Inoculation into guinea-pigs invariably leads to a fatal result with the formation of nodules. If only a small dose is used, ½ to 1 minim of an 18 hours' broth culture, intraperitoneally, enlargement and inflammation of the testicle is got, as in Strauss' sign in glanders, in about 36 hours. With large doses death ensues too quickly. Guinea-pigs are also capable of infection by feeding with cultures.
A full account of the disease and its pathology can be found in an article by Major Whitmore in the Journal of Hygiene of April, 1913, to which I am indebted for what knowledge I have.
The specimens and the parent culture of these shewn was a present to the Bureau from Dr. L. G. Fink, of the Rangoon General Hospital.
