Zoonomia/I.XXXIV

by Erasmus Darwin

SECT. XXXIV.

DISEASES OF VOLITION.

I. 1. Volition defined. Motions termed involuntary are caused by volition. Desires opposed to each other. Deliberation. Ass between two hay-cocks. Saliva swallowed against one's desire. Voluntary motions distinguished from those associated with sensitive motions. 2. Pains from excess, and from defect of motion. No pain is felt during vehement voluntary exertion; as in cold fits of ague, labour-pains, strangury, tenesmus, vomiting, restlessness in fevers, convulsion of a wounded muscle. 3. Of holding the breath and screaming in pain; why swine and dogs cry out in pain, and not sheep and horses. Of grinning and biting in pain; why mad animals bite others. 4. Epileptic convulsions explained, why the fits begin with quivering of the under jaw, biting the tongue, and setting the teeth; why the convulsive motions are alternately relaxed. The phenomenon of laughter explained. Why children cannot tickle themselves. How some have died from immoderate laughter. 5. Of cataleptic spasms, of the locked jaw, of painful cramps. 6. Syncope explained. Why no external objects are perceived in syncope. 7. Of palsy and apoplexy from violent exertions. Case of Mrs. Scot. From dancing, scating, swimming. Case of Mr. Nairn. Why palsies are not always immediately preceded by violent exertions. Palsy and epilepsy from diseased livers. Why the right arm more frequently paralytic than the left. How paralytic limbs regain their motions. II. Diseases of the sensual motions from excess or defect of voluntary exertion. 1. Madness. 2. Distinguished from delirium. 3. Why mankind more liable to insanity than brutes. 4. Suspicion. Want of shame, and of cleanliness. 5. They bear cold, hunger, and fatigue. Charles XII. of Sweden. 6. Pleasureable delirium, and insanity. Child riding on a stick. Pains of martyrdom not felt. 7. Dropsy. 8. Inflammation cured by insanity. III. 1. Pain relieved by reverie. Reverie is an exertion of voluntary and sensitive motions. 2. Case of reverie. 3. Lady supposed to have two souls. 4. Methods of relieving pain.

I. 1. Before we commence this Section on Diseased Voluntary Motions, it may be necessary to premise, that the word volition is not used in this work exactly in its common acceptation. Volition is said in Section V. to bear the same analogy to desire and aversion, which sensation does to pleasure and pain. And hence that, when desire or aversion produces any action of the muscular fibres, or of the organs of sense, they are termed volition; and the actions produced in consequence are termed voluntary actions. Whence it appears, that motions of our muscles or ideas may be produced in consequence of desire or aversion without our having the power to prevent them, and yet these motions may be termed voluntary, according to our definition of the word; though in common language they would be called involuntary.

The objects of desire and aversion are generally at a distance, whereas those of pleasure and pain are immediately acting upon our organs. Hence, before desire or aversion are exerted, so as to cause any actions, there is generally time for deliberation; which consists in discovering the means to obtain the object of desire, or to avoid the object of aversion; or in examining the good or bad consequences, which may result from them. In this case it is evident, that we have a power to delay the proposed action, or to perform it; and this power of choosing, whether we shall act or not, is in common language expressed by the word volition, or will. Whereas in this work the word volition means simply the active state of the sensorial faculty in producing motion in consequence of desire or aversion: whether we have the power of restraining that action, or not; that is, whether we exert any actions in consequence of opposite desires or aversions, or not.

For if the objects of desire or aversion are present, there is no necessity to investigate or compare the means of obtaining them, nor do we always deliberate about their consequences; that is, no deliberation necessarily intervenes, and in consequence the power of choosing to act or not is not exerted. It is probable, that this twofold use of the word volition in all languages has confounded the metaphysicians, who have disputed about free will and necessity. Whereas from the above analysis it would appear, that during our sleep, we use no voluntary exertions at all; and in our waking hours, that they are the consequence of desire or aversion.

To will is to act in consequence of desire; but to desire means to desire something, even if that something be only to become free from the pain, which causes the desire; for to desire nothing is not to desire; the word desire, therefore, includes both the action and the object or motive; for the object and motive of desire are the same thing. Hence to desire without an object, that is, without a motive, is a solecism in language. As if one should ask, if you could eat without food, or breathe without air.

From this account of volition it appears, that convulsions of the muscles, as in epileptic fits, may in the common sense of that word be termed involuntary; because no deliberation is interposed between the desire or aversion and the consequent action; but in the sense of the word, as above defined, they belong to the class of voluntary motions, as delivered in Vol. II. Class III. If this use of the word be discordant to the ear of the reader, the term morbid voluntary motions, or motions in consequence of aversion, may be substituted in its stead.

If a person has a desire to be cured of the ague, and has at the same time an aversion (or contrary desire) to swallowing an ounce of Peruvian bark; he balances desire against desire, or aversion against aversion; and thus he acquires the power of choosing, which is the common acceptation of the word willing. But in the cold fit of ague, after having discovered that the act of shuddering, or exerting the subcutaneous muscles, relieves the pain of cold; he immediately exerts this act of volition, and shudders, as soon as the pain and consequent aversion return, without any deliberation intervening; yet is this act, as well as that of swallowing an ounce of the bark, caused by volition; and that even though he endeavours in vain to prevent it by a weaker contrary volition. This recalls to our minds the story of the hungry ass between two hay-stacks, where the two desires are supposed so exactly to counteract each other, that he goes to neither of the stacks, but perishes by want. Now as two equal and opposite desires are thus supposed to balance each other, and prevent all action, it follows, that if one of these hay-stacks was suddenly removed, that the ass would irresistibly be hurried to the other, which in the common use of the word might be called an involuntary act; but which, in our acceptation of it, would be classed amongst voluntary actions, as above explained.

Hence to deliberate is to compare opposing desires or aversions, and that which is the most interesting at length prevails, and produces action. Similar to this, where two pains oppose each other, the stronger or more interesting one produces action; as in pleurisy the pain from suffocation would produce expansion of the lungs, but the pain occasioned by extending the inflamed membrane, which lines the chest, opposes this expansion, and one or the other alternately prevails.

When any one moves his hand quickly near another person's eyes, the eye-lids instantly close; this act in common language is termed involuntary, as we have not time to deliberate or to exert any contrary desire or aversion, but in this work it would be termed a voluntary act, because it is caused by the faculty of volition, and after a few trials the nictitation can be prevented by a contrary or opposing volition.

The power of opposing volitions is best exemplified in the story of Mutius Scævola, who is said to have thrust his hand into the fire before Porcenna, and to have suffered it to be consumed for having failed him in his attempt on the life of that general. Here the aversion for the loss of same, or the unsatisfied desire to serve his country, the two prevalent enthusiasms at that time, were more powerful than the desire of withdrawing his hand, which must be occasioned by the pain of combustion; of these opposing volitions

Vincit amor patriæ, laudumque immensa cupido.

If any one is told not to swallow his saliva for a minute, he soon swallows it contrary to his will, in the common sense of that word; but this also is a voluntary action, as it is performed by the faculty of volition, and is thus to be understood. When the power of volition is exerted on any of our senses, they become more acute, as in our attempts to hear small noises in the night. As explained in Section XIX. 6. Hence by our attention to the fauces from our desire not to swallow our saliva; the fauces become more sensible; and the stimulus of the saliva is followed by greater sensation, and consequent desire of swallowing it. So that the desire or volition in consequence of the increased sensation of the saliva is more powerful, than the previous desire not to swallow it. See Vol. II. Deglutitio invita. In the same manner if a modest man wishes not to want to make water, when he is confined with ladies in a coach or an assembly-room; that very act of volition induces the circumstance, which he wishes to avoid, as above explained; insomuch that I once saw a partial insanity, which might be called a voluntary diabetes, which was occasioned by the fear (and consequent aversion) of not being able to make water at all.

It is further necessary to observe here, to prevent any confusion of voluntary, with sensitive, or associate motions, that in all the instances of violent efforts to relieve pain, those efforts are at first voluntary exertions; but after they have been frequently repeated for the purpose of relieving certain pains, they become associated with those pains, and cease at those times to be subservient to the will; as in coughing, sneezing, and strangury. Of these motions those which contribute to remove or dislodge the offending cause, as the actions of the abdominal muscles in parturition or in vomiting, though they were originally excited by volition, are in this work termed sensitive motions; but those actions of the muscles or organs of sense, which do not contribute to remove the offending cause, as in general convulsions or in madness, are in this work termed voluntary motions, or motions in consequence of aversion, though in common language they are called involuntary ones. Those sensitive unrestrainable actions, which contribute to remove the cause of pain are uniformly and invariably exerted, as in coughing or sneezing; but those motions which are exerted in consequence of aversion without contributing to remove the painful cause, but only to prevent the sensation of it, as in epileptic, or cataleptic fits, are not uniformly and invariably exerted, but change from one set of muscles to another, as will be further explained; and may by this criterion also be distinguished from the former.

At the same time those motions, which are excited by perpetual stimulus, or by association with each other, or immediately by pleasureable or painful sensation, may properly be termed involuntary motions, as those of the heart and arteries; as the faculty of volition seldom affects those, except when it exists in unnatural quantity, as in maniacal people.

2. It was observed in Section XIV. on the Production of Ideas, that those parts of the system, which are usually termed the organs of sense, are liable to be excited into pain by the excess of the stimulus of those objects, which are by nature adapted to affect them; as of too great light, sound, or pressure. But that these organs receive no pain from the defect or absence of these stimuli, as in darkness or silence. But that our other organs of perception, which have generally been called appetites, as of hunger, thirst, want of heat, want of fresh air, are liable to be affected with pain by the defect, as well as by the excess of their appropriated stimuli.

This excess or defect of stimulus is however to be considered only as the remote cause of the pain, the immediate cause being the excess or defect of the natural action of the affected part, according to Sect. IV. 5. Hence all the pains of the body may be divided into those from excess of motion, and those from defect of motion; which distinction is of great importance in the knowledge and the cure of many diseases. For as the pains from excess of motion either gradually subside, or are in general succeeded by inflammation; so those from defect of motion either gradually subside, or are in general succeeded by convulsion, or madness. These pains are easily distinguishable from each other by this circumstance, that the former are attended with heat of the pained part, or of the whole body; whereas the latter exists without increase of heat in the pained part, and is generally attended with coldness of the extremities of the body; which is the true criterion of what have been called nervous pains.

Thus when any acrid material, as snuff or lime, falls into the eye, pain and inflammation and heat are produced from the excess of stimulus; but violent hunger, hemicrania, or the clavus hystericus, are attended with coldness of the extremities, and defect of circulation. When we are exposed to great cold, the pain we experience from the deficiency of heat is attended with a quiescence of the motions of the vascular system; so that no inflammation is produced, but a great desire of heat, and a tremulous motion of the subcutaneous muscles, which is properly a convulsion in consequence of this pain from defect of the stimulus of heat.

It was before mentioned, that as sensation consists in certain movements of the sensorium, beginning at some of the extremities of it, and propagated to the central parts of it; so volition consists of certain other movements of the sensorium, commencing in the central parts of it, and propagated to some of its extremities. This idea of these two great powers of motion in the animal machine is confirmed from observing, that they never exist in a great degree or universally at the same time; for while we strongly exert our voluntary motions, we cease to feel the pains or uneasinesses, which occasioned us to exert them.

Hence during the time of fighting with fists or swords no pain is felt by the combatants, till they cease to exert themselves. Thus in the beginning of ague-fits the painful sensation of cold is diminished, while the patient exerts himself in the shivering and gnashing of his teeth. He then ceases to exert himself, and the pain of cold returns; and he is thus perpetually induced to reiterate these exertions, from which he experiences a temporary relief. The same occurs in labour-pains, the exertion of the parturient woman relieves the violence of the pains for a time, which recur again soon after she has ceased to use those exertions. The same is true in many other painful diseases, as in the strangury, tenesmus, and the efforts of vomiting; all these disagreeable sensations are diminished or removed for a time by the various exertions they occasion, and recur alternately with those exertions.

The restlessness in some fevers is an almost perpetual exertion of this kind, excited to relieve some disagreeable sensations; the reciprocal opposite exertions of a wounded worm, the alternate emprosthotonos and opisthotonos of some spasmodic diseases, and the intervals of all convulsions, from whatever cause, seem to be owing to this circumstance of the laws of animation; that great or universal exertion cannot exist at the same time with great or universal sensation, though they can exist reciprocally; which is probably resolvable into the more general law, that the whole sensorial power being expended in one mode of exertion, there is none to spare for any other. Whence syncope, or temporary apoplexy, succeeds to epileptic convulsions.

3. Hence when any violent pain afflicts us, of which we can neither avoid nor remove the cause, we soon learn to endeavour to alleviate it, by exerting some violent voluntary effort, as mentioned above; and are naturally induced to use those muscles for this purpose, which have been in the early periods of our lives most frequently or most powerfully exerted.

Now the first muscles, which infants use most frequently, are those of respiration; and on this account we gain a habit of holding our breath, at the same time that we use great efforts to exclude it, for this purpose of alleviating unavoidable pain; or we press out our breath through a small aperture of the larynx, and scream violently, when the pain is greater than is relievable by the former mode of exertion. Thus children scream to relieve any pain either of body or mind, as from anger, or fear of being beaten.

Hence it is curious to observe, that those animals, who have more frequently exerted their muscles of respiration violently, as in talking, barking, or grunting, as children, dogs, hogs, scream much more, when they are in pain, than those other animals, who use little or no language in their common modes of life; as horses, sheep, and cows.

The next most frequent or most powerful efforts, which infants are first tempted to produce, are those with the muscles in biting hard substances; indeed the exertion of these muscles is very powerful in common mastication, as appears from the pain we receive, if a bit of bone is unexpectedly found amongst our softer food; and further appears from their acting to so great mechanical disadvantage, particularly when we bite with the incisores, or canine teeth; which are first formed, and thence are first used to violent exertion.

Hence when a person is in great pain, the cause of which he cannot remove, he sets his teeth firmly together, or bites some substance between them with great vehemence, as another mode of violent exertion to produce a temporary relief. Thus we have a proverb where no help can be had in pain, "to grin and abide;" and the tortures of hell are said to be attended with "gnashing of teeth."

Hence in violent spasmodic pains I have seen people bite not only their tongues, but their arms or fingers, or those of the attendants, or any object which was near them; and also strike, pinch, or tear, others or themselves, particularly the part of their own body, which is painful at the time. Soldiers, who die of painful wounds in battle, are said in Homer to bite the ground. Thus also in the bellon, or colica saturnina, the patients are said to bite their own flesh, and dogs in this disease to bite up the ground they lie upon. It is probable that the great endeavours to bite in mad dogs, and the violence of other mad animals, is owing to the same cause.

4. If the efforts of our voluntary motions are exerted with still greater energy for the relief of some disagreeable sensation, convulsions are produced; as the various kinds of epilepsy, and in some hysteric paroxysms. In all these diseases a pain, or disagreeable sensation is produced, frequently by worms, or acidity in the bowels, or by a diseased nerve in the side, or head, or by the pain of a diseased liver.

In some constitutions a more intolerable degree of pain is produced in some part at a distance from the cause by sensitive association, as before explained; these pains in such constitutions arise to so great a degree, that I verily believe no artificial tortures could equal some, which I have witnessed; and am confident life would not have long been preserved, unless they had been soon diminished or removed by the universal convulsion of the voluntary motions, or by temporary madness.

In some of the unfortunate patients I have observed, the pain has risen to an inexpressible degree, as above described, before the convulsions have supervened; and which were preceded by screaming, and grinning; in others, as in the common epilepsy, the convulsion has immediately succeeded the commencement of the disagreeable sensations; and as a stupor frequently succeeds the convulsions, they only seemed to remember that a pain at the stomach preceded the fit, or some other uneasy feel; or more frequently retained no memory at all of the immediate cause of the paroxysm. But even in this kind of epilepsy, where the patient does not recollect any preceding pain, the paroxysms generally are preceded by a quivering motion of the under jaw, with a biting of the tongue; the teeth afterwards become pressed together with vehemence, and the eyes are then convulsed, before the commencement of the universal convulsion; which are all efforts to relieve pain.

The reason why these convulsive motions are alternately exerted and remitted was mentioned above, and in Sect. XII. 1. 3. when the exertions are such as give a temporary relief to the pain, which excites them, they cease for a time, till the pain is again perceived; and then new exertions are produced for its relief. We see daily examples of this in the loud reiterated laughter of some people; the pleasureable sensation, which excites this laughter, arises for a time so high as to change its name and become painful: the convulsive motions of the respiratory muscles relieve the pain for a time; we are, however, unwilling to lose the pleasure, and presently put a stop to this exertion, and immediately the pleasure recurs, and again as instantly rises into pain. All of us have felt the pain of immoderate laughter; children have been tickled into convulsions of the whole body; and others have died in the act of laughing; probably from a paralysis succeeding the long continued actions of the muscles of respiration.

Hence we learn the reason, why children, who are so easily excited to laugh by the tickling of other people's fingers, cannot tickle themselves into laughter. The exertion of their hands in the endeavour to tickle themselves prevents the necessity of any exertion of the respiratory muscles to relieve the excess of pleasurable affection. See Sect. XVII. 3. 5.

Chrysippus is recorded to have died laughing, when an ass was invited to sup with him. The same is related of one of the popes, who, when he was ill, saw a tame monkey at his bedside put on the holy thiara. Hall. Phys. T. III. p. 306.

There are instances of epilepsy being produced by laughing recorded by Van Swieten, T. III. 402 and 308. And it is well known, that many people have died instantaneously from the painful excess of joy, which probably might have been prevented by the exertions of laughter.

Every combination of ideas, which we attend to, occasions pain or pleasure; those which occasion pleasure, furnish either social or selfish pleasure, either malicious or friendly, or lascivious, or sublime pleasure; that is, they give us pleasure mixed with other emotions, or they give us unmixed pleasure, without occasioning any other emotions or exertions at the same time. This unmixed pleasure, if it be great, becomes painful, like all other animal motions from stimuli of every kind; and if no other exertions are occasioned at the same time, we use the exertion of laughter to relieve this pain. Hence laughter is occasioned by such wit as excites simple pleasure without any other emotion, such as pity, love, reverence. For sublime ideas are mixed with admiration, beautiful ones with love, new ones with surprise; and these exertions of our ideas prevent the action of laughter from being necessary to relieve the painful pleasure above described. Whence laughable wit consists of frivolous ideas, without connections of any consequence, such as puns on words, or on phrases, incongruous junctions of ideas; on which account laughter is so frequent in children.

Unmixed pleasure less than that, which causes laughter, causes sleep, as in singing children to sleep, or in slight intoxication from wine or food. See Sect. XVIII. 12.

5. If the pains, or disagreeable sensations, above described do not obtain a temporary relief from these convulsive exertions of the muscles, those convulsive exertions continue without remission, and one kind of catalepsy is produced. Thus when a nerve or tendon produces great pain by its being inflamed or wounded, the patient sets his teeth firmly together, and grins violently, to diminish the pain; and if the pain is not relieved by this exertion, no relaxation of the maxillary muscles takes place, as in the convulsions above described, but the jaws remain firmly fixed together. This locked jaw is the most frequent instance of cataleptic spasm, because we are more inclined to exert the muscles subservient to mastication from their early obedience to violent efforts of volition.

But in the case related in Sect. XIX. on Reverie, the cataleptic lady had pain in her upper teeth; and pressing one of her hands vehemently against her cheek-bone to diminish this pain, it remained in that attitude for about half an hour twice a day, till the painful paroxysm was over.

I have this very day seen a young lady in this disease, (with which she has frequently been afflicted,) she began to-day with violent pain shooting from one side of the forehead to the occiput, and after various struggles lay on the bed with her fingers and wrists bent and stiff for about two hours; in other respects she seemed in a syncope with a natural pulse. She then had intervals of pain and of spasm, and took three grains of opium every hour till she had taken nine grains, before the pains and spasm ceased.

There is, however, another species of fixed spasm, which differs from the former, as the pain exists in the contracted muscle, and would seem rather to be the consequence than the cause of the contraction, as in the cramp in the calf of the leg, and in many other parts of the body.

In these spasms it should seem, that the muscle itself is first thrown into contraction by some disagreeable sensation, as of cold; and that then the violent pain is produced by the great contraction of the muscular fibres extending its own tendons, which are said to be sensible to extension only; and is further explained in Sect. XVIII. 15.

6. Many instances have been given in this work, where after violent motions excited by irritation, the organ has become quiescent to less, and even to the great irritation, which induced it into violent motion; as after looking long at the sun or any bright colour, they cease to be seen; and after removing from bright day-light into a gloomy room, the eye cannot at first perceive the objects, which stimulate it less. Similar to this is the syncope, which succeeds after the violent exertions of our voluntary motions, as after epileptic fits, for the power of volition acts in this case as the stimulus in the other. This syncope is a temporary palsy, or apoplexy, which ceases after a time, the muscles recovering their power of being excited into action by the efforts of volition; as the eye in the circumstance above mentioned recovers in a little time its power of seeing objects in a gloomy room; which were invisible immediately after coming out of a stronger light. This is owing to an accumulation of sensorial power during the inaction of those fibres, which were before accustomed to perpetual exertions, as explained in Sect. XII. 7. 1. A slighter degree of this disease is experienced by every one after great fatigue, when the muscles gain such inability to further action, that we are obliged to rest them for a while, or to summon a greater power of volition to continue their motions.

In all the syncopes, which I have seen induced after convulsive fits, the pulse has continued natural, though the organs of sense, as well as the locomotive muscles, have ceased to perform their functions; for it is necessary for the perception of objects, that the external organs of sense should be properly excited by the voluntary power, as the eye-lids must be open, and perhaps the muscles of the eye put into action to distend, and thence give greater pellucidity to the cornea, which in syncope, as in death, appears flat and less transparent.

The tympanum of the ear also seems to require a voluntary exertion of its muscles, to gain its due tension, and it is probable the other external organs of sense require a similar voluntary exertion to adapt them to the distinct perception of objects. Hence in syncope as in sleep, as the power of volition is suspended, no external objects are perceived. See Sect. XVIII. 5. During the time which the patient lies in a fainting fit, the spirit of animation becomes accumulated; and hence the muscles in a while become irritable by their usual stimulation, and the fainting fit ceases. See Sect. XII. 7. 1.

7. If the exertion of the voluntary motions has been still more energetic, the quiescence, which succeeds, is so complete, that they cannot again be excited into action by the efforts of the will. In this manner the palsy, and apoplexy (which is an universal palsy) are frequently produced after convulsions, or other violent exertions; of this I shall add a few instances.

Platernus mentions some, who have died apoplectic from violent exertions in dancing; and Dr. Mead, in his Essay on Poisons, records a patient in the hydrophobia, who at one effort broke the cords which bound him, and at the same instant expired. And it is probable, that those, who have expired from immoderate laughter, have died from this paralysis consequent to violent exertion. Mrs. Scott of Stafford was walking in her garden in perfect health with her neighbour Mrs. ——; the latter accidentally fell into a muddy rivulet, and tried in vain to disengage herself by the assistance of Mrs. Scott's hand. Mrs. Scott exerted her utmost power for many minutes, first to assist her friend, and next to prevent herself from being pulled into the morass, as her distressed companion would not disengage her hand. After other assistance was procured by their united screams, Mrs. Scott walked to a chair about twenty yards from the brook, and was seized with an apoplectic stroke: which continued many days, and terminated in a total loss of her right arm, and her speech; neither of which she ever after perfectly recovered.

It is said, that many people in Holland have died after skating too long or too violently on their frozen canals; it is probable the death of these, and of others, who have died suddenly in swimming, has been owing to this great quiescence or paralysis; which has succeeded very violent exertions, added to the concomitant cold, which has had greater effect after the sufferers had been heated and exhausted by previous exercise.

I remember a young man of the name of Nairne at Cambridge, who walking on the edge of a barge fell into the river. His cousin and fellow-student of the same name, knowing the other could not swim, plunged into the water after him, caught him by his clothes, and approaching the bank by a vehement exertion propelled him safe to the land, but that instant, seized, as was supposed, by the cramp, or paralysis, sunk to rise no more. The reason why the cramp of the muscles, which compose the calf of the leg, is so liable to affect swimmers, is, because these muscles have very weak antagonists, and are in walking generally elongated again after their contraction by the weight of the body on the ball of the toe, which is very much greater than the resistance of the water in swimming. See Section XVIII. 15.

It does not follow that every apoplectic or paralytic attack is immediately preceded by vehement exertion; the quiescence, which succeeds exertion, and which is not so great as to be termed paralysis, frequently recurs afterwards at certain periods; and by other causes of quiescence, occurring with those periods, as was explained in treating of the paroxysms of intermitting fevers; the quiescence at length, becomes so great as to be incapable of again being removed by the efforts of volition, and complete paralysis is formed. See Section XXXII. 3. 2.

Many of the paralytic patients, whom I have seen, have evidently had diseased livers from the too frequent potation of spirituous liquors; some of them have had the gutta rosea on their faces and breasts; which has in some degree receded either spontaneously, or by the use of external remedies, and the paralytic stroke has succeeded; and as in several persons, who have drank much vinous spirits, I have observed epileptic fits to commence at about forty or fifty years of age, without any hereditary taint, from the stimulus, as I believed, of a diseased liver; I was induced to ascribe many paralytic cases to the same source; which were not evidently the effect of age, or of unacquired debility. And the account given before of dropsies, which very frequently are owing to a paralysis of the absorbent system, and are generally attendant on free drinkers of spirituous liquors, confirmed me in this opinion.

The disagreeable irritation of a diseased liver produces exertions and consequent quiescence; these by the accidental concurrence of other causes of quiescence, as cold, solar or lunar periods, inanition, the want of their usual portion of spirit of wine, at length produces paralysis.

This is further confirmed by observing, that the muscles, we most frequently, or most powerfully exert, are most liable to palsy; as those of the voice and of articulation, and of those paralytics which I have seen, a much greater proportion have lost the use of their right arm; which is so much more generally exerted than the left.

I cannot dismiss this subject without observing, that after a paralytic stroke, if the vital powers are not much injured, that the patient has all the movements of the affected limb to learn over again, just as in early infancy; the limb is first moved by the irritation of its muscles, as in stretching, (of which a case was related in Section VII. 1. 3.) or by the electric concussion; afterwards it becomes obedient to sensation, as in violent danger or fear; and lastly, the muscles become again associated with volition, and gradually acquire their usual habits of acting together.

Another phænomenon in palsies is, that when the limbs of one side are disabled, those of the other are in perpetual motion. This can only be explained from conceiving that the power of motion, whatever it is, or wherever it resides, and which is capable of being exhausted by fatigue, and accumulated in rest, is now less expended, whilst one half of the body is capable of receiving its usual proportion of it, and is hence derived with greater ease or in greater abundance into the limbs, which remain unaffected.

II. 1. The excess or defect of voluntary exertion produces similar effects upon the sensual motions, or ideas of the mind, as those already mentioned upon the muscular fibres. Thus when any violent pain, arising from the defect of some peculiar stimulus, exists either in the muscular or sensual systems of fibres, and which cannot be removed by acquiring the defective stimulus; as in some constitutions convulsions of the muscles are produced to procure a temporary relief, so in other constitutions vehement voluntary exertions of the ideas of the mind are produced for the same purpose; for during this exertion, like that of the muscles, the pain either vanishes or is diminished: this violent exertion constitutes madness; and in many cases I have seen the madness take place, and the convulsions cease, and reciprocally the madness cease, and the convulsions supervene. See Section III. 5. 8.

2. Madness is distinguishable from delirium, as in the latter the patient knows not the place where he resides, nor the persons of his friends or attendants, nor is conscious of any external objects, except when spoken to with a louder voice, or stimulated with unusual force, and even then he soon relapses into a state of inattention to every thing about him. Whilst in the former he is perfectly sensible to every thing external, but has the voluntary powers of his mind intensely exerted on some particular object of his desire or aversion, he harbours in his thoughts a suspicion of all mankind, lest they should counteract his designs; and while he keeps his intentions, and the motives of his actions profoundly secret; he is perpetually studying the means of acquiring the object of his wish, or of preventing or revenging the injuries he suspects.

3. A late French philosopher, Mr. Helvetius, has deduced almost all our actions from this principle of their relieving us from the ennui or tædium vitæ; and true it is, that our desires or aversions are the motives of all our voluntary actions; and human nature seems to excel other animals in the more facil use of this voluntary power, and on that account is more liable to insanity than other animals. But in mania this violent exertion of volition is expended on mistaken objects, and would not be relieved, though we were to gain or escape the objects, that excite it. Thus I have seen two instances of madmen, who conceived that they had the itch, and several have believed they had the venereal infection, without in reality having a symptom of either of them. They have been perpetually thinking upon this subject, and some of them were in vain salivated with design of convincing them to the contrary.

4. In the minds of mad people those volitions alone exist, which are unmixed with sensation; immoderate suspicion is generally the first symptom, and want of shame, and want of delicacy about cleanliness. Suspicion is a voluntary exertion of the mind arising from the pain of fear, which it is exerted to relieve: shame is the name of a peculiar disagreeable sensation, see Fable of the Bees, and delicacy about cleanliness arises from another disagreeable sensation. And therefore are not found in the minds of maniacs, which are employed solely in voluntary exertions. Hence the most modest women in this disease walk naked amongst men without any kind of concern, use obscene discourse, and have no delicacy about their natural evacuations.

5. Nor are maniacal people more attentive to their natural appetites, or to the irritations which surround them, except as far as may respect their suspicions or designs; for the violent and perpetual exertions of their voluntary powers of mind prevents their perception of almost every other object, either of irritation or of sensation. Hence it is that they bear cold, hunger, and fatigue, with much greater pertinacity than in their sober hours, and are less injured by them in respect to their general health. Thus it is asserted by historians, that Charles the Twelfth of Sweden slept on the snow, wrapped only in his cloak, at the siege of Frederickstad, and bore extremes of cold and hunger, and fatigue, under which numbers of his soldiers perished; because the king was insane with ambition, but the soldier had no such powerful stimulus to preserve his system from debility and death.

6. Besides the insanities arising from exertions in consequence of pain, there is also a pleasurable insanity, as well as a pleasurable delirium; as the insanity of personal vanity, and that of religious fanaticism. When agreeable ideas excite into motion the sensorial power of sensation, and this again causes other trains of agreeable ideas, a constant stream of pleasurable ideas succeeds, and produces pleasurable delirium. So when the sensorial power of volition excites agreeable ideas, and the pleasure thus produced excites more volition in its turn, a constant flow of agreeable voluntary ideas succeeds; which when thus exerted in the extreme constitutes insanity.

Thus when our muscular actions are excited by our sensations of pleasure, it is termed play; when they are excited by our volition, it is termed work; and the former of these is attended with less fatigue, because the muscular actions in play produce in their turn more pleasurable sensation; which again has the property of producing more muscular action. An agreeable instance of this I saw this morning. A little boy, who was tired with walking, begged of his papa to carry him. "Here," says the reverend doctor, "ride upon my gold-headed cane;" and the pleased child, putting it between his legs, gallopped away with delight, and complained no more of his fatigue. Here the aid of another sensorial power, that of pleasurable sensation, superadded vigour to the exertion of exhausted volition. Which could otherwise only have been excited by additional pain, as by the lash of slavery. On this account where the whole sensorial power has been exerted on the contemplation of the promised joys of heaven, the saints of all persecuted religions have borne the tortures of martyrdom with otherwise unaccountable firmness.

7. There are some diseases, which obtain at least a temporary relief from the exertions of insanity; many instances of dropsies being thus for a time cured are recorded. An elderly woman labouring with ascites I twice saw relieved for some weeks by insanity, the dropsy ceased for several weeks, and recurred again alternating with the insanity. A man afflicted with difficult respiration on lying down, with very irregular pulse, and œdematous legs, whom I saw this day, has for above a week been much relieved in respect to all those symptoms by the accession of insanity, which is shewn by inordinate suspicion, and great anger.

In cases of common temporary anger the increased action of the arterial system is seen by the red skin, and increased pulse, with the immediate increase of muscular activity. A friend of mine, when he was painfully fatigued by riding on horseback, was accustomed to call up ideas into his mind, which used to excite his anger or indignation, and thus for a time at least relieved the pain of fatigue. By this temporary insanity, the effect of the voluntary power upon the whole of his system was increased; as in the cases of dropsy above mentioned, it would appear, that the increased action of the voluntary faculty of the sensorium affected the absorbent system, as well as the secerning one.

8. In respect to relieving inflammatory pains, and removing fever, I have seen many instances, as mentioned in Sect. XII. 2. 4. One lady, whom I attended, had twice at some years interval a locked jaw, which relieved a pain on her sternum with peripneumony. Two other ladies I saw, who towards the end of violent peripneumony, in which they frequently lost blood, were at length cured by insanity supervening. In the former the increased voluntary exertion of the muscles of the jaw, in the latter that of the organs of sense, removed the disease; that is, the disagreeable sensation, which had produced the inflammation, now excited the voluntary power, and these new voluntary exertions employed or expended the superabundant sensorial power, which had previously been exerted on the arterial system, and caused inflammation.

Another case, which I think worth relating, was of a young man about twenty; he had laboured under an irritative fever with debility for three or four weeks, with very quick and very feeble pulse, and other usual symptoms of that species of typhus, but at this time complained much and frequently of pain of his legs and feet. When those who attended him were nearly in despair of his recovery, I observed with pleasure an insanity of mind supervene: which was totally different from delirium, as he knew his friends, calling them by their names, and the room in which he lay, but became violently suspicious of his attendants, and calumniated with vehement oaths his tender mother, who sat weeping by his bed. On this his pulse became slower and firmer, but the quickness did not for some time intirely cease, and he gradually recovered. In this case the introduction of an increased quantity of the power of volition gave vigour to those movements of the system, which are generally only actuated by the power of irritation, and of association.

Another case I recollect of a young man, about twenty-five, who had the scarlet-fever, with very quick pulse, and an universal eruption on his skin, and was not without reason esteemed to be in great danger of his life. After a few days an insanity supervened, which his friends mistook for delirium, and he gradually recovered, and the cuticle peeled off. From these and a few other cases I have always esteemed insanity to be a favourable sign in fevers, and have cautiously distinguished it from delirium.

III. Another mode of mental exertion to relieve pain, is by producing a train of ideas not only by the efforts of volition, as in insanity; but by those of sensation likewise, as in delirium and sleep. This mental effort is termed reverie, or somnambulation, and is described more at large in Sect. XIX. on that subject. But I shall here relate another case of that wonderful disease, which fell yesterday under my eye, and to which I have seen many analogous alienations of mind, though not exactly similar in all circumstances. But as all of them either began or terminated with pain or convulsion, there can be no doubt but that they are of epileptic origin, and constitute another mode of mental exertion to relieve some painful sensation.

1. Master A. about nine years old, had been seized at seven every morning for ten days with uncommon fits, and had had slight returns in the afternoon. They were supposed to originate from worms, and had been in vain attempted to be removed by vermifuge purges. As his fit was expected at seven yesterday morning, I saw him before that hour; he was asleep, seemed free from pain, and his pulse natural. About seven he began to complain of pain about his navel, or more to the left side, and in a few minutes had exertions of his arms and legs like swimming. He then for half an hour hunted a pack of hounds; as appeared by his hallooing, and calling the dogs by their names, and discoursing with the attendants of the chase, describing exactly a day of hunting, which (I was informed) he had witnessed a year before, going through all the most minute circumstances of it; calling to people, who were then present, and lamenting the absence of others, who were then also absent. After this scene he imitated, as he lay in bed, some of the plays of boys, as swimming and jumping. He then sung an English and then an Italian song; part of which with his eyes open, and part with them closed, but could not be awakened or excited by any violence, which it was proper to use.

After about an hour he came suddenly to himself with apparent surprise, and seemed quite ignorant of any part of what had passed, and after being apparently well for half an hour, he suddenly fell into a great stupor, with slower pulse than natural, and a slow moaning respiration, in which he continued about another half hour, and then recovered.

The sequel of this disease was favourable; he was directed one grain of opium at six every morning, and then to rise out of bed; at half past six he was directed fifteen drops of laudanum in a glass of wine and water. The first day the paroxysm became shorter, and less violent. The dose of opium was increased to one-half more, and in three or four days the fits left him. The bark and filings of iron were also exhibited twice a day; and I believe the complaint returned no more.

2. In this paroxysm it must be observed, that he began with pain, and ended with stupor, in both circumstances resembling a fit of epilepsy. And that therefore the exertions both of mind and body, both the voluntary ones, and those immediately excited by pleasurable sensation, were exertions to relieve pain.

The hunting scene appeared to be rather an act of memory than of imagination, and was therefore rather a voluntary exertion, though attended with the pleasurable eagerness, which was the consequence of those ideas recalled by recollection, and not the cause of them.

These ideas thus voluntarily recollected were succeeded by sensations of pleasure, though his senses were unaffected by the stimuli of visible or audible objects; or so weakly excited by them as not to produce sensation or attention. And the pleasure thus excited by volition produced other ideas and other motions in consequence of the sensorial power of sensation. Whence the mixed catenations of voluntary and sensitive ideas and muscular motions in reverie; which, like every other kind of vehement exertion, contribute to relieve pain, by expending a large quantity of sensorial power.

Those fits generally commence during sleep, from whence I suppose they have been thought to have some connection with sleep, and have thence been termed Somnambulism; but their commencement during sleep is owing to our increased excitability by internal sensations at that time, as explained in Sect. XVIII. 14. and 15., and not to any similitude between reverie and sleep.

3. I was once concerned for a very elegant and ingenious young lady, who had a reverie on alternate days, which continued nearly the whole day; and as in her days of disease she took up the same kind of ideas, which she had conversed about on the alternate day before, and could recollect nothing of them on her well-day; she appeared to her friends to possess two minds. This case also was of epileptic kind, and was cured, with some relapses, by opium administered before the commencement of the paroxysm.

4. Whence it appears, that the methods of relieving inflammatory pains, is by removing all stimulus, as by venesection, cool air, mucilaginous diet, aqueous potation, silence, darkness.

The methods of relieving pains from defect of stimulus is by supplying the peculiar stimulus required, as of food, or warmth.

And the general method of relieving pain is by exciting into action some great part of the system for the purpose of expending a part of the sensorial power. This is done either by exertion of the voluntary ideas and muscles, as in insanity and convulsion; or by exerting both voluntary and sensitive motions, as in reverie; or by exciting the irritative motions by wine or opium internally, and by the warm bath or blisters externally; or lastly, by exciting the sensitive ideas by good news, affecting stories, or agreeable passions.