GLUTARALDEHYDE
O=CH(CH2)3CH=O
MW: 100.12
METHOD: 2531, Issue 2
CAS: 111-30-8
2531
RTECS: MA2450000
EVALUATION: FULL
OSHA : C 0.2 ppm NIOSH: C 0.2 ppm; Group I Pesticide ACGIH: C 0.2 ppm (1 ppm = 4.09 mg/m 3 @ NTP)
PROPERTIES:
Issue 1: 15 May 1989 Issue 2: 15 August 1993
oil; d 0.72 g/mL @ 20 °C; BP 188 °C; MP - 14 °C; VP 2.2 kPa (17 mm Hg) @ 20 °C
SYNONYMS: glutaric dialdehyde; 1,5-pentanedial.
SAMPLING SAMPLER:
FLOW RATE:
SOLID SORBENT TUBE (10% 2-(hydroxymethyl)piperidine on XAD2, 120 mg/60 mg: Supelco ORBO-23 or equivalent) 0.01 to 0.08 L/min, or 0.2 L/min for 20 min
VOL-MIN: -MAX:
4 L @ 0.2 ppm 39 L
SHIPMENT:
routine
SAMPLE STABILITY:
at least 5 weeks @ 25 °C [1]
FIELD BLANKS:
2 to 10 field blanks per set
MEASUREMENT TECHNIQUE:
GAS CHROMATOGRAPHY, FID
ANALYTE:
oxazolidine derivative of glutaraldehyde
DESORPTION:
2 mL toluene; 60 min ultrasonic
INJECTION VOLUME:
1 µL splitless; split vent time 30 s
TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:
CARRIER GAS:
He, 0.5 mL/min; makeup 2.9 mL/min
COLUMN:
capillary, 10 m x 0.25-mm, 5% phenyl, 95% methyl polysiloxane (DB-5 or equivalent)
CALIBRATION:
standard glutaraldehyde solutions spiked on sorbent
RANGE:
3 to 180 µg per sample [1]
MEDIA BLANKS: 10 per set
ACCURACY RANGE STUDIED:
0.8 to 9 mg/m 3 [1] (22-L samples)
BIAS:
0.3%
ˆ ): 0.087 [1] OVERALL PRECISION (S rT ACCURACY:
250 °C 280 °C 1 min @ 70 °C; 20 °C/min; hold 2 min @ 290 °C
ESTIMATED LOD: 1 µg per sample [2] PRECISION (Sr):
0.093 [2] @ 5 to 50 µg per sample [1]
± 17.4%
APPLICABILITY: The working range is 0.03 to 2 ppm (0.14 to 8 mg/m 3) for a 22-L air sample; the method is sensitive enough for ceiling determinations. The method is suitable for the simultaneous determination of furfural and glutaraldehyde.
INTERFERENCES: None have been observed.
OTHER METHODS: This is a new method. A wide-bore 10-m capillary column is an alternate chromatographic column.
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/93
