called hot, or in those which are said to be cold; in dry and in moist habits; in bilious and in phlegmatic subjects. Let us but examine impartially the observations, which have been transmitted to us upon this distemper, let us recollect the small-pox we have seen, whether natural or artificial, and we shall be obliged to confess that the constitutional dispositions, on which the mildness of the disorder depends, are to us entirely unknown, either because they have not been observed, or are beyond the power of observation.
Hence I think myself entitled to conclude, that there is no disposition, at least known to us, particularly relative to the small-pox, and enabling a subject to receive it in that manner, which is least detrimental; and consequently that there is no such thing as preparation for inoculation, in the sense we have affixed to that word.
But if we are ignorant of any particular disposition, we are certainly acquainted with a general one, which is absolutely requisite towards going through the small-pox with as little danger as possible; and that disposition is health itself. The venom applied, and the disorder consequent upon this application, are attacks upon health; and the hurt must be greater or less, as the constitution is weaker or stronger. Experience has shewn, that this disposition is always attended with a kind small-pox, provided other causes, or some error in the insertion or treatment of it do not increase the disorder, and disturb nature in her opera-
