TRIETHYLENETETRAMINE See ETHYLENEDIAMINE, Method 2540, for Procedure (NH2CH2CH2NHCH2)2
MW: 146.2
METHOD: 2540, Issue 2
CAS: 112-24-3
RTECS: YE6650000
EVALUATION: UNRATED
OSHA : no PEL NIOSH: no REL ACGIH: no TLV (1 ppm = 5.98 mg/m 3)
PROPERTIES:
Issue 1: 15 May 1989 Issue 2: 15 August 1994
liquid; d 0.98 g/mL @ 20 °C; BP 277.4 °C; VP unknown; flash point 118 °C
SYNONYMS: triethylenetetramine: TETA; trientine; N,N-bis(2-aminoethyl)-1,2-diaminoethane; 3,6-diazaoctane-1,8-diamine
SAMPLING SAMPLER:
MEASUREMENT TECHNIQUE:
HPLC, UV DETECTION
ANALYTE:
naphthylisothiourea derivative of analytes
FLOW RATE: 0.01 to 0.1 L/min [1]
DESORPTION:
2 mL dimethylformamide (DMF), ultrasonic 30 min
VOL-MIN: -MAX:
1 L @ 10 ppm 20 L
INJECTION VOLUME: 10 µL
SHIPMENT:
routine
COLUMN:
10-µm radial cyano, 10 cm x 8-mm ID in Waters RCM-100 radial compression mode
MOBILE PHASE:
50/50 isoctane/isopropanol at 3 mL/min
CALIBRATION:
standard solutions of derivatives in DMF
SAMPLE STABILITY: BLANKS:
SOLID SORBENT TUBE (1-naphthylisothiocyanatecoated XAD-2, 80 mg/40 mg)
>30 days @ 20 °C [2] 2 to 10 field blanks per set
ACCURACY
RANGE: 0.016 to 8 mg/m 3; (10-L samples)
RANGE STUDIED:
ˆ ): OVERALL PRECISION (S rT
1 to 119 µg per sample
ESTIMATED LOD: 0.3 µg per sample PRECISION (Sr):
0.018
0.06 [1]
BIAS:
-1.9%
ACCURACY:
±13.7%
APPLICABILITY: The working range for TETA is 0.08 to 160 mg/m 3 for a 10-L air sample. This method is the result of evaluation [2] of OSHA Method #60 for DETA, EDA, TETA [1]. The theoretical capacity of each front section is 1.6 mg of TETA.
INTERFERENCES: Other primary or secondary amines may react with the sampler coating reagent, and thereby reduce the sampler capacity.
OTHER METHODS: This replaces NIOSH Method P&CAM 276 [3]. The method of Anderson, et al., for EDA [4] is an alternate method using thiourea derivatization and HPLC analysis.
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
