METHAMPHETAMINE . . . on Wipes by SPE: METHOD 9109, Issue 1, dated 17 October 2011 - Page 23 of 33
TABLE 11 (continued). Gas chromatographic retention times for heptafluorobutyryl and trimethylsilyl derivatives of selected drugs of abuse, precursors, and potential adulterants(1) GC Peak No.
Compound
Derivative Form(2)
41
Fentanyl (Sublimaze® etc.)
parent
42
Flunitrazepam (Rohypnol®, roofies)(10)
parent
43
Hydrocodone (Lortab® etc.)
HFB-
44
Hydrocodone (Lortab® etc.)
45 46
Notes (3)
Retention Time Minutes (4)
Relative Retention Time
Ions (Significant m/z) (7) 2’ (7)
3’ (7)
245
146 [60]
189 [33]
312
285 [95]
286 [90]
1.9588
495
438 [50]
298 [40]
1.6240
2.0946
371
356 [50]
234 [55]
20.93
1.6326
2.1056
299
242 [50]
243 [35]
19.85
1.5484
1.9970
308
267 [92]
358 [75]
Minor peak
20.98
1.6365
2.1107
414
429 [100]
234 [75]
O-TMS-
Pri.deriv.
21.21
1.6544
2.1338
357
300 [55]
342 [28]
parent
Major peak
15.24
1.1888
1.5332
180
182 [32]
209 [22]
Lidocaine
N-TMS-
Major peak
13.69
1.0679
1.3773
86
220 [75]
73 [45]
51
Lidocaine
parent
Major peak
15.28
1.1919
1.5372
86
58 [10]
91 [5]
52
LSD (MW-519, scanned only to 470)
HFB-
Pri.deriv.
24.61
1.9197
2.4759
417
221 [95]
418 [45]
53
MBDB
N-TMS-
Minor peak
14.30
1.1154
1.4386
144
73 [50]
135 [15]
54
MBDB
N-HFB-
Pri.deriv.
14.44
1.1264
1.4527
268
176 [75]
210 [50]
55
MDA
N-HFB-
Pri.deriv.
12.54
0.9782
1.2616
135
162 [55]
240 [12]
56
MDA
(5)
(6)
22.97
1.7917
2.3109
22.20
1.7317
2.2334
Minor peak
19.47
1.5187
TMS-
Minor peak
20.82
Hydrocodone (Lortab® etc.)
parent
Pri.deriv.
Hydromorphone (Dilaudid®)
O-HFB-O’-TMS-
Minor peak
47
Hydromorphone (Dilaudid®)
O,O’-bis-TMS-
48
Hydromorphone (Dilaudid®)
49
Ketamine (“special K”)(8)(10)
50
(8) (8)
1’
N-HFB-N-TMS-
OS artifact
12.88
1.0047
1.2958
312
73 [58]
135 [48]
57
(10)
MDEA
N-HFB-
Pri.deriv.
14.19
1.1069
1.4276
268
162 [60]
240 [50]
58
MDEA-D6 (I$)(9)
N-HFB-
Pri.deriv.
14.13
1.1022
1.4215
274
165 [46]
244 [35]
59
MDMA
N-HFB-
Pri.deriv.
13.81
1.0772
1.3893
254
162 [80]
135 [45]
60
Meperidine (Demerol® etc.)
parent
13.97
1.0897
1.4054
247
246 [55]
218 [50]
61
Mephentermine
N-HFB-
Pri.deriv.
10.38
0.8097
1.0443
268
210 [95]
62
Mescaline
N-HFB-
Pri.deriv.
14.68
1.1451
1.4769
181
194 [45]
63
Mescaline
N-HFB-N-TMS-
OS artifact
15.26
1.1903
1.5352
181
73 [35]
64
Methamphetamine
N-HFB-
Pri.deriv.
9.94
0.7754
1.0000
254
210 [35]
118 [22]
65
Methamphetamine-D5 (I$)(9)
N-HFB-
Pri.deriv.
9.86
0.7691
0.9920
258
213 [30]
92 [20]
66
(9)
Methamphetamine-D9 (I$)
N-HFB-
Pri.deriv.
9.84
0.7676
0.9899
261
213 [30]
123 [18]
67
(9)
Methamphetamine-D11 (I$)
N-HFB-
Pri.deriv.
9.84
0.7676
0.9899
260
213 [25]
126 [20]
68
Methamphetamine-D14 (I$)(9)
N-HFB-
Pri.deriv.
9.86
0.7691
0.9920
261
213 [30]
128 [20]
69
Methaqualone
parent
18.31
1.4282
1.8421
235
250 [30]
233 [28]
70
S-(-)-Methcathinone (“Cat”)
N-HFB-
Pri.deriv.
10.55
0.8229
1.0614
254
210 [35]
105 [100]
71
4-Methoxyamphetamine
N-HFB-
Pri.deriv.
11.40
0.8892
1.1469
121
148 [40]
240 [10]
72
4-Methoxyamphetamine
N-HFB-N-TMS-
OS artifact
11.87
0.9259
1.1942
312
121 [100]
73 [100]
73
cis-(±)-4-Methylaminorex (“U4Euh”)
N,N’-bis-HFB-
Minor peak
13.78
1.0749
1.3863
399
169 [70]
160 [75]
74
cis-(±)-4-Methylaminorex (“U4Euh”)
N-HFB-N’-TMS-
Pri.deriv.
16.78
1.3089
1.6881
275
160 [60]
117 [30]
75
(-)-N-Methylephedrine
O-TMS-
Pri.deriv.
9.66
0.7535
0.9718
72
73 [13]
163 [5]
76
(+)-N-Methylephedrine
O-TMS-
Pri.deriv.
9.71
0.7574
0.9769
72
73 [13]
163 [5]
77
N-Methylphenethylamine (I$)
N-HFB-
Pri.deriv.
9.54
0.7441
0.9598
240
104 [100]
169 [40]
78
Methylphenidate (Ritalin®)
N-HFB-
Pri.deriv.
15.38
1.1997
1.5473
280
281 [10]
(10)
(12) (12) (9)
179 [30]
Table 11 continued
NIOSH Manual of Analytical Methods (NMAM), Fifth Edition
Method rev. 1.1.1
