KETONES II FORMULAS: TABLE 1
MW: TABLE 1
METHOD: 2553, Issue 1
CAS: TABLE 1
EVALUATION: PARTIAL
PROPERTIES:
OSHA : Table 1 NIOSH: Table 1 ACGIH: Table 1
COMPOUNDS/ SYNONYMS:
2553
(1) 2-Heptanone: Methyl-n-amyl ketone (2) 3-Heptanone: Ethyl butyl ketone (3) Mesityl oxide: 4-Methyl-3-penten-2-one
SOLID SORBENT TUBE (Anasorb CMS, 150/75 mg) [1]
FLOW RATE:
0.01 to 0.2 L/min
VOL-MIN: -MAX:
1L 25 L
SHIPMENT:
Routine
SAMPLE STABILITY:
30 days @ 5°C [1]
BLANKS:
10% of samples ACCURACY
RANGE STUDIED:
Not Determined.
BIAS:
Not Determined.
OVERALL PRECISION ( Ö r T ):
Not Determined.
ACCURACY:
Not Determined.
Issue 1: 15 March 2003
Table 1
(4) 5-Methyl-3-heptanone: Ethyl amyl ketone (5) Camphor: 2-Camphanone, Gum Camphor
SAMPLING SAMPLER:
RTECS: TABLE 1
MEASUREMENT TECHNIQUE:
GAS CHROMATOGRAPHY, FID
ANALYTE:
Table 1
DESORPTION:
1 mL of 2% isopropanol in CS 2 with agitation [1]
INJECTION VOLUME:
1 µL
TEMPERATURE -INJECTION: -DETECTOR: -COLUMN:
225°C [1] 300°C [1] 55°C (3 min hold) to 190°C (8°C/min) [1]
CARRIER GAS:
Helium (4.8 mL/min) [1]
COLUMN:
Capillary, fused silica, 30-m x 0.32-mm ID; 1.00 µm film crossbond trifluoropropylmethyl polysiloxane or equivalent [1]
CALIBRATION:
Solutions of analytes in desorption solvent
RANGE:
See Table 2 [1]
ESTIMATED LOD: See Table 2 [1] PRECISION ( þ r ):
See Table 2 [1]
APPLICABILITY: For a 10-L air sample, the working range for 2-heptanone is 0.86 to 24.8 ppm (4.0 to 121 mg/m3 ); for 3heptanone is 0.43 to 12.9 ppm (2.0 to 60.3 mg/m3 ); for mesityl oxide is 0.22 to 6.89 ppm (0.9 to 22.6 mg/m3 ); for 5-methyl-3heptanone is 0.21 to 6.29 ppm (1.1 to 33.0 mg/m3 ); and for camphor is 0.14 to 4.84 ppm (0.9 to 30.2 mg/m3 ) [1].
INTERFERENCES:
Any compound having the same retention times as the analytes of interest.
OTHER METHODS: This method was developed as part of an update of NIOSH Method 1301 (Issue 2, 15 August 1994) [2] which combined the NIOSH Methods: S10, S12, S13, S15, and S16 from the 2nd edition of the NIOSH Manual of Analytical Methods [3,4]. Improvements included: lower LOD/LOQ values, improved DE recovery results (at lower levels) by using Anasorb CMS and 2% IPA in CS 2 , a 30 day storage stability study, and the replacement of the packed column with a Rtx-200 fused silica capillary column.
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition
