl ethyl ketone (MEK)
DESORPTION:
1 mL CS2 ; stand 30 min
INJECTION VOLUME:
5 :L
SAMPLE STABILITY:
at least 90 days @ - 5 °C [1]
TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:
BLANKS:
2 to 10 field blanks per set
CARRIER GAS:
N2 or He, 25 mL/min
COLUMN:
glass or stainless steel, 4 m x 2-mm ID; 20% SP-2100/0.1% Carbowax 1500 on Supelcoport 100/120
CALIBRATION:
MEK solutions in CS 2
RANGE:
0.15 to 5 mg per sample
ACCURACY RANGE STUDIED:
75 to 2250 mg/m3 [1]
BIAS:
not significant [1]
OVERALL PRECISION (Ö r T ):
0.038 [1]
ACCURACY:
± 7.4%
250 °C 300 °C 55 to 75 °C
ESTIMATED LOD: 4 :g per sample [2,3] PRECISION (þ r ):
0.04 [1]
APPLICABILITY: The working range is 17 to 560 ppm (50 to 1650 mg/m3 ) for a 3-L air sample. The method is applicable to 15-min samples. This method was developed to give improved sample stability compared to conventional charcoal tubes [3,4]. Side-by-side comparisons of this method and Method S3 were made in a sporting goods manufacturing plant in which MIBK, THF, and toluene were also present. This method has also been used successfully for methyl isobutyl ketone [1] and acetone [5].
INTERFERENCES: Under the given conditions, acetone and isopropanol have retention times similar to MEK. Mass spectrometry and other GC columns, e.g., SP-1000, or 30 m x 0.32-mm WCOT capillary coated with 1 :m DB-1, are aids to resolving interferences.
OTHER METHODS: This method is similar, except for the sampler, to Methods P&CAM 127 [6] and S3 [7,8], which it replaces.
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition
