- fore, is not purely a process of secretion but requires
some action on the part of the kidney, though no new substances are secreted in the kidney.
The passage of the urine down through the ureters is assisted by a kind of peristaltic action in the walls of the ureters and it is expelled from the body by the act of micturition, which is mostly voluntary, though a certain amount of nervous mechanism controls it. The seat of this nervous mechanism is in the lumbar enlargement of the spinal cord. In some nervous conditions, especially where there is injury to the spinal cord, there is involuntary micturition.
The urine is a watery solution containing many waste products, especially urea. It is generally amber in color, varying in shade with circumstances, with an aromatic, characteristic odor when fresh. It is acid in reaction and has a specific gravity of about 1020, though this too varies with circumstances. Besides water, which is its chief constituent, it contains urea, uric acid, organic acids, urates, inorganic salts, including sodium chloride and phosphates of calcium and magnesium, a certain amount of ammonia, and certain pigments. Its acidity is due to acid sodium phosphate in solution but varies with the food, and in disease the urine may become alkaline when passed. After standing a few hours in a warm place it decomposes and becomes alkaline.
The quantity, which is normally three pints or fifteen hundred cubic centimeters in twenty-four hours, varies with the amount of fluid drunk, the amount of perspiration, etc. The amount secreted depends chiefly, however, upon the flow of the blood through the kidneys; the greater the flow of blood, the larger the amount of urine formed; and the blood flow is determined by blood pressure and by vasomotor action. Secretion also seems to be increased by the presence of urea, which apparently serves as a stimulant to the kidney cells.
The excretion of waste materials takes place by three
