CRESOL (all isomers) and PHENOL
CH3C6H4OH C6H5OH
MW: 108.14 94.11
METHOD: 2546, Issue 1
CAS: 1319-77-3 108-95-2
2546
RTECS: GO5950000 SJ3325000
EVALUATION: PARTIAL
OSHA : Table 1 NIOSH: ACGIH:
Issue 1: 15 August 1994
PROPERTIES: Table 1
SYNONYMS: o-cresol: 2-methylphenol; CAS #95-48-7; m-cresol: 3-methylphenol; CAS #108-39-4; p-cresol: 4-methylphenol; CAS
- 106-44-5.
phenol: carbolic acid; hydroxybenzene SAMPLING SAMPLER:
SOLID SORBENT TUBE (XAD-7, 100 mg/50 mg)
FLOW RATE:
0.01 to 0.1 L/min
VOL-MIN: -MAX:
1 L @ 5 ppm 24 L
SHIPMENT:
routine
MEASUREMENT TECHNIQUE:
GAS CHROMATOGRAPHY, FID
ANALYTE:
cresol isomers/phenol
DESORPTION:
2 mL methanol; sonicate
INJECTION VOLUME:
1 µL (split 20:1)
SAMPLE STABILITY:
at least 1 week @ 25 °C [1]
TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:
BLANKS:
2 to 10 field blanks per set
CARRIER GAS:
He, 1 mL/min
COLUMN:
Stabilwax DA fused silica capillary, 30 m, 0.32-mm ID, 0.25-mm film or equivalent
CALIBRATION:
standard solutions of analytes in methanol 20 to 800 µg per sample
ACCURACY
250 °C 300 °C 160 - 225 °C (3 °C/min)
RANGE STUDIED:
not studied
RANGE:
BIAS:
not determined
ESTIMATED LOD: 1 to 3 µg per sample
ˆ rT): not determined OVERALL PRECISION (S ACCURACY:
PRECISION (Sr):
0.028 [1]
not determined
APPLICABILITY: The working range is 0.25 to 15 ppm (1 to 60 mg/m 3) for cresols and phenol in a 20-L air sample.
INTERFERENCES: None identified. A DB-wax fused silica capillary column is an alternate column.
OTHER METHODS: This method uses a sampler similar to that of OSHA 32 [1] and replaces methods 2001 (Cresols) [2] and 3502 (Phenol) [3]. Analysis of the sample extracts can also be done by HPLC/UV [1,4].
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
