PENTACHLOROPHENOL
C6Cl5OH
MW: 266.35
METHOD: 5512, Issue 2
CAS: 87-86-5
5512
RTECS: SM6300000
EVALUATION: FULL
OSHA : 0.5 mg/m 3 (skin) NIOSH: 0.5 mg/m 3 (skin); Group I Pesticide ACGIH: 0.5 mg/m 3 (skin)
PROPERTIES:
Issue 1: 15 May 1989 Issue 2: 15 August 1994
solid; MP 190 °C; d 1.978 g/mL @ 22 °C; VP 16 Pa (0.12 mm Hg; 1700 mg/m 3) @ 100 °C
SYNONYMS: penta; PCP
SAMPLING SAMPLER:
FILTER + BUBBLER (mixed cellulose ester membrane with stainless steel backup screen/ethylene glycol)
FLOW RATE: 0.5 to 1.0 L/min
MEASUREMENT TECHNIQUE:
HPLC, UV DETECTION
ANALYTE:
pentachlorophenol
EXTRACTION:
10 mL methanol
VOL-MIN: -MAX:
48 L @ 0.5 mg/m 3 480 L
INJECTION VOLUME:
20 µL
SHIPMENT:
place filter in bubbler containing 15 mL ethylene glycol after sampling
MOBILE PHASE:
60% methanol/40% water, 1.5 mL/min
COLUMN:
µ-Bondapak C 18, 10-µm particle size, 30 cm x 3.9-mm ID
DETECTOR:
UV @ 254 nm
SAMPLE STABILITY:
at least 8 days @ 25 °C
BLANKS:
2 to 10 field blanks per set CALIBRATION: standard solutions of pentachlorophenol n i ethylene glycol and methanol ACCURACY RANGE:
RANGE STUDIED: BIAS:
0.265 to 1.130 mg/m 3 [1] (180-L samples) 3.0%
ˆ rT): 0.072 OVERALL PRECISION (S ACCURACY:
24 to 270 µg per sample [1]
ESTIMATED LOD: 8 µg per sample [2] PRECISION (Sr):
0.051 @ 45 to 180 µg per sample [1]
± 15% (12-28%)
APPLICABILITY: The working range is 0.13 to 11 mg/m 3 for a 180-L air sample. This method is also applicable to STEL measurements using a 15-L sample. The method has been used to sample for pentachlorophenol in the presence of 2,3,4,6tetrachlorophenol at a lumber yard [3].
INTERFERENCES: None identified.
OTHER METHODS: This revises Method S297 [2]. An independent analytical method provided by Vulcan Materials Co. [4] using a sampling train consisting of Zefluor filter and silica gel tube and HPLC analysis was used by a NIOSH contractor [5] f or analyzing samples containing pentachlorophenol.
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
